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Title: Sheathless interface for coupling capillary electrophoresis with mass spectrometry

Abstract

A sheathless interface for coupling capillary electrophoresis (CE) with mass spectrometry is disclosed. The sheathless interface includes a separation capillary for performing CE separation and an emitter capillary for electrospray ionization. A portion of the emitter capillary is porous or, alternatively, is coated to form an electrically conductive surface. A section of the emitter capillary is disposed within the separation capillary, forming a joint. A metal tube, containing a conductive liquid, encloses the joint.

Inventors:
; ;
Issue Date:
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1134337
Patent Number(s):
8,754,370
Application Number:
13/788,854
Assignee:
Battelle Memorial Institute (Richland, WA)
DOE Contract Number:  
AC05-76RLO1830
Resource Type:
Patent
Resource Relation:
Patent File Date: 2013 Mar 07
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; 59 BASIC BIOLOGICAL SCIENCES; 47 OTHER INSTRUMENTATION

Citation Formats

Wang, Chenchen, Tang, Keqi, and Smith, Richard D. Sheathless interface for coupling capillary electrophoresis with mass spectrometry. United States: N. p., 2014. Web.
Wang, Chenchen, Tang, Keqi, & Smith, Richard D. Sheathless interface for coupling capillary electrophoresis with mass spectrometry. United States.
Wang, Chenchen, Tang, Keqi, and Smith, Richard D. Tue . "Sheathless interface for coupling capillary electrophoresis with mass spectrometry". United States. https://www.osti.gov/servlets/purl/1134337.
@article{osti_1134337,
title = {Sheathless interface for coupling capillary electrophoresis with mass spectrometry},
author = {Wang, Chenchen and Tang, Keqi and Smith, Richard D.},
abstractNote = {A sheathless interface for coupling capillary electrophoresis (CE) with mass spectrometry is disclosed. The sheathless interface includes a separation capillary for performing CE separation and an emitter capillary for electrospray ionization. A portion of the emitter capillary is porous or, alternatively, is coated to form an electrically conductive surface. A section of the emitter capillary is disposed within the separation capillary, forming a joint. A metal tube, containing a conductive liquid, encloses the joint.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {6}
}

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Works referenced in this record:

Modified liquid junction interface for nonaqueous capillary electrophoresis-mass spectrometry
journal, September 2000


Capillary Electrophoresis to Mass Spectrometry Interface Using a Porous Junction
journal, May 2003

  • Whitt, Jacob T.; Moini, Mehdi
  • Analytical Chemistry, Vol. 75, Issue 9
  • DOI: 10.1021/ac026380j

Capillary electrophoresis–electrospray ionization-mass spectrometry interfaces: Fundamental concepts and technical developments
journal, December 2012


Isotachophoresis as an on-line concentration pretreatment technique in capillary electrophoresis
journal, January 1991


Ultrasensitive Sample Quantitation via Selected Reaction Monitoring Using CITP/CZE–ESI-Triple Quadrupole MS
journal, November 2012

  • Wang, Chenchen; Lee, Cheng S.; Smith, Richard D.
  • Analytical Chemistry, Vol. 84, Issue 23
  • DOI: 10.1021/ac302616m

Characterization of the Microdialysis Junction Interface for Capillary Electrophoresis/Microelectrospray Ionization Mass Spectrometry
journal, June 1997

  • Severs, Joanne C.; Smith, Richard D.
  • Analytical Chemistry, Vol. 69, Issue 11
  • DOI: 10.1021/ac9611226