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Title: Water-soluble carbon nanotube compositions for drug delivery and medicinal applications

Abstract

Compositions comprising a plurality of functionalized carbon nanotubes and at least one type of payload molecule are provided herein. The compositions are soluble in water and PBS in some embodiments. In certain embodiments, the payload molecules are insoluble in water. Methods are described for making the compositions and administering the compositions. An extended release formulation for paclitaxel utilizing functionalized carbon nanotubes is also described.

Inventors:
; ; ; ; ; ; ; ; ; ; ; ;
Issue Date:
Research Org.:
Rice Univ., Houston, TX (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1149690
Patent Number(s):
8,784,866
Application Number:
12/245,438
Assignee:
William Marsh Rice University (Houston, TX); Board of Regents, The University of Texas System (Austin, TX)
DOE Contract Number:  
FC36-05GO15073
Resource Type:
Patent
Resource Relation:
Patent File Date: 2008 Oct 03
Country of Publication:
United States
Language:
English
Subject:
77 NANOSCIENCE AND NANOTECHNOLOGY

Citation Formats

Tour, James M., Lucente-Schultz, Rebecca, Leonard, Ashley, Kosynkin, Dmitry V., Price, Brandi Katherine, Hudson, Jared L., Conyers, Jr., Jodie L., Moore, Valerie C., Casscells, S. Ward, Myers, Jeffrey N., Milas, Zvonimir L., Mason, Kathy A., and Milas, Luka. Water-soluble carbon nanotube compositions for drug delivery and medicinal applications. United States: N. p., 2014. Web.
Tour, James M., Lucente-Schultz, Rebecca, Leonard, Ashley, Kosynkin, Dmitry V., Price, Brandi Katherine, Hudson, Jared L., Conyers, Jr., Jodie L., Moore, Valerie C., Casscells, S. Ward, Myers, Jeffrey N., Milas, Zvonimir L., Mason, Kathy A., & Milas, Luka. Water-soluble carbon nanotube compositions for drug delivery and medicinal applications. United States.
Tour, James M., Lucente-Schultz, Rebecca, Leonard, Ashley, Kosynkin, Dmitry V., Price, Brandi Katherine, Hudson, Jared L., Conyers, Jr., Jodie L., Moore, Valerie C., Casscells, S. Ward, Myers, Jeffrey N., Milas, Zvonimir L., Mason, Kathy A., and Milas, Luka. Tue . "Water-soluble carbon nanotube compositions for drug delivery and medicinal applications". United States. https://www.osti.gov/servlets/purl/1149690.
@article{osti_1149690,
title = {Water-soluble carbon nanotube compositions for drug delivery and medicinal applications},
author = {Tour, James M. and Lucente-Schultz, Rebecca and Leonard, Ashley and Kosynkin, Dmitry V. and Price, Brandi Katherine and Hudson, Jared L. and Conyers, Jr., Jodie L. and Moore, Valerie C. and Casscells, S. Ward and Myers, Jeffrey N. and Milas, Zvonimir L. and Mason, Kathy A. and Milas, Luka},
abstractNote = {Compositions comprising a plurality of functionalized carbon nanotubes and at least one type of payload molecule are provided herein. The compositions are soluble in water and PBS in some embodiments. In certain embodiments, the payload molecules are insoluble in water. Methods are described for making the compositions and administering the compositions. An extended release formulation for paclitaxel utilizing functionalized carbon nanotubes is also described.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {7}
}

Patent:

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