Modified cyanobacteria

Vermaas, Willem F J.

Title: Modified cyanobacteria

Abstract

Disclosed is a modified photoautotrophic bacterium comprising genes of interest that are modified in terms of their expression and/or coding region sequence, wherein modification of the genes of interest increases production of a desired product in the bacterium relative to the amount of the desired product production in a photoautotrophic bacterium that is not modified with respect to the genes of interest.

Inventors:: Vermaas, Willem F J.

Issue Date:: 2014-06-17

Research Org.:: Arizona State University, Scottsdale, AZ (United States). Arizona Board of Regents

Sponsoring Org.:: USDOE

OSTI Identifier:: 1134228

Patent Number(s):: 8753840

Application Number:: 12/446,441

Assignee:: Arizona Board of Regents on behalf of Arizona State University (Scottsdale, AZ)

Patent Classifications (CPCs):: C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE Y02E - REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION

Show more

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C12P23/00 - Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
C12P7/6409 - {Fatty acids}
C12P7/6463 - {obtained from glyceride producing microorganisms, e.g. single cell oil}

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE Y02E - REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
Y02E50/10 - Biofuels

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C12P7/649 - {Biodiesel, i.e. Fatty acid alkyl esters}
C12P7/625 - {Polyesters of hydroxy-carboxylic acids}

Show less

DOE Contract Number:: FG03-01ER15251

Resource Type:: Patent

Resource Relation:: Patent File Date: 2007 Oct 19

Country of Publication:: United States

Language:: English

Subject:: 59 BASIC BIOLOGICAL SCIENCES

Citation Formats


                    Vermaas, Willem F J. Modified cyanobacteria.  United States: N. p., 2014. 
        Web.

Copy to clipboard


                    Vermaas, Willem F J. Modified cyanobacteria.  United States.

Copy to clipboard


                    Vermaas, Willem F J. Tue .  
        "Modified cyanobacteria".  United States.  https://www.osti.gov/servlets/purl/1134228.

Copy to clipboard


                    
@article{osti_1134228,

  title        = {Modified cyanobacteria},

  author       = {Vermaas, Willem F J.},

  abstractNote = {Disclosed is a modified photoautotrophic bacterium comprising genes of interest that are modified in terms of their expression and/or coding region sequence, wherein modification of the genes of interest increases production of a desired product in the bacterium relative to the amount of the desired product production in a photoautotrophic bacterium that is not modified with respect to the genes of interest.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2014},

  month        = {6}

}

Copy to clipboard

Patent:

Save / Share:

Export Metadata

Save to My Library

Works referenced in this record:

Protein tolerance to random amino acid change
journal, June 2004

Guo, H. H.; Choe, J.; Loeb, L. A.
Proceedings of the National Academy of Sciences, Vol. 101, Issue 25, p. 9205-9210
https://doi.org/10.1073/pnas.0403255101

Transforming growth factor alpha: mutation of aspartic acid 47 and leucine 48 results in different biological activities.
journal, March 1988

Lazar, E.; Watanabe, S.; Dalton, S.
Molecular and Cellular Biology, Vol. 8, Issue 3, p. 1247-1252
https://doi.org/10.1128/MCB.8.3.1247

Functional Analysis of Conserved Histidines in ADP-Glucose Pyrophosphorylase from Escherichia coli
journal, March 1998

Hill, Margaret A.; Preiss, Jack
Biochemical and Biophysical Research Communications, Vol. 244, Issue 2, p. 573-577
https://doi.org/10.1006/bbrc.1998.8301

Disentangling the perturbational effects of amino acid substitutions in the DNA-binding domain of p53
journal, February 1999

Wacey, A. I.; Cooper, D. N.; Liney, D.
Human Genetics, Vol. 104, Issue 1, p. 15-22
https://doi.org/10.1007/s004390050904

Sequence Analysis of the Genome of the Unicellular Cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence Features in the 1 Mb Region from Map Positions 64% to 92% of the Genome (Supplement)
journal, January 1995

Kaneko, T.
DNA Research, Vol. 2, Issue 4
https://doi.org/10.1093/dnares/2.4.191

Polyhydroxyalkanoates: an overview
journal, April 2003

Reddy, C. S. K.; Ghai, R.
Bioresource Technology, Vol. 87, Issue 2, p. 137-146
https://doi.org/10.1016/S0960-8524(02)00212-2

An SmtB-like repressor from Synechocystis PCC 6803 regulates a zinc exporter
journal, September 1998

Thelwell, C.; Robinson, N. J.; Turner-Cavet, J. S.
Proceedings of the National Academy of Sciences, Vol. 95, Issue 18
https://doi.org/10.1073/pnas.95.18.10728

Overproduction of Acetyl-CoA Carboxylase Activity Increases the Rate of Fatty Acid Biosynthesis in Escherichia coli
journal, July 2000

Davis, Mark S.; Solbiati, José; Cronan, John E.
Journal of Biological Chemistry, Vol. 275, Issue 37, p. 28593-28598
https://doi.org/10.1074/jbc.M004756200

A host-vector system for gene cloning in the cyanobacterium Synechocystis PCC 6803
journal, July 1986

Chauvat, F.; De Vries, L.; Van der Ende, A.
Molecular and General Genetics MGG, Vol. 204, Issue 1
https://doi.org/10.1007/BF00330208

Vipp1 deletion mutant of Synechocystis: A connection between bacterial phage shock and thylakoid biogenesis?
journal, March 2001

Westphal, S.; Heins, L.; Soll, J.
Proceedings of the National Academy of Sciences, Vol. 98, Issue 7, p. 4243-4248
https://doi.org/10.1073/pnas.061501198

VIPP1, a nuclear gene of Arabidopsis thaliana essential for thylakoid membrane formation
journal, March 2001

Kroll, D.; Meierhoff, K.; Bechtold, N.
Proceedings of the National Academy of Sciences, Vol. 98, Issue 7, p. 4238-4242
https://doi.org/10.1073/pnas.061500998

Effects of co-expression of two higher plants genes ALD and TPI in Anabaena sp. PCC7120 on photosynthetic CO₂ fixation
journal, March 2005

Kang, Rui-Juan; Shi, Ding-Ji; Cong, Wei
Enzyme and Microbial Technology, Vol. 36, Issue 4, p. 600-604
https://doi.org/10.1016/j.enzmictec.2004.12.017

Exogenous expression of the wheat chloroplastic fructose-1,6-bisphosphatase gene enhances photosynthesis in the transgenic cyanobacterium, Anabaena PCC7120
journal, May 2005

Ma, Weimin; Shi, Dingji; Wang, Quanxi
Journal of Applied Phycology, Vol. 17, Issue 3
https://doi.org/10.1007/s10811-005-4850-y

Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942
journal, November 1999

Omata, T.; Price, G. D.; Badger, M. R.
Proceedings of the National Academy of Sciences, Vol. 96, Issue 23
https://doi.org/10.1073/pnas.96.23.13571

Distribution of the mevalonate and glyceraldehyde phosphate/pyruvate pathways for isoprenoid biosynthesis in unicellular algae and the cyanobacterium Synechocystis PCC 6714
journal, July 1998

Disch, Andrea; Schwender, Jörg; MÜLler, Christian
Biochemical Journal, Vol. 333, Issue 2
https://doi.org/10.1042/bj3330381

Engineering a platform for photosynthetic isoprene production in cyanobacteria, using Synechocystis as the model organism
journal, January 2010

Lindberg, Pia; Park, Sungsoon; Melis, Anastasios
Metabolic Engineering, Vol. 12, Issue 1, p. 70-79
https://doi.org/10.1016/j.ymben.2009.10.001

