Global to push GA events into
skip to main content

Title: Cellobiohydrolase variants and polynucleotides encoding the same

The present invention relates to variants of a parent cellobiohydrolase. The present invention also relates to polynucleotides encoding the cellobiohydrolase variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the cellobiohydrolase variants.
Inventors:
Issue Date:
OSTI Identifier:
1157571
Assignee:
Novozymes, Inc. (Davis, CA) GFO
Patent Number(s):
8,828,701
Application Number:
13/636,994
Contract Number:
FC36-08GO18080
Research Org:
Novozymes, Inc., Davis, CA (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Works referenced in this record:

Catalytic Plasticity of Fatty Acid Modification Enzymes Underlying Chemical Diversity of Plant Lipids
journal, November 1998

Semi-rational approaches to engineering enzyme activity: combining the benefits of directed evolution and rational design
journal, August 2005
  • Chica, Roberto A.; Doucet, Nicolas; Pelletier, Joelle N.
  • Current Opinion in Biotechnology, Vol. 16, Issue 4, p. 378-384
  • DOI: 10.1016/j.copbio.2005.06.004

Practical limits of function prediction
journal, January 2000

Genomic Islands in the Pathogenic Filamentous Fungus Aspergillus fumigatus
journal, April 2008
  • Fedorova, Natalie D.; Khaldi, Nora; Joardar, Vinita S.
  • PLoS Genetics, Vol. 4, Issue 4, Article No. e1000046
  • DOI: 10.1371/journal.pgen.1000046

Developments in Directed Evolution for Improving Enzyme Functions
journal, August 2007
  • Sen, S.; Venkata Dasu, V.; Mandal, B.
  • Applied Biochemistry and Biotechnology, Vol. 143, Issue 3, p. 212-223
  • DOI: 10.1007/s12010-007-8003-4

Prediction of protein function from protein sequence and structure
journal, January 1999
  • Whisstock, James C.; Lesk, Arthur M.
  • Quarterly Reviews of Biophysics, Vol. 36, Issue 3, p. 307-340
  • DOI: 10.1017/S0033583503003901

A Single Mutation Converts a Novel Phosphotyrosine Binding Domain into a Dual-specificity Phosphatase
journal, November 1995
  • Wishart, Matthew J.; Denu, John M.; Williams, John A.
  • Journal of Biological Chemistry, Vol. 270, Issue 45, p. 26782-26785
  • DOI: 10.1074/jbc.270.45.26782

SCHEMA Recombination of a Fungal Cellulase Uncovers a Single Mutation That Contributes Markedly to Stability
journal, July 2009
  • Heinzelman, Pete; Snow, Christopher D.; Smith, Matthew A.
  • Journal of Biological Chemistry, Vol. 284, Issue 39, p. 26229-26233
  • DOI: 10.1074/jbc.C109.034058

A family of thermostable fungal cellulases created by structure-guided recombination
journal, March 2009
  • Heinzelman, P.; Snow, C. D.; Wu, I.
  • Proceedings of the National Academy of Sciences, Vol. 106, Issue 14, p. 5610-5615
  • DOI: 10.1073/pnas.0901417106

Protein engineering in designing tailored enzymes and microorganisms for biofuels production
journal, August 2009