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Title: Ultrasonic analyte concentration and application in flow cytometry

Abstract

The present invention includes an apparatus and corresponding method for concentrating analytes within a fluid flowing through a tube using acoustic radiation pressure. The apparatus includes a function generator that outputs a radio frequency electrical signal to a transducer that transforms the radio frequency electric signal to an acoustic signal and couples the acoustic signal to the tube. The acoustic signal is converted within the tube to acoustic pressure that concentrates the analytes within the fluid.

Inventors:
; ; ; ; ; ;
Issue Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1149911
Patent Number(s):
8783109
Application Number:
11/982,042
Assignee:
Los Alamos National Security, LLC (Los Alamos, NM)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC52-06NA25396
Resource Type:
Patent
Resource Relation:
Patent File Date: 2007 Oct 31
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Kaduchak, Gregory, Goddard, Greg, Salzman, Gary, Sinha, Dipen, Martin, John C., Kwiatkowski, Christopher, and Graves, Steven. Ultrasonic analyte concentration and application in flow cytometry. United States: N. p., 2014. Web.
Kaduchak, Gregory, Goddard, Greg, Salzman, Gary, Sinha, Dipen, Martin, John C., Kwiatkowski, Christopher, & Graves, Steven. Ultrasonic analyte concentration and application in flow cytometry. United States.
Kaduchak, Gregory, Goddard, Greg, Salzman, Gary, Sinha, Dipen, Martin, John C., Kwiatkowski, Christopher, and Graves, Steven. Tue . "Ultrasonic analyte concentration and application in flow cytometry". United States. https://www.osti.gov/servlets/purl/1149911.
@article{osti_1149911,
title = {Ultrasonic analyte concentration and application in flow cytometry},
author = {Kaduchak, Gregory and Goddard, Greg and Salzman, Gary and Sinha, Dipen and Martin, John C. and Kwiatkowski, Christopher and Graves, Steven},
abstractNote = {The present invention includes an apparatus and corresponding method for concentrating analytes within a fluid flowing through a tube using acoustic radiation pressure. The apparatus includes a function generator that outputs a radio frequency electrical signal to a transducer that transforms the radio frequency electric signal to an acoustic signal and couples the acoustic signal to the tube. The acoustic signal is converted within the tube to acoustic pressure that concentrates the analytes within the fluid.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {7}
}

Patent:

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