Platform for immobilization and observation of subcellular processes
Abstract
A method of immobilizing matter for imaging that includes providing an array of nanofibers and directing matter to the array of the nanofibers. The matter is immobilized when contacting at least three nanofibers of the array of nanofibers simultaneously. Adjacent nanofibers in the array of nanofibers may be separated by a pitch as great as 100 microns. The immobilized matter on the array of nanofibers may then be imaged. In some examples, the matter may be cell matter, such as protoplasts.
- Inventors:
- Issue Date:
- Research Org.:
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1151763
- Patent Number(s):
- 8,815,780
- Application Number:
- 13/369,849
- Assignee:
- UT-Battelle, LLC (Oak Ridge, TN)
- DOE Contract Number:
- AC05-000R22725
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
McKnight, Timothy E., Kalluri, Udaya C., and Melechko, Anatoli V. Platform for immobilization and observation of subcellular processes. United States: N. p., 2014.
Web.
McKnight, Timothy E., Kalluri, Udaya C., & Melechko, Anatoli V. Platform for immobilization and observation of subcellular processes. United States.
McKnight, Timothy E., Kalluri, Udaya C., and Melechko, Anatoli V. Tue .
"Platform for immobilization and observation of subcellular processes". United States. https://www.osti.gov/servlets/purl/1151763.
@article{osti_1151763,
title = {Platform for immobilization and observation of subcellular processes},
author = {McKnight, Timothy E. and Kalluri, Udaya C. and Melechko, Anatoli V.},
abstractNote = {A method of immobilizing matter for imaging that includes providing an array of nanofibers and directing matter to the array of the nanofibers. The matter is immobilized when contacting at least three nanofibers of the array of nanofibers simultaneously. Adjacent nanofibers in the array of nanofibers may be separated by a pitch as great as 100 microns. The immobilized matter on the array of nanofibers may then be imaged. In some examples, the matter may be cell matter, such as protoplasts.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {8}
}
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Nanoengineered membranes for controlled transport
patent, January 2010
- Doktycz, Mitchel; Simpson, Michael; McKnight, Timothy
- US Patent Document 7,641,863
Carbon tips with expanded bases
patent-application, August 2002
- Merkulov, Vladimir L.; Lowndes, Douglas H.; Guillorn, Michael A.
- US Patent Application 09/795660; 20020117951
Nanoengineered membranes for controlled transport
patent-application, September 2004
- Doktycz, Mitchel J.; Simpson, Michael L.; McKnight, Timothy E.
- US Patent Application 10/383309; 20040173506
Fluid delivery to cells and sensing properties of cells using nanotubes
patent-application, September 2004
- Shur, Michael; Dordick, Jonathan S.; Ajayan, Pulickel M.
- US Patent Application 10/393437; 20040186459
Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures
patent-application, October 2004
- McKnight, Timothy E.; Melechko, Anatoli V.; Griffin, Guy D.
- US Patent Application 10/408294; 20040197909
Individually addressable nanoelectrode array
patent-application, January 2005
- Kumar, Nalin
- US Patent Application 10/891224; 20050017173
Microscale and Nanoscale Structures for Manipulating Particles
patent-application, January 2014
- Chen, Grace; Fachin, Fabio; Toner, Mehmmet
- US Patent Application 13/812934; 20140030788
Culture and chemical-induced fusion of tobacco mesophyll protoplasts in a microfluidic device
journal, October 2010
- Wu, Heng; Liu, Wenming; Tu, Qin
- Microfluidics and Nanofluidics, Vol. 10, Issue 4
Tobacco protoplast culture in a polydimethylsiloxane-based microfluidic channel
journal, May 2006
- Ko, Jung-Moon; Ju, Jongil; Lee, SangHoon
- Protoplasma, Vol. 227, Issue 2-4