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Title: Unnatural reactive amino acid genetic code additions

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.
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OSTI Identifier:
The Scripps Research Institute (La Jolla, CA) OAK
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Research Org:
The Scripps Research Inst., La Jolla, CA (United States)
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Country of Publication:
United States

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