Emissions of hydrocarbons from marine phytoplankton—Some results from controlled laboratory experiments
journal, July 1996

McKay, W. A.; Turner, M. F.; Jones, B. M. R.
Atmospheric Environment, Vol. 30, Issue 14, p. 2583-2593
https://doi.org/10.1016/1352-2310(95)00433-5

First isolation of an isoprene synthase gene from poplar and successful expression of the gene in Escherichia coli
journal, July 2001

Miller, Barbara; Oschinski, Christa; Zimmer, Wolfgang
Planta, Vol. 213, Issue 3
https://doi.org/10.1007/s004250100557

Inactivation of sll1556 in Synechocystis Strain PCC 6803 Impairs Isoprenoid Biosynthesis from Pentose Phosphate Cycle Substrates In Vitro
journal, July 2004

Poliquin, K.; Ershov, Y. V.; Cunningham, F. X.
Journal of Bacteriology, Vol. 186, Issue 14
https://doi.org/10.1128/JB.186.14.4685-4693.2004

Gene expression and characterization of isoprene synthase from Populus alba
journal, April 2005

Sasaki, Kanako; Ohara, Kazuaki; Yazaki, Kazufumi
FEBS Letters, Vol. 579, Issue 11, p. 2514-2518
https://doi.org/10.1016/j.febslet.2005.03.066

Role of NtcB in Activation of Nitrate Assimilation Genes in the Cyanobacterium Synechocystis sp. Strain PCC 6803
journal, October 2001

Aichi, M.; Takatani, N.; Omata, T.
Journal of Bacteriology, Vol. 183, Issue 20
https://doi.org/10.1128/JB.183.20.5840-5847.2001

Cyanobacterial Cell Inclusions
journal, October 1984

Allen, M. M.
Annual Review of Microbiology, Vol. 38, Issue 1
https://doi.org/10.1146/annurev.mi.38.100184.000245

Restoration of the wild-type locus in an RuBP carboxylase/oxygenase mutant of Synecbocystis PCC 6803 via targeted gene recombination
journal, November 1992

Amichay, Doron; Sheffer, Meir; Gurevitz, Michael
MGG Molecular & General Genetics, Vol. 235, Issue 2-3
https://doi.org/10.1007/BF00279367

Production of biodiesel from macroalgae by supercritical CO2 extraction and thermochemical liquefaction
journal, November 2005

Aresta, Michele; Dibenedetto, Angela; Carone, Maria
Environmental Chemistry Letters, Vol. 3, Issue 3
https://doi.org/10.1007/s10311-005-0020-3

Photosynthetic accumulation of poly-(hydroxybutyrate) by cyanobacteria—the metabolism and potential for CO₂ recycling
journal, June 1999

Asada, Yasuo; Miyake, Masato; Miyake, Jun
International Journal of Biological Macromolecules, Vol. 25, Issue 1-3, p. 37-42
https://doi.org/10.1016/S0141-8130(99)00013-6

Separation of Small Circular DNA Molecules from the Blue–green Alga Anacystis nidulans
journal, August 1973

Asato, Yukio; Ginoza, Herbert S.
Nature New Biology, Vol. 244, Issue 135
https://doi.org/10.1038/newbio244132a0

Blunt-end and single-strand ligations by Escherichia coli ligase: influence on an in vitro amplication scheme
journal, April 1990

Barringer, Kevin J.; Orgel, Leslie; Wahl, Geoff
Gene, Vol. 89, Issue 1, p. 117-122
https://doi.org/10.1016/0378-1119(90)90213-B

Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
journal, January 1981

Beaucage, S. L.; Caruthers, M. H.
Tetrahedron Letters, Vol. 22, Issue 20, p. 1859-1862
https://doi.org/10.1016/S0040-4039(01)90461-7

Gene Transfer to the Desiccation-Tolerant Cyanobacterium Chroococcidiopsis
journal, April 2001

Billi, D.; Friedmann, E. I.; Helm, R. F.
Journal of Bacteriology, Vol. 183, Issue 7
https://doi.org/10.1128/JB.183.7.2298-2305.2001

Fast formation of high-purity methyl esters from vegetable oils
journal, December 1998

Boocock, David G. B.; Konar, Samir K.; Mao, V.
Journal of the American Oil Chemists' Society, Vol. 75, Issue 12
https://doi.org/10.1007/s11746-998-0307-1

Normalisation of sister chromatid exchange frequencies in Bloom's syndrome by euploid cell hybridisation
journal, June 1979

Bryant, Eileen M.; Hoehn, Holger; Martin, George M.
Nature, Vol. 279, Issue 5716
https://doi.org/10.1038/279795a0

In vitro scanning saturation mutagenesis of an antibody binding pocket
journal, January 1997

Burks, E. A.; Chen, G.; Georgiou, G.
Proceedings of the National Academy of Sciences, Vol. 94, Issue 2
https://doi.org/10.1073/pnas.94.2.412

Randomization of genes by PCR mutagenesis.
journal, August 1992

Cadwell, R. C.; Joyce, G. F.
Genome Research, Vol. 2, Issue 1, p. 28-33
https://doi.org/10.1101/gr.2.1.28

A plasmid vector for isolation of strong promoters in Escherichia coli
journal, August 1999

Carbonelli, Daniela L.; Corley, Esteban; Seigelchifer, Mauricio
FEMS Microbiology Letters, Vol. 177, Issue 1, p. 75-82
https://doi.org/10.1111/j.1574-6968.1999.tb13716.x

The occurrence of poly-β-hydroxybutyrate in the blue-green alga, Chlorogloea fritschii
journal, June 1966

Carr, N. G.
Biochimica et Biophysica Acta (BBA) - Biophysics including Photosynthesis, Vol. 120, Issue 2, p. 308-310
https://doi.org/10.1016/0926-6585(66)90353-0

RNA splicing specificity determined by the coordinated action of RNA recognition motifs in SR proteins
journal, April 1997

Chandler, S. D.; Mayeda, A.; Yeakley, J. M.
Proceedings of the National Academy of Sciences, Vol. 94, Issue 8
https://doi.org/10.1073/pnas.94.8.3596

High-efficiency transformation of mammalian cells by plasmid DNA.
journal, August 1987

Chen, C.; Okayama, H.
Molecular and Cellular Biology, Vol. 7, Issue 8
https://doi.org/10.1128/MCB.7.8.2745

Recovery in aqueous two-phase systems of lutein produced by the green microalga Chlorella protothecoides
journal, July 2004

Cisneros, M.; Benavides, J.; Brenes, C.
Journal of Chromatography B, Vol. 807, Issue 1
https://doi.org/10.1016/j.jchromb.2004.01.009

Succinate Dehydrogenase and Other Respiratory Pathways in Thylakoid Membranes of Synechocystis sp. Strain PCC 6803: Capacity Comparisons and Physiological Function
journal, July 2001

Cooley, J. W.; Vermaas, W. F. J.
Journal of Bacteriology, Vol. 183, Issue 14
https://doi.org/10.1128/JB.183.14.4251-4258.2001

Succinate:Quinol Oxidoreductases in the Cyanobacterium Synechocystis sp. Strain PCC 6803: Presence and Function in Metabolism and Electron Transport
journal, February 2000

Cooley, J. W.; Howitt, C. A.; Vermaas, W. F. J.
Journal of Bacteriology, Vol. 182, Issue 3
https://doi.org/10.1128/JB.182.3.714-722.2000

Insertional mutagenesis of the Drosophila genome with single P elements
journal, March 1988

Cooley, L.; Kelley, R.; Spradling, A.
Science, Vol. 239, Issue 4844
https://doi.org/10.1126/science.2830671

