Dielectrokinetic chromatography and devices thereof
Disclosed herein are methods and devices for dielectrokinetic chromatography. As disclosed, the devices comprise microchannels having at least one perturber which produces a non-uniformity in a field spanning the width of the microchannel. The interaction of the field non-uniformity with a perturber produces a secondary flow which competes with a primary flow. By decreasing the size of the perturber the secondary flow becomes significant for particles/analytes in the nanometer-size range. Depending on the nature of a particle/analyte present in the fluid and its interaction with the primary flow and the secondary flow, the analyte may be retained or redirected. The composition of the primary flow can be varied to affect the magnitude of primary and/or secondary flows on the particles/analytes and thereby separate and concentrate it from other particles/analytes.
- Issue Date:
- OSTI Identifier:
- Sandia Corporation (Albuquerque, NM) SNL
- Patent Number(s):
- Application Number:
- Contract Number:
- Resource Relation:
- Patent File Date: 2008 May 29
- Research Org:
- Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
- Sponsoring Org:
- Country of Publication:
- United States
- 47 OTHER INSTRUMENTATION
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- Microelectronic Engineering, Vol. 4, Issue 1, p. 35-56
Silicate entrapped columns — new columns designed for capillary electrochromatography
journal, January 1999
- Chirica, Gabriela; Remcho, Vincent T.
- Electrophoresis, Vol. 20, Issue 1, p. 50-56
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