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Title: Radio-methyl vorozole and methods for making and using the same

Abstract

Radiotracer vorozole compounds for in vivo and in vitro assaying, studying and imaging cytochrome P450 aromatase enzymes in humans, animals, and tissues and methods for making and using the same are provided. [N-radio-methyl] vorozole substantially separated from an N-3 radio-methyl isomer of vorozole is provided. Separation is accomplished through use of chromatography resins providing multiple mechanisms of selectivity.

Inventors:
; ;
Issue Date:
Research Org.:
Brookhaven National Lab. (BNL), Upton, NY (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1150092
Patent Number(s):
8802053
Application Number:
13/847,136
Assignee:
Brookhaven Science Associates, LLC (Upton, NY)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07D - HETEROCYCLIC COMPOUNDS
DOE Contract Number:  
AC02-98CH10886
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Kim, Sung Won, Biegon, Anat, and Fowler, Joanna S. Radio-methyl vorozole and methods for making and using the same. United States: N. p., 2014. Web.
Kim, Sung Won, Biegon, Anat, & Fowler, Joanna S. Radio-methyl vorozole and methods for making and using the same. United States.
Kim, Sung Won, Biegon, Anat, and Fowler, Joanna S. Tue . "Radio-methyl vorozole and methods for making and using the same". United States. https://www.osti.gov/servlets/purl/1150092.
@article{osti_1150092,
title = {Radio-methyl vorozole and methods for making and using the same},
author = {Kim, Sung Won and Biegon, Anat and Fowler, Joanna S.},
abstractNote = {Radiotracer vorozole compounds for in vivo and in vitro assaying, studying and imaging cytochrome P450 aromatase enzymes in humans, animals, and tissues and methods for making and using the same are provided. [N-radio-methyl] vorozole substantially separated from an N-3 radio-methyl isomer of vorozole is provided. Separation is accomplished through use of chromatography resins providing multiple mechanisms of selectivity.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {8}
}

Patent:

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