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Title: Method and system for real-time analysis of biosensor data

A method of biosensor-based detection of toxins includes the steps of providing a fluid to be analyzed having a plurality of photosynthetic organisms therein, wherein chemical, biological or radiological agents alter a nominal photosynthetic activity of the photosynthetic organisms. At a first time a measured photosynthetic activity curve is obtained from the photosynthetic organisms. The measured curve is automatically compared to a reference photosynthetic activity curve to determine differences therebetween. The presence of the chemical, biological or radiological agents, or precursors thereof, are then identified if present in the fluid using the differences.
Inventors:
;
Issue Date:
OSTI Identifier:
1150220
Assignee:
UT-Battelle, LLC (Oak Ridge, TN) ORNL
Patent Number(s):
8,812,239
Application Number:
11/302,844
Contract Number:
AC05-00OR22725
Research Org:
ORNL (Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States))
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Other works cited in this record:

A simple in vitro fluorescence method for biomass measurements in algal growth inhibition tests
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Calorimetric biosensors with integrated microfluidic channels
journal, July 2004
  • Zhang, Yuyan; Tadigadapa, Srinivas
  • Biosensors and Bioelectronics, Vol. 19, Issue 12, p. 1733-1743
  • DOI: 10.1016/j.bios.2004.01.009

Stand-off tissue-based biosensors for the detection of chemical warfare agents using photosynthetic fluorescence induction
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  • Sanders, Charlene A.; Rodriguez, Miguel; Greenbaum, Elias
  • Biosensors and Bioelectronics, Vol. 16, Issue 7-8, p. 439-446
  • DOI: 10.1016/S0956-5663(01)00158-0

Magnetic resonance as a technique to magnetic biosensors characterization in Neocapritermes opacus termites
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Biosensors for rapid monitoring of primary-source drinking water using naturally occurring photosynthesis
journal, October 2002
  • Rodriguez, Miguel; Sanders, Charlene A.; Greenbaum, Elias
  • Biosensors and Bioelectronics, Vol. 17, Issue 10, p. 843-849
  • DOI: 10.1016/S0956-5663(02)00059-3

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