High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis
journal, June 1989

Cunningham, B.; Wells, J.
Science, Vol. 244, Issue 4908
https://doi.org/10.1126/science.2471267

Phospholipid:diacylglycerol acyltransferase: An enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants
journal, May 2000

Dahlqvist, A.; Stahl, U.; Lenman, M.
Proceedings of the National Academy of Sciences, Vol. 97, Issue 12, p. 6487-6492
https://doi.org/10.1073/pnas.120067297

Factors affecting poly-β-hydroxybutyrate accumulation in cyanobacteria and in purple non-sulfur bacteria
journal, December 1992

De Philippis, R.
FEMS Microbiology Letters, Vol. 103, Issue 2-4
https://doi.org/10.1016/0378-1097(92)90309-C

Glycogen and poly- -hydroxybutyrate synthesis in Spirulina maxima
journal, August 1992

De Philippis, R.; Sili, C.; Vincenzini, M.
Journal of General Microbiology, Vol. 138, Issue 8
https://doi.org/10.1099/00221287-138-8-1623

Ethanol production from cellulose by coupled saccharification/fermentation usingSaccharomyces cerevisiae and cellulase complex fromSclerotiun rolfsii UV-8 mutant
journal, September 1992

Deshpande, Mukund V.
Applied Biochemistry and Biotechnology, Vol. 36, Issue 3, p. 227-234
https://doi.org/10.1007/BF02921781

Phycobilisomes of the Thermophilic Blue-Green alga Synechococcus Lividus
journal, September 1971

Edwards, M. R.
The Journal of Cell Biology, Vol. 50, Issue 3
https://doi.org/10.1083/jcb.50.3.896

Transfection of mammalian cells with plasmid DNA by scrape loading and sonication loading.
journal, December 1987

Fechheimer, M.; Boylan, J. F.; Parker, S.
Proceedings of the National Academy of Sciences, Vol. 84, Issue 23
https://doi.org/10.1073/pnas.84.23.8463

Entrapment of a bacterial plasmid in phospholipid vesicles: potential for gene transfer.
journal, July 1979

Fraley, R. T.; Fornari, C. S.; Kaplan, S.
Proceedings of the National Academy of Sciences, Vol. 76, Issue 7
https://doi.org/10.1073/pnas.76.7.3348

Gene transfer method for transient gene expression, stable transformation, and cotransformation of suspension cell cultures.
journal, May 1985

Gopal, T. V.
Molecular and Cellular Biology, Vol. 5, Issue 5
https://doi.org/10.1128/MCB.5.5.1188

A new technique for the assay of infectivity of human adenovirus 5 DNA
journal, April 1973

Graham, F. L.; van der Eb, A. J.
Virology, Vol. 52, Issue 2, p. 456-467
https://doi.org/10.1016/0042-6822(73)90341-3

Transformation in the cyanobacterium Synechocystis sp. 6803
journal, April 1982

Grigorieva, G.; Shestakov, S.
FEMS Microbiology Letters, Vol. 13, Issue 4, p. 367-370
https://doi.org/10.1111/j.1574-6968.1982.tb08289.x

Isothermal, in vitro amplification of nucleic acids by a multienzyme reaction modeled after retroviral replication.
journal, March 1990

Guatelli, J. C.; Whitfield, K. M.; Kwoh, D. Y.
Proceedings of the National Academy of Sciences, Vol. 87, Issue 5, p. 1874-1878
https://doi.org/10.1073/pnas.87.5.1874

Radiation Response Characteristics of Human Cells in Vitro
journal, June 1988

Hall, E. J.; Marchese, M.; Hei, T. K.
Radiation Research, Vol. 114, Issue 3
https://doi.org/10.2307/3577115

Translation of mRNA injected into Xenopus oocytes is specifically inhibited by antisense RNA
journal, September 1985

Harland, R.
The Journal of Cell Biology, Vol. 101, Issue 3
https://doi.org/10.1083/jcb.101.3.1094

Expression of a higher plant light-harvesting chlorophyll a/b-binding protein in Synechocystis sp. PCC 6803
journal, July 1999

He, Qingfang; Schlich, Thomas; Paulsen, Harald
European Journal of Biochemistry, Vol. 263, Issue 2
https://doi.org/10.1046/j.1432-1327.1999.00526.x

Synechocystis sp. PCC6803 possesses a two-component polyhydroxyalkanoic acid synthase similar to that of anoxygenic purple sulfur bacteria
journal, August 1998

Hein, Silke; Tran, H.; Steinbüchel, A.
Archives of Microbiology, Vol. 170, Issue 3
https://doi.org/10.1007/s002030050629

Saturation Mutagenesis of the WSXWS Motif of the Erythropoietin Receptor
journal, March 1996

Watowich, S. S.
Journal of Biological Chemistry, Vol. 271, Issue 9
https://doi.org/10.1074/jbc.271.9.4699

Quinol and Cytochrome Oxidases in the Cyanobacterium Synechocystis sp. PCC 6803 ^†
journal, December 1998

Howitt, Crispin A.; Vermaas, Wim F. J.
Biochemistry, Vol. 37, Issue 51
https://doi.org/10.1021/bi981486n

A strain of Synechocystis sp. PCC 6803 without photosynthetic oxygen evolution and respiratory oxygen consumption: implications for the study of cyclic photosynthetic electron transport
journal, November 2001

Howitt, Crispin A.; Cooley, Jason W.; Wiskich, Joseph T.
Planta, Vol. 214, Issue 1
https://doi.org/10.1007/s004250100578

Up-promoter mutations in the lpp gene of Escherichia coli
journal, January 1985

Inouye, Sumiko; Inouye, Masayori
Nucleic Acids Research, Vol. 13, Issue 9
https://doi.org/10.1093/nar/13.9.3101

Species variation in the specificity of ribulose biphosphate carboxylase/oxygenase
journal, June 1981

Jordan, Douglas B.; Ogren, William L.
Nature, Vol. 291, Issue 5815
https://doi.org/10.1038/291513a0

Increased expression of DNA cointroduced with nuclear protein in adult rat liver
journal, January 1989

Kaneda, Y.; Iwai, K.; Uchida, T.
Science, Vol. 243, Issue 4889
https://doi.org/10.1126/science.2911748

High-Performance Liquid Chromatography Analysis of Oxidized and Reduced Pyridine Dinucleotides in Specific Brain Regions
journal, July 1995

Klaidman, L. K.; Leung, A. C.; Adams, J. D.
Analytical Biochemistry, Vol. 228, Issue 2
https://doi.org/10.1006/abio.1995.1356

Transcription-based amplification system and detection of amplified human immunodeficiency virus type 1 with a bead-based sandwich hybridization format.
journal, February 1989

Kwoh, D. Y.; Davis, G. R.; Whitfield, K. M.
Proceedings of the National Academy of Sciences, Vol. 86, Issue 4, p. 1173-1177
https://doi.org/10.1073/pnas.86.4.1173

Increased Production of Zeaxanthin and Other Pigments by Application of Genetic Engineering Techniques to Synechocystis sp. Strain PCC 6803
journal, January 2000

Lagarde, D.; Beuf, L.; Vermaas, W.
Applied and Environmental Microbiology, Vol. 66, Issue 1
https://doi.org/10.1128/AEM.66.1.64-72.2000

Effect of growth conditions on endo- and exopolymer biosynthesis in Anabaena cylindrica 10 C
journal, June 1996

Lama, Licia; Nicolaus, Barbara; Calandrelli, Valeria
Phytochemistry, Vol. 42, Issue 3, p. 655-659
https://doi.org/10.1016/0031-9422(95)00985-X

