Methods for making nucleotide probes for sequencing and synthesis

Church, George M; Zhang, Kun; Chou, Joseph

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Title: Methods for making nucleotide probes for sequencing and synthesis

Abstract

Compositions and methods for making a plurality of probes for analyzing a plurality of nucleic acid samples are provided. Compositions and methods for analyzing a plurality of nucleic acid samples to obtain sequence information in each nucleic acid sample are also provided.

Inventors:: Church, George M; Zhang, Kun; Chou, Joseph

Issue Date:: 2014-07-08

Research Org.:: Harvard College, Cambridge, MA (USA).

Sponsoring Org.:: USDOE

OSTI Identifier:: 1140127

Patent Number(s):: 8771950

Application Number:: 12/187,460

Assignee:: President and Fellows of Harvard College (Cambridge, MA)

Patent Classifications (CPCs):: C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS

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C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
C12Q1/6813 - Hybridisation assays
C12Q1/6837 - using probe arrays or probe chips
C12Q2535/113 - Cycle sequencing
C12Q2537/143 - Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
C12Q2565/543 - characterised by the use of two or more capture oligonucleotide primers in concert, e.g. bridge amplification

Show less

DOE Contract Number:: FG02-02ER63445

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: 60 APPLIED LIFE SCIENCES

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                    Church, George M, Zhang, Kun, and Chou, Joseph. Methods for making nucleotide probes for sequencing and synthesis.  United States: N. p., 2014. 
        Web.

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                    Church, George M, Zhang, Kun, & Chou, Joseph. Methods for making nucleotide probes for sequencing and synthesis.  United States.

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                    Church, George M, Zhang, Kun, and Chou, Joseph. Tue .  
        "Methods for making nucleotide probes for sequencing and synthesis".  United States.  https://www.osti.gov/servlets/purl/1140127.

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@article{osti_1140127,

  title        = {Methods for making nucleotide probes for sequencing and synthesis},

  author       = {Church, George M and Zhang, Kun and Chou, Joseph},

  abstractNote = {Compositions and methods for making a plurality of probes for analyzing a plurality of nucleic acid samples are provided. Compositions and methods for analyzing a plurality of nucleic acid samples to obtain sequence information in each nucleic acid sample are also provided.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2014},

  month        = {7}

}

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