Targeted antimicrobials and related compositions, methods and systems

Jackson, Paul J.; Souza, Brian E.; Bourguet, Feliza A.; Coleman, Matthew A.

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Title: Targeted antimicrobials and related compositions, methods and systems

Abstract

Targeted antimicrobials are described and related, compositions, methods and systems.

Inventors:: Jackson, Paul J.; Souza, Brian E.; Bourguet, Feliza A.; Coleman, Matthew A.

Issue Date:: 2014-09-02

Research Org.:: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1154941

Patent Number(s):: 8821860

Application Number:: 12/852,358

Assignee:: Lawrence Livermore National Security, LLC (Livermore, CA)

Patent Classifications (CPCs):: A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

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A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A61K38/50 - acting on carbon-nitrogen bonds, other than peptide bonds
A61K45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P31/04 - Antibacterial agents

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C12P1/04 - by using bacteria

C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
C12Q1/18 - Testing for antimicrobial activity of a material

C - CHEMISTRY C12 - BIOCHEMISTRY C12Y - ENZYMES
C12Y305/01028 - N-Acetylmuramoyl-L-alanine amidase

G - PHYSICS G01 - MEASURING G01L - MEASURING FORCE, STRESS, TORQUE, WORK, MECHANICAL POWER, MECHANICAL EFFICIENCY, OR FLUID PRESSURE
G01L19/141 - {Monolithic housings, e.g. molded or one-piece housings}
G01L9/0052 - {of piezoresistive elements
G01L9/008 - {using piezoelectric devices
G01L9/08 - by making use of piezo-electric devices {, i.e. electric circuits therefor}

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N2333/32 - from Bacillus
G01N2333/914 - Hydrolases

H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01L - SEMICONDUCTOR DEVICES
H01L2224/73265 - Layer and wire connectors

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DOE Contract Number:: AC52-07NA27344

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: 59 BASIC BIOLOGICAL SCIENCES

Citation Formats


                    Jackson, Paul J., Souza, Brian E., Bourguet, Feliza A., and Coleman, Matthew A. Targeted antimicrobials and related compositions, methods and systems.  United States: N. p., 2014. 
        Web.

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                    Jackson, Paul J., Souza, Brian E., Bourguet, Feliza A., & Coleman, Matthew A. Targeted antimicrobials and related compositions, methods and systems.  United States.

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                    Jackson, Paul J., Souza, Brian E., Bourguet, Feliza A., and Coleman, Matthew A. Tue .  
        "Targeted antimicrobials and related compositions, methods and systems".  United States.  https://www.osti.gov/servlets/purl/1154941.

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@article{osti_1154941,

  title        = {Targeted antimicrobials and related compositions, methods and systems},

  author       = {Jackson, Paul J. and Souza, Brian E. and Bourguet, Feliza A. and Coleman, Matthew A.},

  abstractNote = {Targeted antimicrobials are described and related, compositions, methods and systems.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2014},

  month        = {9}

}

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Works referenced in this record:

Development of novel anti-microbial agents based on bacteriophage genomics
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Pelletier, Jerry; Gros, Philippe; DuBow, Michael
US Patent Document 6,783,930
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Purification and molecular characterization of glycylglycine endopeptidase produced by Staphylococcus capitis EPK1.
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The Complete Genome Sequence of Bacillus thuringiensis Al Hakam
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Virulent Bacteriophage for Efficient Biocontrol of Listeria monocytogenes in Ready-To-Eat Foods
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Applied and Environmental Microbiology, Vol. 75, Issue 1
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Fluorescent Amplified Fragment Length Polymorphism Analysis of Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis Isolates
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AmpD, essential for both ?-lactamase regulation and cell wall recycling, is a novel cytosolic N-acetylmuramyl-L-alanine amidase
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Similar Records

Title: Targeted antimicrobials and related compositions, methods and systems

Abstract

Citation Formats

Development of novel anti-microbial agents based on bacteriophage genomics patent, August 2004

Expression of recombinant mature lysostaphin patent, May 2005

Autolysins of Bacillus subtilis: multiple enzymes with multiple functions journal, February 2000

Cannibalism and fratricide: mechanisms and raisons d'être journal, March 2007

Three Bacillus cereus bacteriophage endolysins are unrelated but reveal high homology to cell wall hydrolases from different bacilli. journal, May 1997

Purification and molecular characterization of glycylglycine endopeptidase produced by Staphylococcus capitis EPK1. journal, February 1997

The Complete Genome Sequence of Bacillus thuringiensis Al Hakam journal, March 2007