X-ray-Induced Changes in Gene lt Expression in Normal and r, Oncogene-Transformed Rat Cell Lines
journal, November 1988

Lambert, M.; Borek, C.
JNCI Journal of the National Cancer Institute, Vol. 80, Issue 18
https://doi.org/10.1093/jnci/80.18.1492

A ligase-mediated gene detection technique
journal, August 1988

Landegren, U.; Kaiser, R.; Sanders, J.
Science, Vol. 241, Issue 4869
https://doi.org/10.1126/science.3413476

Internal Ribosomal Entry Site-Containing Retroviral Vectors with Green Fluorescent Protein and Drug Resistance Markers
journal, May 1998

Levenson, Victor V.; Transue, Erin D. E.; Roninson, Igor B.
Human Gene Therapy, Vol. 9, Issue 8
https://doi.org/10.1089/hum.1998.9.8-1233

Purification and Characterization of the Poly(Hydroxyalkanoic Acid) Synthase from Chromatium vinosum and Localization of the Enzyme at the Surface of Poly(Hydroxyalkanoic Acid) Granules
journal, November 1994

Liebergesell, Matthias; Sonomoto, Kenji; Madkour, Mohamed
European Journal of Biochemistry, Vol. 226, Issue 1
https://doi.org/10.1111/j.1432-1033.1994.00t71.x

Control of polyhydroxyalkanoate synthesis in Azotobacter vinelandii strain UWD
journal, April 1994

Manchak, J.; Page, W. J.
Microbiology, Vol. 140, Issue 4
https://doi.org/10.1099/00221287-140-4-953

By-passing immunization: Human antibodies from V-gene libraries displayed on phage
journal, December 1991

Marks, James D.; Hoogenboom, Hennie R.; Bonnert, Timothy P.
Journal of Molecular Biology, Vol. 222, Issue 3, p. 581-597
https://doi.org/10.1016/0022-2836(91)90498-U

Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids.
journal, March 1975

McCann, J.; Spingarn, N. E.; Kobori, J.
Proceedings of the National Academy of Sciences, Vol. 72, Issue 3
https://doi.org/10.1073/pnas.72.3.979

Inorganic Carbon Limitation and Light Control the Expression of Transcripts Related to the CO ₂ -Concentrating Mechanism in the Cyanobacterium Synechocystis sp. Strain PCC6803
journal, April 2003

McGinn, Patrick J.; Price, G. Dean; Maleszka, Ryszard
Plant Physiology, Vol. 132, Issue 1
https://doi.org/10.1104/pp.019349

Regulation of glutamine synthetase activity in the unicellular cyanobacterium Synechocystis sp. strain PCC 6803 by the nitrogen source: effect of ammonium.
journal, July 1991

Mérida, A.; Candau, P.; Florencio, F. J.
Journal of Bacteriology, Vol. 173, Issue 13
https://doi.org/10.1128/jb.173.13.4095-4100.1991

Polyhydroxybutyrate Production from Carbon Dioxide by Cyanobacteria
journal, January 2000

Miyake, Masato; Takase, Kazuya; Narato, Midori
Applied Biochemistry and Biotechnology, Vol. 84-86, Issue 1-9
https://doi.org/10.1385/ABAB:84-86:1-9:991

A thermophilic cyanobacterium, Synechococcus sp. MA19, capable of accumulating poly-β-hydroxybutyrate
journal, January 1996

Miyake, Masato; Erata, Mayumi; Asada, Yasuo
Journal of Fermentation and Bioengineering, Vol. 82, Issue 5, p. 512-514
https://doi.org/10.1016/S0922-338X(97)86995-4

Myxoxanthophyll Is Required for Normal Cell Wall Structure and Thylakoid Organization in the Cyanobacterium Synechocystis sp. Strain PCC 6803
journal, September 2005

Mohamed, H. E.; van de Meene, A. M. L.; Roberson, R. W.
Journal of Bacteriology, Vol. 187, Issue 20
https://doi.org/10.1128/JB.187.20.6883-6892.2005

Recombinant gene expression in vivo within endothelial cells of the arterial wall
journal, June 1989

Nabel, E.; Plautz, G.; Boyce, F.
Science, Vol. 244, Issue 4910
https://doi.org/10.1126/science.2499928

Complete Genome Structure of the Thermophilic Cyanobacterium Thermosynechococcus elongatus BP-1
journal, January 2002

Nakamura, Y.
DNA Research, Vol. 9, Issue 4, p. 123-130
https://doi.org/10.1093/dnares/9.4.123

Microbial Production of Hydrogen: An Overview
journal, January 1998

Nandi, R.; Sengupta, S.
Critical Reviews in Microbiology, Vol. 24, Issue 1
https://doi.org/10.1080/10408419891294181

Liposome-mediated DNA transfer in eukaryotic cells: Dependence of the transfer efficiency upon the type of liposomes used and the host cell cycle stage
journal, October 1982

Nicolau, Claude; Sene, Claude
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Vol. 721, Issue 2, p. 185-190
https://doi.org/10.1016/0167-4889(82)90067-2

Supercritical carbon dioxide extraction of astaxanthin and other carotenoids from the microalga Haematococcus pluvialis
journal, March 2006

Nobre, Beatriz; Marcelo, Filipa; Passos, Renata
European Food Research and Technology, Vol. 223, Issue 6
https://doi.org/10.1007/s00217-006-0270-8

A Lecithin Cholesterol Acyltransferase-like Gene Mediates Diacylglycerol Esterification in Yeast
journal, March 2000

Oelkers, Peter; Tinkelenberg, Arthur; Erdeniz, Naz
Journal of Biological Chemistry, Vol. 275, Issue 21
https://doi.org/10.1074/jbc.C000144200

A gene homologous to the subunit-2 gene of NADH dehydrogenase is essential to inorganic carbon transport of Synechocystis PCC6803.
journal, May 1991

Ogawa, T.
Proceedings of the National Academy of Sciences, Vol. 88, Issue 10
https://doi.org/10.1073/pnas.88.10.4275

A myb gene required for leaf trichome differentiation in Arabidopsis is expressed in stipules
journal, November 1991

Oppenheimer, David G.; Herman, Patricia L.; Sivakumaran, Shan
Cell, Vol. 67, Issue 3, p. 483-493
https://doi.org/10.1016/0092-8674(91)90523-2

Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation.
journal, November 1984

Potter, H.; Weir, L.; Leder, P.
Proceedings of the National Academy of Sciences, Vol. 81, Issue 22
https://doi.org/10.1073/pnas.81.22.7161

The Photobiological Production of Hydrogen: Potential Efficiency and Effectiveness as a Renewable Fuel
journal, January 2005

Prince, Roger C.; Kheshgi, Haroon S.
Critical Reviews in Microbiology, Vol. 31, Issue 1
https://doi.org/10.1080/10408410590912961

Low molecular weight complexed poly(3-hydroxybutyrate): a dynamic and versatile molecule in vivo
journal, December 1995

Reusch, Rosetta N.
Canadian Journal of Microbiology, Vol. 41, Issue 13
https://doi.org/10.1139/m95-167

Generic Assignments, Strain Histories and Properties of Pure Cultures of Cyanobacteria
journal, March 1979

Stanier, Roger Y.; Deruelles, Josette; Rippka, Rosmarie
Microbiology, Vol. 111, Issue 1, p. 1-61
https://doi.org/10.1099/00221287-111-1-1

DNA-mediated gene transfer into adult rat hepatocytes in primary culture.
journal, February 1990

Rippe, R. A.; Brenner, D. A.; Leffert, H. L.
Molecular and Cellular Biology, Vol. 10, Issue 2
https://doi.org/10.1128/MCB.10.2.689

