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Title: Nucleic acid compositions and the encoding proteins

The subject invention provides at least one nucleic acid sequence encoding an aldouronate-utilization regulon isolated from Paenibacillus sp. strain JDR-2, a bacterium which efficiently utilizes xylan and metabolizes aldouronates (methylglucuronoxylosaccharides). The subject invention also provides a means for providing a coordinately regulated process in which xylan depolymerization and product assimilation are coupled in Paenibacillus sp. strain JDR-2 to provide a favorable system for the conversion of lignocellulosic biomass to biobased products. Additionally, the nucleic acid sequences encoding the aldouronate-utilization regulon can be used to transform other bacteria to form organisms capable of producing a desired product (e.g., ethanol, 1-butanol, acetoin, 2,3-butanediol, 1,3-propanediol, succinate, lactate, acetate, malate or alanine) from lignocellulosic biomass.
Inventors:
; ; ; ;
Issue Date:
OSTI Identifier:
1154933
Assignee:
University of Florida Research Foundation, Inc. (Gainesville, FL) GFO
Patent Number(s):
8,822,179
Application Number:
13/350,858
Contract Number:
FG-02GO12026; FC36-99GO10476; FC36-00GO10594
Research Org:
Univ. of Florida, Gainesville, FL (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Other works cited in this record:

Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods
patent, December 2010

Bacteria engineered for fuel ethanol production: current status
journal, December 2003
  • Dien, B. S.; Cotta, M. A.; Jeffries, T. W.
  • Applied Microbiology and Biotechnology, Vol. 63, Issue 3, p. 258-266
  • DOI: 10.1007/s00253-003-1444-y

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