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Title: Pantothenic acid biosynthesis in zymomonas

Abstract

Zymomonas is unable to synthesize pantothenic acid and requires this essential vitamin in growth medium. Zymomonas strains transformed with an operon for expression of 2-dehydropantoate reductase and aspartate 1-decarboxylase were able to grow in medium lacking pantothenic acid. These strains may be used for ethanol production without pantothenic acid supplementation in seed culture and fermentation media.

Inventors:
; ;
Issue Date:
Research Org.:
E I du Pont de Nemours and Company, Wilmington, DE (USA)
Sponsoring Org.:
USDOE
OSTI Identifier:
1136700
Patent Number(s):
8765426
Application Number:
13/433,343
Assignee:
E I du Pont de Nemours and Company (Wilmington, DE)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C - CHEMISTRY C12 - BIOCHEMISTRY C12Y - ENZYMES
DOE Contract Number:  
FC36-07GO17056
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Tao, Luan, Tomb, Jean-Francois, and Viitanen, Paul V. Pantothenic acid biosynthesis in zymomonas. United States: N. p., 2014. Web.
Tao, Luan, Tomb, Jean-Francois, & Viitanen, Paul V. Pantothenic acid biosynthesis in zymomonas. United States.
Tao, Luan, Tomb, Jean-Francois, and Viitanen, Paul V. Tue . "Pantothenic acid biosynthesis in zymomonas". United States. https://www.osti.gov/servlets/purl/1136700.
@article{osti_1136700,
title = {Pantothenic acid biosynthesis in zymomonas},
author = {Tao, Luan and Tomb, Jean-Francois and Viitanen, Paul V.},
abstractNote = {Zymomonas is unable to synthesize pantothenic acid and requires this essential vitamin in growth medium. Zymomonas strains transformed with an operon for expression of 2-dehydropantoate reductase and aspartate 1-decarboxylase were able to grow in medium lacking pantothenic acid. These strains may be used for ethanol production without pantothenic acid supplementation in seed culture and fermentation media.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {7}
}

Works referenced in this record:

Pentose metabolism in Zymomonas mobilis wild-type and recombinant strains
journal, December 1992


KEGG: Kyoto Encyclopedia of Genes and Genomes
journal, January 2000


The KEGG databases at GenomeNet
journal, January 2002


An improved synthetic medium for continuous cultivation of Zymomonas mobilis
journal, April 1984


The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4
journal, December 2004


Metabolic Engineering of a Pentose Metabolism Pathway in Ethanologenic Zymomonas mobilis
journal, January 1995