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Title: Process and targets for production of no-carrier-added radiotin

One embodiment of the present invention includes a process for production and recovery of no-carrier-added radioactive tin (NCA radiotin). An antimony target can be irradiated with a beam of accelerated particles forming NCA radiotin, followed by separation of the NCA radiotin from the irradiated target. The target is metallic Sb in a hermetically sealed shell. The shell can be graphite, molybdenum, or stainless steel. The irradiated target can be removed from the shell by chemical or mechanical means, and dissolved in an acidic solution. Sb can be removed from the dissolved irradiated target by extraction. NCA radiotin can be separated from the remaining Sb and other impurities using chromatography on silica gel sorbent. NCA tin-117m can be obtained from this process. NCA tin-117m can be used for labeling organic compounds and biological objects to be applied in medicine for imaging and therapy of various diseases.
Inventors:
; ; ; ; ; ;
Issue Date:
OSTI Identifier:
1129379
Assignee:
Brookhaven Science Associates, LLC (Upton, NY) BNL
Patent Number(s):
8,705,681
Application Number:
11/962,851
Contract Number:
AC02-98CH10886
Resource Relation:
Patent File Date: 2007 Dec 21
Research Org:
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
73 NUCLEAR PHYSICS AND RADIATION PHYSICS

Other works cited in this record:

Production of carrier-free 117mSn
journal, July 1984
  • Qaim, S. M.; Döhler, H.
  • The International Journal of Applied Radiation and Isotopes, Vol. 35, Issue 7, p. 645-650
  • DOI: 10.1016/0020-708X(84)90110-8

Improved specific activity of reactor produced 117mSn with the Szilard-Chalmers process
journal, September 1992
  • Mausner, L. F.; Mirzadeh, S.; Srivastava, S. C.
  • International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, Vol. 43, Issue 9, p. 1117-1122
  • DOI: 10.1016/0883-2889(92)90053-H

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