Electron Microscope Studies on Blue-Green Algae
journal, January 1961

Ris, H.
The Journal of Cell Biology, Vol. 9, Issue 1
https://doi.org/10.1083/jcb.9.1.63

Practical application of aqueous two-phase partition to process development for the recovery of biological products
journal, July 2004

Ritopalomares, M.
Journal of Chromatography B, Vol. 807, Issue 1
https://doi.org/10.1016/j.jchromb.2004.01.008

The blue-green alga agmenellum quadruplicatum contains covalently closed DNA circles
journal, December 1976

Roberts, Thomas M.; Koths, Kirston E.
Cell, Vol. 9, Issue 4, p. 551-557
https://doi.org/10.1016/0092-8674(76)90037-4

A cyanobacterial narB gene encodes a ferredoxin-dependent nitrate reductase
journal, February 1996

Rubio, Luis M.; Herrero, Antonia; Flores, Enrique
Plant Molecular Biology, Vol. 30, Issue 4
https://doi.org/10.1007/BF00019017

Transposon tagging and molecular analysis of the maize regulatory locus opaque-2
journal, November 1987

Schmidt, R.; Burr, F.; Burr, B.
Science, Vol. 238, Issue 4829
https://doi.org/10.1126/science.2823388

Production and biotransformation of 6-pentyl-α-pyrone by Trichoderma harzianum in two-phase culture systems
journal, January 2002

Serrano-Carreón, K. Baldera, L.
Applied Microbiology and Biotechnology, Vol. 58, Issue 2
https://doi.org/10.1007/s00253-001-0874-7

Effect of modifying metabolic network on poly-3-hydroxybutyrate biosynthesis in recombinant Escherichia coli
journal, January 1999

Shi, Huidong; Nikawa, Junichi; Shimizu, Kazuyuki
Journal of Bioscience and Bioengineering, Vol. 87, Issue 5, p. 666-677
https://doi.org/10.1016/S1389-1723(99)80132-7

Modes of cyanobacterial carbon metabolism
journal, July 1983

Smith, A. J.
Annales de l'Institut Pasteur / Microbiologie, Vol. 134, Issue 1, p. 93-113
https://doi.org/10.1016/S0769-2609(83)80099-4

Poly(hydroxyalkanoate) in cyanobacteria: an overview
journal, December 1992

Stal, Lucas J.
FEMS Microbiology Letters, Vol. 103, Issue 2-4, p. 169-180
https://doi.org/10.1111/j.1574-6968.1992.tb05835.x

Phototrophic Prokaryotes: The Cyanobacteria
journal, October 1977

Stanier, R. Y.; Bazine, G. C.
Annual Review of Microbiology, Vol. 31, Issue 1
https://doi.org/10.1146/annurev.mi.31.100177.001301

Effect of increased PHA synthase activity on polyhydroxyalkanoates biosynthesis in Synechocystis sp. PCC6803
journal, April 2002

Sudesh, Kumar; Taguchi, Kazunori; Doi, Yoshiharu
International Journal of Biological Macromolecules, Vol. 30, Issue 2
https://doi.org/10.1016/S0141-8130(02)00010-7

Identification and Analysis of the Polyhydroxyalkanoate-Specific beta -Ketothiolase and Acetoacetyl Coenzyme A Reductase Genes in the Cyanobacterium Synechocystis sp. Strain PCC6803
journal, October 2000

Taroncher-Oldenburg, G.; Nishina, K.; Stephanopoulos, G.
Applied and Environmental Microbiology, Vol. 66, Issue 10
https://doi.org/10.1128/AEM.66.10.4440-4448.2000

Extraction of Lycopene from Tomato Skin with Supercritical Carbon Dioxide: Effect of Operating Conditions and Solubility Analysis
journal, July 2006

Topal, Ummihan; Sasaki, Mitsuru; Goto, Motonobu
Journal of Agricultural and Food Chemistry, Vol. 54, Issue 15
https://doi.org/10.1021/jf0606407

Use of electroporation to introduce biologically active foreign genes into primary rat hepatocytes.
journal, February 1986

Tur-Kaspa, R.; Teicher, L.; Levine, B. J.
Molecular and Cellular Biology, Vol. 6, Issue 2
https://doi.org/10.1128/MCB.6.2.716

Amplifying Genes: PCR and Its Alternatives
journal, April 1990

Van Brunt, Jennifer
Nature Biotechnology, Vol. 8, Issue 4
https://doi.org/10.1038/nbt0490-291

The three-dimensional structure of the cyanobacterium Synechocystis sp. PCC 6803
journal, December 2005

van de Meene, Allison M.L.; Hohmann-Marriott, Martin F.; Vermaas, Wim F.J.
Archives of Microbiology, Vol. 184, Issue 5, p. 259-270
https://doi.org/10.1007/s00203-005-0027-y

Occurrence of poly-beta-hydroxybutyrate in Spirulina species.
journal, May 1990

Vincenzini, M.; Sili, C.; de Philippis, R.
Journal of Bacteriology, Vol. 172, Issue 5
https://doi.org/10.1128/jb.172.5.2791-2792.1990

Transcriptional analysis of the isiAB operon in salt-stressed cells of the cyanobacterium Synechocystis sp. PCC 6803
journal, December 1998

Vinnemeier, Josef; Kunert, Anja; Hagemann, Martin
FEMS Microbiology Letters, Vol. 169, Issue 2, p. 323-330
https://doi.org/10.1111/j.1574-6968.1998.tb13336.x

Mechanism of lipid-body formation in prokaryotes: how bacteria fatten up
journal, December 2004

Wältermann, Marc; Hinz, Andreas; Robenek, Horst
Molecular Microbiology, Vol. 55, Issue 3, p. 750-763
https://doi.org/10.1111/j.1365-2958.2004.04441.x

Rhodococcus opacus strain PD630 as a new source of high-value single-cell oil? Isolation and characterization of triacylglycerols and other storage lipids
journal, May 2000

Kalscheuer, Rainer; Luftmann, Heinrich; Steinbüchel, Alexander
Microbiology, Vol. 146, Issue 5
https://doi.org/10.1099/00221287-146-5-1143

A Rapid Screen of Active Site Mutants in Glycinamide Ribonucleotide Transformylase ^†
journal, January 1996

Warren, Mark S.; Marolewski, Ariane E.; Benkovic, Stephen J.
Biochemistry, Vol. 35, Issue 27
https://doi.org/10.1021/bi9528715

Implantation of vascular grafts lined with genetically modified endothelial cells
journal, June 1989

Wilson, J.; Birinyi, L.; Salomon, R.
Science, Vol. 244, Issue 4910
https://doi.org/10.1126/science.2734614

Appearance of β-lactamase activity in animal cells upon liposome-mediated gene transfer
journal, July 1980

Tai-Kin, Wong; Nicolau, Claude; Hofschneider, Peter Hans
Gene, Vol. 10, Issue 2, p. 87-94
https://doi.org/10.1016/0378-1119(80)90126-2

Specificity of the nick-closing activity of bacteriophage T4 DNA ligase
journal, March 1989

Wu, Dan Y.; Wallace, R. Bruce
Gene, Vol. 76, Issue 2, p. 245-254
https://doi.org/10.1016/0378-1119(89)90165-0

Evidence for targeted gene delivery to Hep G2 hepatoma cells in vitro
journal, February 1988

Wu, George Y.; Wu, Catherine H.
Biochemistry, Vol. 27, Issue 3
https://doi.org/10.1021/bi00403a008

Accumulation of poly-β-hydroxybutyrate in cyanobacterium Synechocystis sp. PCC6803
journal, January 2001

