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Title: Compositions and methods for improved protein production

Abstract

The present invention relates to the identification of novel nucleic acid sequences, designated herein as 7p, 8k, 7E, 9G, 8Q and 203, in a host cell which effect protein production. The present invention also provides host cells having a mutation or deletion of part or all of the gene encoding 7p, 8k, 7E, 9G, 8Q and 203, which are presented in FIG. 1, and are SEQ ID NOS.: 1-6, respectively. The present invention also provides host cells further comprising a nucleic acid encoding a desired heterologous protein such as an enzyme.

Inventors:
;
Issue Date:
Research Org.:
National Renewable Energy Laboratory (NREL), Golden, CO (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1133651
Patent Number(s):
8741654
Application Number:
13/494,889
Assignee:
Danisco US Inc. (Palo Alto, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
AC36-99GO10337
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Bodie, Elizabeth A., and Kim, Steve Sungjin. Compositions and methods for improved protein production. United States: N. p., 2014. Web.
Bodie, Elizabeth A., & Kim, Steve Sungjin. Compositions and methods for improved protein production. United States.
Bodie, Elizabeth A., and Kim, Steve Sungjin. Tue . "Compositions and methods for improved protein production". United States. https://www.osti.gov/servlets/purl/1133651.
@article{osti_1133651,
title = {Compositions and methods for improved protein production},
author = {Bodie, Elizabeth A. and Kim, Steve Sungjin},
abstractNote = {The present invention relates to the identification of novel nucleic acid sequences, designated herein as 7p, 8k, 7E, 9G, 8Q and 203, in a host cell which effect protein production. The present invention also provides host cells having a mutation or deletion of part or all of the gene encoding 7p, 8k, 7E, 9G, 8Q and 203, which are presented in FIG. 1, and are SEQ ID NOS.: 1-6, respectively. The present invention also provides host cells further comprising a nucleic acid encoding a desired heterologous protein such as an enzyme.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {6}
}

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    Works referencing / citing this record:

    Protease deficient filamentous fungal cells and methods of use thereof
    patent, February 2017