Title: Mutations and genetic targets for enhanced L-tyrosine production

Abstract

The invention relates to identification of mutations and genetic targets for enhanced L-tyrosine production, and bacterial strains capable of L-tyrosine production.

Inventors:

Santos, Christine; Stephanopoulos, Gregory

Issue Date:

2014-05-27

Research Org.:

Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

Sponsoring Org.:

USDOE

OSTI Identifier:

1132811

Patent Number(s):

8735132

Application Number:

13/101,579

Assignee:

Massachusetts Institute of Technology (Cambridge, MA)

Patent Classifications (CPCs):

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {

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C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

C12N1/20 - Bacteria {
C12N9/1077 - {Pentosyltransferases
C12N9/1096 - {transferring nitrogenous groups

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {

C12P13/004 - {Cyanohydrins}
C12P13/225 - {Tyrosine

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DOE Contract Number:  

FC36-07GO17058

Resource Type:

Patent

Resource Relation:

Patent File Date: 2011 May 05

Country of Publication:

United States

Language:

English

Subject:

59 BASIC BIOLOGICAL SCIENCES