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Title: Modulation of Rhamm (CD168) for selective adipose tissue development

Abstract

Herein is described the methods and compositions for modulation of Rhamm, also known as CD 186, and its effects on wound repair, muscle differentiation, bone density and adipogeneisis through its ability to regulate mesenchymal stem cell differentiation. Compositions and methods are provided for blocking Rhamm function for selectively increasing subcutaneous, but not, visceral fat. Compositions and methods for modulating Rhamm in wound repair are also described.

Inventors:
;
Issue Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1130537
Patent Number(s):
8715653
Application Number:
12/515,405
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
DOE Contract Number:  
AC02-05CH11231
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Turley, Eva A, and Bissell, Mina J. Modulation of Rhamm (CD168) for selective adipose tissue development. United States: N. p., 2014. Web.
Turley, Eva A, & Bissell, Mina J. Modulation of Rhamm (CD168) for selective adipose tissue development. United States.
Turley, Eva A, and Bissell, Mina J. Tue . "Modulation of Rhamm (CD168) for selective adipose tissue development". United States. https://www.osti.gov/servlets/purl/1130537.
@article{osti_1130537,
title = {Modulation of Rhamm (CD168) for selective adipose tissue development},
author = {Turley, Eva A and Bissell, Mina J},
abstractNote = {Herein is described the methods and compositions for modulation of Rhamm, also known as CD 186, and its effects on wound repair, muscle differentiation, bone density and adipogeneisis through its ability to regulate mesenchymal stem cell differentiation. Compositions and methods are provided for blocking Rhamm function for selectively increasing subcutaneous, but not, visceral fat. Compositions and methods for modulating Rhamm in wound repair are also described.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {5}
}

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