Wu, G. F.; Wu, Q. Y.; Shen, Z. Y.
Bioresource Technology, Vol. 76, Issue 2, p. 85-90
https://doi.org/10.1016/S0960-8524(00)00099-7

Procaryotic complex I (NDH-1), an overview
journal, May 1998

Yagi, Takao; Yano, Takahiro; Di Bernardo, Salvatore
Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1364, Issue 2, p. 125-133
https://doi.org/10.1016/S0005-2728(98)00023-1

ATP-Binding Site of Human Brain Hexokinase As Studied by Molecular Modeling and Site-Directed Mutagenesis ^†
journal, January 1996

Zeng, Chenbo; Aleshin, Alexander E.; Hardie, Jason B.
Biochemistry, Vol. 35, Issue 40
https://doi.org/10.1021/bi960750e

A Method for Determination of Pyridine Nucleotides Using a Single Extract
journal, October 2000

Zhang, Zhiquan; Yu, Jia; Stanton, Robert C.
Analytical Biochemistry, Vol. 285, Issue 1
https://doi.org/10.1006/abio.2000.4701

Fermentation of 10% (w/v) Sugar to D(−)-Lactate by Engineered Escherichia coli B
journal, December 2005

Zhou, S.; Yomano, L. P.; Shanmugam, K. T.
Biotechnology Letters, Vol. 27, Issue 23-24
https://doi.org/10.1007/s10529-005-3899-7

The Arabidopsis thaliana TAG1 mutant has a mutation in a diacylglycerol acyltransferase gene
journal, September 1999

Zou, Jitao; Wei, Yangdou; Jako, Colette
The Plant Journal, Vol. 19, Issue 6
https://doi.org/10.1046/j.1365-313x.1999.00555.x

Phage Shock Protein PspA of Escherichia coli Relieves Saturation of Protein Export via the Tat Pathway
journal, December 2003

DeLisa, M. P.; Lee, P.; Palmer, T.
Journal of Bacteriology, Vol. 186, Issue 2
https://doi.org/10.1128/JB.186.2.366-373.2004

Chloroplast membrane transport: Interplay of prokaryotic and eukaryotic traits
journal, July 2005

Vothknecht, Ute C.; Soll, Jürgen
Gene, Vol. 354, p. 99-109
https://doi.org/10.1016/j.gene.2005.04.021

Similar Records in DOE Patents and OSTI.GOV collections:

Shuttle vector capable of transforming multiple genera of cyanobacteria

Patent Wang, Kui; Shi, Tuo

A plasmid vector for the production of compounds in cyanobacteria is described which is capable of being efficiently transformed to and replicating in a broad range of cyanobacterial species.
Full Text Available
Decreased light-harvesting antenna size in cyanobacteria

Patent Melis, Anastasios; Kirst, Henning

The invention provides methods and compositions for increasing photosynthetic efficiency and biomass production in cyanobacterial cultures by minimizing the phycobilisome light-harvesting antenna size through disruption of the phycocyanin-encoding CPC-operon.
Full Text Available
Production and secretion of glucose in photosynthetic prokaryotes (cyanobacteria)

Patent Nobles, Jr., David R. (Austin, TX), Brown, Jr., R. Malcolm (Austin, TX)

The present invention includes compositions and methods for making and using an isolated cyanobacterium that includes a portion of an exogenous bacterial cellulose operon sufficient to express bacterial cellulose, whereby the cyanobacterium produces extracellular glucose. The compositions and methods of the present invention may be used as a new global crop for the manufacture of cellulose, CO.sub.2 fixation, for the production of alternative sources of conventional cellulose as well as a biofuel and precursors thereof.
Full Text Available
Modified plants and methods for producing modified lignin by modulating expression of acyltransferases

Patent Loque, Dominique; Eudes, Aymerick Guillaume

The present invention provides for novel compositions and methods of producing modified lignin by modulating expression of acyltransferases.
Full Text Available
Genetically modified yeast species, and fermentation processes using genetically modified yeast

Patent Rajgarhia, Vineet; Koivuranta, Kari; Penttila, Merja; ...

Yeast cells are transformed with an exogenous xylose isomerase gene. Additional genetic modifications enhance the ability of the transformed cells to ferment xylose to ethanol or other desired fermentation products. Those modifications include deletion of non-specific or specific aldose reductase gene(s), deletion of xylitol dehydrogenase gene(s) and/or overexpression of xylulokinase.
Full Text Available

Similar Records

Title: Modified cyanobacteria

Abstract

Citation Formats

Protein tolerance to random amino acid change journal, June 2004

Transforming growth factor alpha: mutation of aspartic acid 47 and leucine 48 results in different biological activities. journal, March 1988

Functional Analysis of Conserved Histidines in ADP-Glucose Pyrophosphorylase from Escherichia coli journal, March 1998

Disentangling the perturbational effects of amino acid substitutions in the DNA-binding domain of p53 journal, February 1999

Sequence Analysis of the Genome of the Unicellular Cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence Features in the 1 Mb Region from Map Positions 64% to 92% of the Genome (Supplement) journal, January 1995

Polyhydroxyalkanoates: an overview journal, April 2003

An SmtB-like repressor from Synechocystis PCC 6803 regulates a zinc exporter journal, September 1998

Overproduction of Acetyl-CoA Carboxylase Activity Increases the Rate of Fatty Acid Biosynthesis in Escherichia coli journal, July 2000

A host-vector system for gene cloning in the cyanobacterium Synechocystis PCC 6803 journal, July 1986

Vipp1 deletion mutant of Synechocystis: A connection between bacterial phage shock and thylakoid biogenesis? journal, March 2001

VIPP1, a nuclear gene of Arabidopsis thaliana essential for thylakoid membrane formation journal, March 2001

Effects of co-expression of two higher plants genes ALD and TPI in Anabaena sp. PCC7120 on photosynthetic CO2 fixation journal, March 2005

Exogenous expression of the wheat chloroplastic fructose-1,6-bisphosphatase gene enhances photosynthesis in the transgenic cyanobacterium, Anabaena PCC7120 journal, May 2005

Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942 journal, November 1999

Distribution of the mevalonate and glyceraldehyde phosphate/pyruvate pathways for isoprenoid biosynthesis in unicellular algae and the cyanobacterium Synechocystis PCC 6714 journal, July 1998

Engineering a platform for photosynthetic isoprene production in cyanobacteria, using Synechocystis as the model organism journal, January 2010

Emissions of hydrocarbons from marine phytoplankton—Some results from controlled laboratory experiments journal, July 1996

First isolation of an isoprene synthase gene from poplar and successful expression of the gene in Escherichia coli journal, July 2001

Inactivation of sll1556 in Synechocystis Strain PCC 6803 Impairs Isoprenoid Biosynthesis from Pentose Phosphate Cycle Substrates In Vitro journal, July 2004

Gene expression and characterization of isoprene synthase from Populus alba journal, April 2005

Role of NtcB in Activation of Nitrate Assimilation Genes in the Cyanobacterium Synechocystis sp. Strain PCC 6803 journal, October 2001

Cyanobacterial Cell Inclusions journal, October 1984

Restoration of the wild-type locus in an RuBP carboxylase/oxygenase mutant of Synecbocystis PCC 6803 via targeted gene recombination journal, November 1992

Production of biodiesel from macroalgae by supercritical CO2 extraction and thermochemical liquefaction journal, November 2005

Photosynthetic accumulation of poly-(hydroxybutyrate) by cyanobacteria—the metabolism and potential for CO2 recycling journal, June 1999

Separation of Small Circular DNA Molecules from the Blue–green Alga Anacystis nidulans journal, August 1973

Blunt-end and single-strand ligations by Escherichia coli ligase: influence on an in vitro amplication scheme journal, April 1990

Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis journal, January 1981

Gene Transfer to the Desiccation-Tolerant Cyanobacterium Chroococcidiopsis journal, April 2001

Fast formation of high-purity methyl esters from vegetable oils journal, December 1998

Normalisation of sister chromatid exchange frequencies in Bloom's syndrome by euploid cell hybridisation journal, June 1979

In vitro scanning saturation mutagenesis of an antibody binding pocket journal, January 1997

Randomization of genes by PCR mutagenesis. journal, August 1992

A plasmid vector for isolation of strong promoters in Escherichia coli journal, August 1999

The occurrence of poly-β-hydroxybutyrate in the blue-green alga, Chlorogloea fritschii journal, June 1966

RNA splicing specificity determined by the coordinated action of RNA recognition motifs in SR proteins journal, April 1997

High-efficiency transformation of mammalian cells by plasmid DNA. journal, August 1987

Recovery in aqueous two-phase systems of lutein produced by the green microalga Chlorella protothecoides journal, July 2004

Succinate Dehydrogenase and Other Respiratory Pathways in Thylakoid Membranes of Synechocystis sp. Strain PCC 6803: Capacity Comparisons and Physiological Function journal, July 2001

Succinate:Quinol Oxidoreductases in the Cyanobacterium Synechocystis sp. Strain PCC 6803: Presence and Function in Metabolism and Electron Transport journal, February 2000

Insertional mutagenesis of the Drosophila genome with single P elements journal, March 1988

High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis journal, June 1989

Phospholipid:diacylglycerol acyltransferase: An enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants journal, May 2000

Factors affecting poly-β-hydroxybutyrate accumulation in cyanobacteria and in purple non-sulfur bacteria journal, December 1992

Glycogen and poly- -hydroxybutyrate synthesis in Spirulina maxima journal, August 1992

Ethanol production from cellulose by coupled saccharification/fermentation usingSaccharomyces cerevisiae and cellulase complex fromSclerotiun rolfsii UV-8 mutant journal, September 1992

Phycobilisomes of the Thermophilic Blue-Green alga Synechococcus Lividus journal, September 1971

Transfection of mammalian cells with plasmid DNA by scrape loading and sonication loading. journal, December 1987

Entrapment of a bacterial plasmid in phospholipid vesicles: potential for gene transfer. journal, July 1979

Gene transfer method for transient gene expression, stable transformation, and cotransformation of suspension cell cultures. journal, May 1985

A new technique for the assay of infectivity of human adenovirus 5 DNA journal, April 1973

Transformation in the cyanobacterium Synechocystis sp. 6803 journal, April 1982

Isothermal, in vitro amplification of nucleic acids by a multienzyme reaction modeled after retroviral replication. journal, March 1990

Radiation Response Characteristics of Human Cells in Vitro journal, June 1988

Translation of mRNA injected into Xenopus oocytes is specifically inhibited by antisense RNA journal, September 1985

Expression of a higher plant light-harvesting chlorophyll a/b-binding protein in Synechocystis sp. PCC 6803 journal, July 1999

Synechocystis sp. PCC6803 possesses a two-component polyhydroxyalkanoic acid synthase similar to that of anoxygenic purple sulfur bacteria journal, August 1998

Saturation Mutagenesis of the WSXWS Motif of the Erythropoietin Receptor journal, March 1996

Quinol and Cytochrome Oxidases in the Cyanobacterium Synechocystis sp. PCC 6803 † journal, December 1998

A strain of Synechocystis sp. PCC 6803 without photosynthetic oxygen evolution and respiratory oxygen consumption: implications for the study of cyclic photosynthetic electron transport journal, November 2001

Up-promoter mutations in the lpp gene of Escherichia coli journal, January 1985

Species variation in the specificity of ribulose biphosphate carboxylase/oxygenase journal, June 1981

Increased expression of DNA cointroduced with nuclear protein in adult rat liver journal, January 1989

High-Performance Liquid Chromatography Analysis of Oxidized and Reduced Pyridine Dinucleotides in Specific Brain Regions journal, July 1995

Transcription-based amplification system and detection of amplified human immunodeficiency virus type 1 with a bead-based sandwich hybridization format. journal, February 1989

Increased Production of Zeaxanthin and Other Pigments by Application of Genetic Engineering Techniques to Synechocystis sp. Strain PCC 6803 journal, January 2000

Effect of growth conditions on endo- and exopolymer biosynthesis in Anabaena cylindrica 10 C journal, June 1996

X-ray-Induced Changes in Gene lt Expression in Normal and r, Oncogene-Transformed Rat Cell Lines journal, November 1988

A ligase-mediated gene detection technique journal, August 1988

Internal Ribosomal Entry Site-Containing Retroviral Vectors with Green Fluorescent Protein and Drug Resistance Markers journal, May 1998

Purification and Characterization of the Poly(Hydroxyalkanoic Acid) Synthase from Chromatium vinosum and Localization of the Enzyme at the Surface of Poly(Hydroxyalkanoic Acid) Granules journal, November 1994

Control of polyhydroxyalkanoate synthesis in Azotobacter vinelandii strain UWD journal, April 1994

By-passing immunization: Human antibodies from V-gene libraries displayed on phage journal, December 1991

Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids. journal, March 1975

Inorganic Carbon Limitation and Light Control the Expression of Transcripts Related to the CO 2 -Concentrating Mechanism in the Cyanobacterium Synechocystis sp. Strain PCC6803 journal, April 2003

Regulation of glutamine synthetase activity in the unicellular cyanobacterium Synechocystis sp. strain PCC 6803 by the nitrogen source: effect of ammonium. journal, July 1991

Polyhydroxybutyrate Production from Carbon Dioxide by Cyanobacteria journal, January 2000

Protein tolerance to random amino acid change
journal, June 2004

Transforming growth factor alpha: mutation of aspartic acid 47 and leucine 48 results in different biological activities.
journal, March 1988

Functional Analysis of Conserved Histidines in ADP-Glucose Pyrophosphorylase from Escherichia coli
journal, March 1998

Disentangling the perturbational effects of amino acid substitutions in the DNA-binding domain of p53
journal, February 1999

Sequence Analysis of the Genome of the Unicellular Cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence Features in the 1 Mb Region from Map Positions 64% to 92% of the Genome (Supplement)
journal, January 1995

Polyhydroxyalkanoates: an overview
journal, April 2003

An SmtB-like repressor from Synechocystis PCC 6803 regulates a zinc exporter
journal, September 1998

Overproduction of Acetyl-CoA Carboxylase Activity Increases the Rate of Fatty Acid Biosynthesis in Escherichia coli
journal, July 2000

A host-vector system for gene cloning in the cyanobacterium Synechocystis PCC 6803
journal, July 1986

Vipp1 deletion mutant of Synechocystis: A connection between bacterial phage shock and thylakoid biogenesis?
journal, March 2001

VIPP1, a nuclear gene of Arabidopsis thaliana essential for thylakoid membrane formation
journal, March 2001

Effects of co-expression of two higher plants genes ALD and TPI in Anabaena sp. PCC7120 on photosynthetic CO₂ fixation
journal, March 2005

Exogenous expression of the wheat chloroplastic fructose-1,6-bisphosphatase gene enhances photosynthesis in the transgenic cyanobacterium, Anabaena PCC7120
journal, May 2005

Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942
journal, November 1999

Distribution of the mevalonate and glyceraldehyde phosphate/pyruvate pathways for isoprenoid biosynthesis in unicellular algae and the cyanobacterium Synechocystis PCC 6714
journal, July 1998

Engineering a platform for photosynthetic isoprene production in cyanobacteria, using Synechocystis as the model organism
journal, January 2010

