Laser ablation electrospray ionization (LAESI) for atmospheric pressure, in vivo, and imaging mass spectrometry
Abstract
The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation with electrospray ionization (ESI).
- Inventors:
- Issue Date:
- Research Org.:
- The George Washington University, Washington, DC (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1150637
- Patent Number(s):
- 8,809,774
- Application Number:
- 13/794,851
- Assignee:
- The George Washington University (Washington, DC)
- DOE Contract Number:
- FG02-01ER15129
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Vertes, Akos, and Nemes, Peter. Laser ablation electrospray ionization (LAESI) for atmospheric pressure, in vivo, and imaging mass spectrometry. United States: N. p., 2014.
Web.
Vertes, Akos, & Nemes, Peter. Laser ablation electrospray ionization (LAESI) for atmospheric pressure, in vivo, and imaging mass spectrometry. United States.
Vertes, Akos, and Nemes, Peter. Tue .
"Laser ablation electrospray ionization (LAESI) for atmospheric pressure, in vivo, and imaging mass spectrometry". United States. https://www.osti.gov/servlets/purl/1150637.
@article{osti_1150637,
title = {Laser ablation electrospray ionization (LAESI) for atmospheric pressure, in vivo, and imaging mass spectrometry},
author = {Vertes, Akos and Nemes, Peter},
abstractNote = {The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation with electrospray ionization (ESI).},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {8}
}
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Method and system for desorption electrospray ionization
patent, February 2008
- Takats, Zoltan; Gologan, Bogdan; Wiseman, Justin
- US Patent Document 7,335,897
Laser desorption--electrospray ion (ESI) source for mass spectrometers
patent, April 2009
- Kovtoun, Viatcheslav
- US Patent Document 7,525,105
Direct Protein Detection from Biological Media through Electrospray-Assisted Laser Desorption Ionization/Mass Spectrometry
journal, May 2006
- Huang, Min-Zong; Hsu, Hsiu-Jung; Lee, Jen-Yih
- Journal of Proteome Research, Vol. 5, Issue 5
Nanoscale Atmospheric Pressure Laser Ablation-Mass Spectrometry
journal, April 2001
- Stöckle, Raoul; Setz, Patrick; Deckert, Volker
- Analytical Chemistry, Vol. 73, Issue 7
Laser Desorption-Atmospheric Pressure Chemical Ionization Mass Spectrometry for the Analysis of Peptides from Aqueous Solutions
journal, November 2002
- Coon, Joshua J.; Harrison, W. W.
- Analytical Chemistry, Vol. 74, Issue 21
New dimension in nano-imaging: breaking through the diffraction limit with scanning near-field optical microscopy
journal, November 2004
- Rasmussen, Akiko; Deckert, Volker
- Analytical and Bioanalytical Chemistry, Vol. 381, Issue 1
Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization
journal, October 2004
- Takats, Z.
- Science, Vol. 306, Issue 5695, p. 471-473
Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions
journal, April 2005
- Cody, Robert B.; Laramée, James A.; Durst, H. Dupont
- Analytical Chemistry, Vol. 77, Issue 8, p. 2297-2302
Laser Ablation Electrospray Ionization for Atmospheric Pressure, in Vivo, and Imaging Mass Spectrometry
journal, November 2007
- Nemes, Peter; Vertes, Akos
- Analytical Chemistry, Vol. 79, Issue 21
Recent Advances in Optical Tweezers
journal, June 2008
- Moffitt, Jeffrey R.; Chemla, Yann R.; Smith, Steven B.
- Annual Review of Biochemistry, Vol. 77, Issue 1
Simultaneous Imaging of Small Metabolites and Lipids in Rat Brain Tissues at Atmospheric Pressure by Laser Ablation Electrospray Ionization Mass Spectrometry
journal, February 2010
- Nemes, Peter; Woods, Amina S.; Vertes, Akos
- Analytical Chemistry, Vol. 82, Issue 3
In Situ Metabolic Profiling of Single Cells by Laser Ablation Electrospray Ionization Mass Spectrometry
journal, October 2009
- Shrestha, Bindesh; Vertes, Akos
- Analytical Chemistry, Vol. 81, Issue 20
Intact and top-down characterization of biomolecules and direct analysis using infrared matrix-assisted laser desorption electrospray ionization coupled to FT-ICR mass spectrometry
journal, April 2009
- Sampson, Jason S.; Murray, Kermit K.; Muddiman, David C.
- Journal of the American Society for Mass Spectrometry, Vol. 20, Issue 4, p. 667-673
Infrared laser-assisted desorption electrospray ionization mass spectrometry
journal, January 2008
- Rezenom, Yohannes H.; Dong, Jianan; Murray, Kermit K.
- The Analyst, Vol. 133, Issue 2
Ablation and analysis of small cell populations and single cells by consecutive laser pulses
journal, June 2010
- Shrestha, Bindesh; Nemes, Peter; Vertes, Akos
- Applied Physics A, Vol. 101, Issue 1
Free-electron-laser-based biophysical and biomedical instrumentation
journal, July 2003
- Edwards, G. S.; Austin, R. H.; Carroll, F. E.
- Review of Scientific Instruments, Vol. 74, Issue 7
FT-IR imaging of native and tissue-engineered bone and cartilage
journal, May 2007
- Boskey, A.; Pleshkocamacho, N.
- Biomaterials, Vol. 28, Issue 15
Matrix-assisted laser desorption and ionization in the OH and CO absorption bands of aliphatic and aromatic matrices: dependence on laser wavelength and temporal beam profile
journal, December 1997
- Cramer, Rainer; Haglund, Richard F.; Hillenkamp, Franz
- International Journal of Mass Spectrometry and Ion Processes, Vol. 169-170, p. 51-67
Three-Dimensional Imaging of Metabolites in Tissues under Ambient Conditions by Laser Ablation Electrospray Ionization Mass Spectrometry
journal, August 2009
- Nemes, Peter; Barton, Alexis A.; Vertes, Akos
- Analytical Chemistry, Vol. 81, Issue 16
Ambient Molecular Imaging and Depth Profiling of Live Tissue by Infrared Laser Ablation Electrospray Ionization Mass Spectrometry
journal, June 2008
- Nemes, Peter; Barton, Alexis A.; Li, Yue
- Analytical Chemistry, Vol. 80, Issue 12
Infrared Laser Ablation Atmospheric Pressure Photoionization Mass Spectrometry
journal, January 2012
- Vaikkinen, Anu; Shrestha, Bindesh; Kauppila, Tiina J.
- Analytical Chemistry, Vol. 84, Issue 3
Elevated subcortical choline metabolites in cognitively and clinically asymptomatic HIV patients
journal, March 1999
- Meyerhoff, D. J.; Bloomer, C.; Cardenas, V.
- Neurology, Vol. 52, Issue 5
High Precision Isotope Ratio Monitoring Techniques in Mass Spectrometry
journal, March 1996
- Brand, Willi A.
- Journal of Mass Spectrometry, Vol. 31, Issue 3, p. 225-235
Laser spray: electric field-assisted matrix-assisted laser desorption/ionization
journal, April 2004
- Hiraoka, Kenzo
- Journal of Mass Spectrometry, Vol. 39, Issue 4