Virulent Bacteriophage for Efficient Biocontrol of Listeria monocytogenes in Ready-To-Eat Foods journal, November 2008

Fluorescent Amplified Fragment Length Polymorphism Analysis of Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis Isolates journal, February 2004

AmpD, essential for both ?-lactamase regulation and cell wall recycling, is a novel cytosolic N-acetylmuramyl-L-alanine amidase journal, February 1995

Peptide Sequencing of 2-DE Gel-Isolated Proteins by Nanoelectrospray Tandem Mass Spectrometry book, January 1999

Polyamines Increase Antibiotic Susceptibility in Pseudomonas aeruginosa journal, April 2006

Bacteriophage endolysins — current state of research and applications journal, August 2005

C-terminal domains of Listeria monocytogenes bacteriophage murein hydrolases determine specific recognition and high-affinity binding to bacterial cell wall carbohydrates: Cell wall binding domains of Listeria phage lysins journal, April 2002

The Pneumococcal Cell Wall Degrading Enzymes: A Modular Design to Create New Lysins? journal, January 1997

Structure and Lytic Activity of a Bacillus anthracis Prophage Endolysin journal, August 2005

Yeast population dynamics during pilot-scale storage of grape marcs for the production of Grappa, a traditional Italian alcoholic beverage journal, February 2009

Application of In Vivo Induced Antigen Technology (IVIAT) to Bacillus anthracis journal, March 2008

Lytic activity of the recombinant staphylococcal bacteriophage ΦH5 endolysin active against Staphylococcus aureus in milk journal, December 2008

Preparative scale cell-free expression systems: New tools for the large scale preparation of integral membrane proteins for functional and structural studies journal, April 2007

Antimicrobial activity of a chimeric enzybiotic towards Staphylococcus aureus journal, January 2009

Nisin-Triggered Activity of Lys44, the Secreted Endolysin from Oenococcus oeni Phage fOg44 journal, November 2007

Development of novel anti-microbial agents based on bacteriophage genomics
patent, August 2004

Expression of recombinant mature lysostaphin
patent, May 2005

Autolysins of Bacillus subtilis: multiple enzymes with multiple functions
journal, February 2000

Cannibalism and fratricide: mechanisms and raisons d'être
journal, March 2007

Three Bacillus cereus bacteriophage endolysins are unrelated but reveal high homology to cell wall hydrolases from different bacilli.
journal, May 1997

Purification and molecular characterization of glycylglycine endopeptidase produced by Staphylococcus capitis EPK1.
journal, February 1997

The Complete Genome Sequence of Bacillus thuringiensis Al Hakam
journal, March 2007

Virulent Bacteriophage for Efficient Biocontrol of Listeria monocytogenes in Ready-To-Eat Foods
journal, November 2008

Fluorescent Amplified Fragment Length Polymorphism Analysis of Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis Isolates
journal, February 2004

AmpD, essential for both ?-lactamase regulation and cell wall recycling, is a novel cytosolic N-acetylmuramyl-L-alanine amidase
journal, February 1995

Peptide Sequencing of 2-DE Gel-Isolated Proteins by Nanoelectrospray Tandem Mass Spectrometry
book, January 1999

Polyamines Increase Antibiotic Susceptibility in Pseudomonas aeruginosa
journal, April 2006

Bacteriophage endolysins — current state of research and applications
journal, August 2005

C-terminal domains of Listeria monocytogenes bacteriophage murein hydrolases determine specific recognition and high-affinity binding to bacterial cell wall carbohydrates: Cell wall binding domains of Listeria phage lysins
journal, April 2002

The Pneumococcal Cell Wall Degrading Enzymes: A Modular Design to Create New Lysins?
journal, January 1997

Structure and Lytic Activity of a Bacillus anthracis Prophage Endolysin
journal, August 2005

Yeast population dynamics during pilot-scale storage of grape marcs for the production of Grappa, a traditional Italian alcoholic beverage
journal, February 2009

Application of In Vivo Induced Antigen Technology (IVIAT) to Bacillus anthracis
journal, March 2008

Lytic activity of the recombinant staphylococcal bacteriophage ΦH5 endolysin active against Staphylococcus aureus in milk
journal, December 2008

Preparative scale cell-free expression systems: New tools for the large scale preparation of integral membrane proteins for functional and structural studies
journal, April 2007

Antimicrobial activity of a chimeric enzybiotic towards Staphylococcus aureus
journal, January 2009

Nisin-Triggered Activity of Lys44, the Secreted Endolysin from Oenococcus oeni Phage fOg44
journal, November 2007