Apparatus and method of dissociating ions in a multipole ion guide
Abstract
A method of dissociating ions in a multipole ion guide is disclosed. A stream of charged ions is supplied to the ion guide. A main RF field is applied to the ion guide to confine the ions through the ion guide. An excitation RF field is applied to one pair of rods of the ion guide. The ions undergo dissociation when the applied excitation RF field is resonant with a secular frequency of the ions. The multipole ion guide is, but not limited to, a quadrupole, a hexapole, and an octopole.
- Inventors:
- Issue Date:
- Research Org.:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1137094
- Patent Number(s):
- 8772711
- Application Number:
- 14/011,529
- Assignee:
- Battelle Memorial Institute (Richland, WA)
- Patent Classifications (CPCs):
-
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- DOE Contract Number:
- AC05-76RL01830
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS
Citation Formats
Webb, Ian K., Tang, Keqi, Smith, Richard D., Ibrahim, Yehia M., and Anderson, Gordon A. Apparatus and method of dissociating ions in a multipole ion guide. United States: N. p., 2014.
Web.
Webb, Ian K., Tang, Keqi, Smith, Richard D., Ibrahim, Yehia M., & Anderson, Gordon A. Apparatus and method of dissociating ions in a multipole ion guide. United States.
Webb, Ian K., Tang, Keqi, Smith, Richard D., Ibrahim, Yehia M., and Anderson, Gordon A. Tue .
"Apparatus and method of dissociating ions in a multipole ion guide". United States. https://www.osti.gov/servlets/purl/1137094.
@article{osti_1137094,
title = {Apparatus and method of dissociating ions in a multipole ion guide},
author = {Webb, Ian K. and Tang, Keqi and Smith, Richard D. and Ibrahim, Yehia M. and Anderson, Gordon A.},
abstractNote = {A method of dissociating ions in a multipole ion guide is disclosed. A stream of charged ions is supplied to the ion guide. A main RF field is applied to the ion guide to confine the ions through the ion guide. An excitation RF field is applied to one pair of rods of the ion guide. The ions undergo dissociation when the applied excitation RF field is resonant with a secular frequency of the ions. The multipole ion guide is, but not limited to, a quadrupole, a hexapole, and an octopole.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {7}
}
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Works referenced in this record:
Method of and apparatus for selective collision-induced dissociation of ions in a quadrupole ion guide
patent, January 2003
- Loboda, Alexandre; Krouttchinskikh, Andrei; Spicer, Victor L.
- US Patent Document 6,512,226
Mass spectrometry with multipole ion guides
patent, June 2004
- Whitehouse, Craig M.; Andrien, Jr., Bruce A.; Gulcicek, Erol
- US Patent Document 6,753,523
High-Q pulsed fragmentation in ion traps
patent, September 2005
- Schwartz, Jae C.
- US Patent Document 6,949,743
Mass spectrometry with segmented RF multiple ion guides in various pressure regions
patent, April 2006
- Whitehouse, Craig M.; Welkie, David G.; Javahery, Gholamreza
- US Patent Document 7,034,292
Mass spectrometry with segmented RF multiple ion guides in various pressure regions
patent, December 2010
- Whitehouse, Craig M.; Welkie, David G.; Javahery, Gholamreza
- US Patent Document 7,858,926
High performance micro-fabricated electrostatic quadrupole lens
patent-application, August 2008
- Syms, Richard
- US Patent Application 12/012000; 20080185518
The focusing of an ion beam from a quadrupole mass filter using an electrostatic octopole lens
journal, October 1978
- Birkinshaw, K.; Hirst, D. M.; Jarrold, M. F.
- Journal of Physics E: Scientific Instruments, Vol. 11, Issue 10
High amplitude short time excitation: A method to form and detect low mass product ions in a quadrupole ion trap mass spectrometer
journal, January 2006
- Cunningham, Connell; Glish, Gary L.; Burinsky, David J.
- Journal of the American Society for Mass Spectrometry, Vol. 17, Issue 1, p. 81-84
MS3 using the collision cell of a tandem mass spectrometer system
journal, January 2002
- Cousins, Lisa M.; Thomson, Bruce A.
- Rapid Communications in Mass Spectrometry, Vol. 16, Issue 11
A new technique for decomposition of selected ions in molecule ion reactor coupled with ortho-time-of-flight mass spectrometry
journal, October 1997
- Dodonov, A.; Kozlovsky, V.; Loboda, A.
- Rapid Communications in Mass Spectrometry, Vol. 11, Issue 15, p. 1649-1656
Proteomics on an Orbitrap Benchtop Mass Spectrometer Using All-ion Fragmentation
journal, July 2010
- Geiger, Tamar; Cox, Juergen; Mann, Matthias
- Molecular & Cellular Proteomics, Vol. 9, Issue 10
Targeted Data Extraction of the MS/MS Spectra Generated by Data-independent Acquisition: A New Concept for Consistent and Accurate Proteome Analysis
journal, January 2012
- Gillet, Ludovic C.; Navarro, Pedro; Tate, Stephen
- Molecular & Cellular Proteomics, Vol. 11, Issue 6
Establishing low-energy sequential decomposition pathways of leucine enkephalin and its N- and C-terminus fragments using multiple-resonance CID in quadrupolar ion guide
journal, December 2004
- Rakov, V. Sergey; Borisov, Oleg V.; Whitehouse, Craig M.
- Journal of the American Society for Mass Spectrometry, Vol. 15, Issue 12, p. 1794-1809