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Title: Pantothenic acid biosynthesis in zymomonas

Abstract

Zymomonas is unable to synthesize pantothenic acid and requires this essential vitamin in growth medium. Zymomonas strains transformed with an operon for expression of 2-dehydropantoate reductase and aspartate 1-decarboxylase were able to grow in medium lacking pantothenic acid. These strains may be used for ethanol production without pantothenic acid supplementation in seed culture and fermentation media.

Inventors:
; ;
Issue Date:
Research Org.:
E I du Pont de Nemours and Company, Wilmington, DE (USA)
Sponsoring Org.:
USDOE
OSTI Identifier:
1136700
Patent Number(s):
8765426
Application Number:
13/433,343
Assignee:
E I du Pont de Nemours and Company (Wilmington, DE)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
DOE Contract Number:  
FC36-07GO17056
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Tao, Luan, Tomb, Jean-Francois, and Viitanen, Paul V. Pantothenic acid biosynthesis in zymomonas. United States: N. p., 2014. Web.
Tao, Luan, Tomb, Jean-Francois, & Viitanen, Paul V. Pantothenic acid biosynthesis in zymomonas. United States.
Tao, Luan, Tomb, Jean-Francois, and Viitanen, Paul V. Tue . "Pantothenic acid biosynthesis in zymomonas". United States. https://www.osti.gov/servlets/purl/1136700.
@article{osti_1136700,
title = {Pantothenic acid biosynthesis in zymomonas},
author = {Tao, Luan and Tomb, Jean-Francois and Viitanen, Paul V.},
abstractNote = {Zymomonas is unable to synthesize pantothenic acid and requires this essential vitamin in growth medium. Zymomonas strains transformed with an operon for expression of 2-dehydropantoate reductase and aspartate 1-decarboxylase were able to grow in medium lacking pantothenic acid. These strains may be used for ethanol production without pantothenic acid supplementation in seed culture and fermentation media.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jul 01 00:00:00 EDT 2014},
month = {Tue Jul 01 00:00:00 EDT 2014}
}

Works referenced in this record:

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patent, May 1996


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patent, January 1998


Mutant E. coli kiz strains for production of pantothenic acid
patent, January 2001


Zymomonas pentose-sugar fermenting strains and uses thereof
patent, May 2007


Ethanol production in fermentation of mixed sugars containing xylose
patent, December 2009


Ethanol production using xylitol synthesis mutant of xylose-utilizing zymomonas
patent, June 2010


Xylitol synthesis mutant of xylose-utilizing zymomonas for ethanol production
patent, June 2010


Treatment of biomass to obtain fermentable sugars
patent, April 2011


Zymomonas with improved xylose utilization
patent, August 2011


Methods and microorganisms for production of panto-compounds
patent-application, April 2005


Alanine 2,3,aminomutase
patent-application, October 2005


Alanine 2, 3 Aminomutases
patent-application, January 2009


Pentose metabolism in Zymomonas mobilis wild-type and recombinant strains
journal, December 1992


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The KEGG databases at GenomeNet
journal, January 2002


An improved synthetic medium for continuous cultivation of Zymomonas mobilis
journal, April 1984


The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4
journal, December 2004


Metabolic Engineering of a Pentose Metabolism Pathway in Ethanologenic Zymomonas mobilis
journal, January 1995


    Works referencing / citing this record:

    Pantothenic acid biosynthesis in zymomonas
    patent, July 2014