Pantothenic acid biosynthesis in zymomonas

Tao, Luan; Tomb, Jean-Francois; Viitanen, Paul V.

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Title: Pantothenic acid biosynthesis in zymomonas

Abstract

Zymomonas is unable to synthesize pantothenic acid and requires this essential vitamin in growth medium. Zymomonas strains transformed with an operon for expression of 2-dehydropantoate reductase and aspartate 1-decarboxylase were able to grow in medium lacking pantothenic acid. These strains may be used for ethanol production without pantothenic acid supplementation in seed culture and fermentation media.

Inventors:: Tao, Luan; Tomb, Jean-Francois; Viitanen, Paul V.

Issue Date:: 2014-07-01

Research Org.:: E I du Pont de Nemours and Company, Wilmington, DE (USA)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1136700

Patent Number(s):: 8765426

Application Number:: 13/433,343

Assignee:: E I du Pont de Nemours and Company (Wilmington, DE)

Patent Classifications (CPCs):: C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {

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C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C12N15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
C12N9/0006 - {acting on CH-OH groups as donors
C12N9/88 - Lyases

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C12P13/02 - Amides, e.g. chloramphenicol {or polyamides
C12P7/06 - Ethanol, i.e. non-beverage
C12P7/065 - {with microorganisms other than yeasts}

C - CHEMISTRY C12 - BIOCHEMISTRY C12Y - ENZYMES
C12Y101/01169 - 2-Dehydropantoate 2-reductase
C12Y401/01011 - Aspartate 1-decarboxylase

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE Y02E - REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
Y02E50/10 - Biofuels

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DOE Contract Number:: FC36-07GO17056

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: 59 BASIC BIOLOGICAL SCIENCES

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                    Tao, Luan, Tomb, Jean-Francois, and Viitanen, Paul V. Pantothenic acid biosynthesis in zymomonas.  United States: N. p., 2014. 
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                    Tao, Luan, Tomb, Jean-Francois, & Viitanen, Paul V. Pantothenic acid biosynthesis in zymomonas.  United States.

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                    Tao, Luan, Tomb, Jean-Francois, and Viitanen, Paul V. Tue .  
        "Pantothenic acid biosynthesis in zymomonas".  United States.  https://www.osti.gov/servlets/purl/1136700.

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@article{osti_1136700,

  title        = {Pantothenic acid biosynthesis in zymomonas},

  author       = {Tao, Luan and Tomb, Jean-Francois and Viitanen, Paul V.},

  abstractNote = {Zymomonas is unable to synthesize pantothenic acid and requires this essential vitamin in growth medium. Zymomonas strains transformed with an operon for expression of 2-dehydropantoate reductase and aspartate 1-decarboxylase were able to grow in medium lacking pantothenic acid. These strains may be used for ethanol production without pantothenic acid supplementation in seed culture and fermentation media.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2014},

  month        = {7}

}

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Works referencing / citing this record: