Methods for targetted mutagenesis in gram-positive bacteria
Abstract
The present invention provides a method of targeted mutagenesis in Gram-positive bacteria. In particular, the present invention provides a method that effectively integrates a suicide integrative vector into a target gene in the chromosome of a Gram-positive bacterium, resulting in inactivation of the target gene.
- Inventors:
- Issue Date:
- Research Org.:
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1132802
- Patent Number(s):
- 8735160
- Application Number:
- 12/233,806
- Assignee:
- UT-Battelle, LLC (Oak Ridge, TN)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- AC05-000R22725
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2008 Sep 19
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Yang, Yunfeng. Methods for targetted mutagenesis in gram-positive bacteria. United States: N. p., 2014.
Web.
Yang, Yunfeng. Methods for targetted mutagenesis in gram-positive bacteria. United States.
Yang, Yunfeng. Tue .
"Methods for targetted mutagenesis in gram-positive bacteria". United States. https://www.osti.gov/servlets/purl/1132802.
@article{osti_1132802,
title = {Methods for targetted mutagenesis in gram-positive bacteria},
author = {Yang, Yunfeng},
abstractNote = {The present invention provides a method of targeted mutagenesis in Gram-positive bacteria. In particular, the present invention provides a method that effectively integrates a suicide integrative vector into a target gene in the chromosome of a Gram-positive bacterium, resulting in inactivation of the target gene.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {5}
}
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