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Title: Genes related to xylose fermentation and methods of using same for enhanced biofuel production

The present invention provides isolated gene sequences involved in xylose fermentation and related recombinant yeast which are useful in methods of enhanced biofuel production, particularly ethanol production. Methods of bioengineering recombinant yeast useful for biofuel production are also provided.
Inventors:
;
Issue Date:
OSTI Identifier:
1150005
Assignee:
Wisconsin Alumni Research Foundation (Madison, WI) CHO
Patent Number(s):
8,795,996
Application Number:
13/441,381
Contract Number:
FC02-07ER64494
Research Org:
Wisconsin Alumni Research Foundation, Madison, WI (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Other works cited in this record:

Structural and functional properties of aldose xylose reductase from the d-xylose-metabolizing yeast Candida tenuis
journal, January 2001

Comparative genomics of xylose-fermenting fungi for enhanced biofuel production
journal, July 2011
  • Wohlbach, D. J.; Kuo, A.; Sato, T. K.
  • Proceedings of the National Academy of Sciences, Vol. 108, Issue 32, p. 13212-13217
  • DOI: 10.1073/pnas.1103039108

The crystal structure of the GCY1 protein from S. cerevisiae suggests a divergent aldo-keto reductase catalytic mechanism
journal, January 2001

Engineering yeasts for xylose metabolism
journal, June 2006

Reduced Oxidative Pentose Phosphate Pathway Flux in Recombinant Xylose-Utilizing Saccharomyces cerevisiae Strains Improves the Ethanol Yield from Xylose
journal, April 2002
  • Jeppsson, Marie; Johansson, Bjorn; Hahn-Hagerdal, Barbel
  • Applied and Environmental Microbiology, Vol. 68, Issue 4, p. 1604-1609
  • DOI: 10.1128/AEM.68.4.1604-1609.2002

Elimination of Glycerol Production in Anaerobic Cultures of a Saccharomyces cerevisiae Strain Engineered To Use Acetic Acid as an Electron Acceptor
journal, November 2009
  • Medina, Victor; Almering, Marinka; van Maris, Antonius
  • Applied and Environmental Microbiology, Vol. 76, Issue 1, p. 190-195
  • DOI: 10.1128/AEM.01772-09

Morphological and ecological similarities: wood-boring beetles associated with novel xylose-fermenting yeasts, Spathaspora passalidarum gen. sp. nov. and Candida jeffriesii sp. nov.
journal, October 2006
  • Nguyen, Nhu H.; Suh, Sung-Oui; Marshall, Christopher J.
  • Mycological Research, Vol. 110, Issue 10, p. 1232-1241
  • DOI: 10.1016/j.mycres.2006.07.002

Purification and properties of the NAD+-xylitol-dehydrogenase from the yeast Pichia stipitis
journal, January 1989
  • Rizzi, Manfred; Harwart, Katharina; Erlemann, Petra
  • Journal of Fermentation and Bioengineering, Vol. 67, Issue 1, p. 20-24
  • DOI: 10.1016/0922-338X(89)90080-9

Construction of xylose-assimilating Saccharomyces cerevisiae
journal, January 1993
  • Tantirungkij, Manee; Nakashima, Noriyuki; Seki, Tatsuji
  • Journal of Fermentation and Bioengineering, Vol. 75, Issue 2, p. 83-88
  • DOI: 10.1016/0922-338X(93)90214-S

Yeast metabolic engineering for hemicellulosic ethanol production
journal, June 2009

Glycerol production by microbial fermentation
journal, June 2001

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