Modulation of Rhamm (CD168) for selective adipose tissue development
Abstract
Herein is described the methods and compositions for modulation of Rhamm, also known as CD 186, and its effects on wound repair, muscle differentiation, bone density and adipogeneisis through its ability to regulate mesenchymal stem cell differentiation. Compositions and methods are provided for blocking Rhamm function for selectively increasing subcutaneous, but not, visceral fat. Compositions and methods for modulating Rhamm in wound repair are also described.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1130537
- Patent Number(s):
- 8715653
- Application Number:
- 12/515,405
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
- DOE Contract Number:
- AC02-05CH11231
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES
Citation Formats
Turley, Eva A, and Bissell, Mina J. Modulation of Rhamm (CD168) for selective adipose tissue development. United States: N. p., 2014.
Web.
Turley, Eva A, & Bissell, Mina J. Modulation of Rhamm (CD168) for selective adipose tissue development. United States.
Turley, Eva A, and Bissell, Mina J. Tue .
"Modulation of Rhamm (CD168) for selective adipose tissue development". United States. https://www.osti.gov/servlets/purl/1130537.
@article{osti_1130537,
title = {Modulation of Rhamm (CD168) for selective adipose tissue development},
author = {Turley, Eva A and Bissell, Mina J},
abstractNote = {Herein is described the methods and compositions for modulation of Rhamm, also known as CD 186, and its effects on wound repair, muscle differentiation, bone density and adipogeneisis through its ability to regulate mesenchymal stem cell differentiation. Compositions and methods are provided for blocking Rhamm function for selectively increasing subcutaneous, but not, visceral fat. Compositions and methods for modulating Rhamm in wound repair are also described.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {5}
}
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