Emissions of hydrocarbons from marine phytoplankton—Some results from controlled laboratory experiments
journal, July 1996

First isolation of an isoprene synthase gene from poplar and successful expression of the gene in Escherichia coli
journal, July 2001

Inactivation of sll1556 in Synechocystis Strain PCC 6803 Impairs Isoprenoid Biosynthesis from Pentose Phosphate Cycle Substrates In Vitro
journal, July 2004

Gene expression and characterization of isoprene synthase from Populus alba
journal, April 2005

Role of NtcB in Activation of Nitrate Assimilation Genes in the Cyanobacterium Synechocystis sp. Strain PCC 6803
journal, October 2001

Cyanobacterial Cell Inclusions
journal, October 1984

Restoration of the wild-type locus in an RuBP carboxylase/oxygenase mutant of Synecbocystis PCC 6803 via targeted gene recombination
journal, November 1992

Production of biodiesel from macroalgae by supercritical CO2 extraction and thermochemical liquefaction
journal, November 2005

Photosynthetic accumulation of poly-(hydroxybutyrate) by cyanobacteria—the metabolism and potential for CO₂ recycling
journal, June 1999

Separation of Small Circular DNA Molecules from the Blue–green Alga Anacystis nidulans
journal, August 1973

Blunt-end and single-strand ligations by Escherichia coli ligase: influence on an in vitro amplication scheme
journal, April 1990

Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis
journal, January 1981

Gene Transfer to the Desiccation-Tolerant Cyanobacterium Chroococcidiopsis
journal, April 2001

Fast formation of high-purity methyl esters from vegetable oils
journal, December 1998

Normalisation of sister chromatid exchange frequencies in Bloom's syndrome by euploid cell hybridisation
journal, June 1979

In vitro scanning saturation mutagenesis of an antibody binding pocket
journal, January 1997

Randomization of genes by PCR mutagenesis.
journal, August 1992

A plasmid vector for isolation of strong promoters in Escherichia coli
journal, August 1999

The occurrence of poly-β-hydroxybutyrate in the blue-green alga, Chlorogloea fritschii
journal, June 1966

RNA splicing specificity determined by the coordinated action of RNA recognition motifs in SR proteins
journal, April 1997

High-efficiency transformation of mammalian cells by plasmid DNA.
journal, August 1987

Recovery in aqueous two-phase systems of lutein produced by the green microalga Chlorella protothecoides
journal, July 2004

Succinate Dehydrogenase and Other Respiratory Pathways in Thylakoid Membranes of Synechocystis sp. Strain PCC 6803: Capacity Comparisons and Physiological Function
journal, July 2001

Succinate:Quinol Oxidoreductases in the Cyanobacterium Synechocystis sp. Strain PCC 6803: Presence and Function in Metabolism and Electron Transport
journal, February 2000

Insertional mutagenesis of the Drosophila genome with single P elements
journal, March 1988

High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis
journal, June 1989

Phospholipid:diacylglycerol acyltransferase: An enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants
journal, May 2000

Factors affecting poly-β-hydroxybutyrate accumulation in cyanobacteria and in purple non-sulfur bacteria
journal, December 1992

Glycogen and poly- -hydroxybutyrate synthesis in Spirulina maxima
journal, August 1992

Ethanol production from cellulose by coupled saccharification/fermentation usingSaccharomyces cerevisiae and cellulase complex fromSclerotiun rolfsii UV-8 mutant
journal, September 1992

Phycobilisomes of the Thermophilic Blue-Green alga Synechococcus Lividus
journal, September 1971

Transfection of mammalian cells with plasmid DNA by scrape loading and sonication loading.
journal, December 1987

Entrapment of a bacterial plasmid in phospholipid vesicles: potential for gene transfer.
journal, July 1979

Gene transfer method for transient gene expression, stable transformation, and cotransformation of suspension cell cultures.
journal, May 1985

A new technique for the assay of infectivity of human adenovirus 5 DNA
journal, April 1973

Transformation in the cyanobacterium Synechocystis sp. 6803
journal, April 1982

Isothermal, in vitro amplification of nucleic acids by a multienzyme reaction modeled after retroviral replication.
journal, March 1990

Radiation Response Characteristics of Human Cells in Vitro
journal, June 1988

Translation of mRNA injected into Xenopus oocytes is specifically inhibited by antisense RNA
journal, September 1985

Expression of a higher plant light-harvesting chlorophyll a/b-binding protein in Synechocystis sp. PCC 6803
journal, July 1999

Synechocystis sp. PCC6803 possesses a two-component polyhydroxyalkanoic acid synthase similar to that of anoxygenic purple sulfur bacteria
journal, August 1998

Saturation Mutagenesis of the WSXWS Motif of the Erythropoietin Receptor
journal, March 1996

Quinol and Cytochrome Oxidases in the Cyanobacterium Synechocystis sp. PCC 6803 ^†
journal, December 1998

A strain of Synechocystis sp. PCC 6803 without photosynthetic oxygen evolution and respiratory oxygen consumption: implications for the study of cyclic photosynthetic electron transport
journal, November 2001

Up-promoter mutations in the lpp gene of Escherichia coli
journal, January 1985

Species variation in the specificity of ribulose biphosphate carboxylase/oxygenase
journal, June 1981

Increased expression of DNA cointroduced with nuclear protein in adult rat liver
journal, January 1989

High-Performance Liquid Chromatography Analysis of Oxidized and Reduced Pyridine Dinucleotides in Specific Brain Regions
journal, July 1995

Transcription-based amplification system and detection of amplified human immunodeficiency virus type 1 with a bead-based sandwich hybridization format.
journal, February 1989

Increased Production of Zeaxanthin and Other Pigments by Application of Genetic Engineering Techniques to Synechocystis sp. Strain PCC 6803
journal, January 2000

Effect of growth conditions on endo- and exopolymer biosynthesis in Anabaena cylindrica 10 C
journal, June 1996

X-ray-Induced Changes in Gene lt Expression in Normal and r, Oncogene-Transformed Rat Cell Lines
journal, November 1988

A ligase-mediated gene detection technique
journal, August 1988

Internal Ribosomal Entry Site-Containing Retroviral Vectors with Green Fluorescent Protein and Drug Resistance Markers
journal, May 1998

Purification and Characterization of the Poly(Hydroxyalkanoic Acid) Synthase from Chromatium vinosum and Localization of the Enzyme at the Surface of Poly(Hydroxyalkanoic Acid) Granules
journal, November 1994

Control of polyhydroxyalkanoate synthesis in Azotobacter vinelandii strain UWD
journal, April 1994

By-passing immunization: Human antibodies from V-gene libraries displayed on phage
journal, December 1991

Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids.
journal, March 1975

Inorganic Carbon Limitation and Light Control the Expression of Transcripts Related to the CO ₂ -Concentrating Mechanism in the Cyanobacterium Synechocystis sp. Strain PCC6803
journal, April 2003

Regulation of glutamine synthetase activity in the unicellular cyanobacterium Synechocystis sp. strain PCC 6803 by the nitrogen source: effect of ammonium.
journal, July 1991

Polyhydroxybutyrate Production from Carbon Dioxide by Cyanobacteria
journal, January 2000

A thermophilic cyanobacterium, Synechococcus sp. MA19, capable of accumulating poly-β-hydroxybutyrate
journal, January 1996

Myxoxanthophyll Is Required for Normal Cell Wall Structure and Thylakoid Organization in the Cyanobacterium Synechocystis sp. Strain PCC 6803
journal, September 2005

Recombinant gene expression in vivo within endothelial cells of the arterial wall
journal, June 1989