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Title: Xylose utilization in recombinant zymomonas

Abstract

Xylose-utilizing Zymomonas strains studied were found to accumulate ribulose when grown in xylose-containing media. Engineering these strains to increase ribose-5-phosphate isomerase activity led to reduced ribulose accumulation, improved growth, improved xylose utilization, and increased ethanol production.

Inventors:
; ; ; ;
Issue Date:
Research Org.:
E I du Pont de Nemours and Company, Wilmington, DE, USA
Sponsoring Org.:
USDOE
OSTI Identifier:
1128545
Patent Number(s):
8679822
Application Number:
13/161,734
Assignee:
E I du Pont de Nemours and Company (Wilmington, DE)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
DOE Contract Number:  
FC36-07GO17056
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Caimi, Perry G, McCole, Laura, Tao, Luan, Tomb, Jean-Francois, and Viitanen, Paul V. Xylose utilization in recombinant zymomonas. United States: N. p., 2014. Web.
Caimi, Perry G, McCole, Laura, Tao, Luan, Tomb, Jean-Francois, & Viitanen, Paul V. Xylose utilization in recombinant zymomonas. United States.
Caimi, Perry G, McCole, Laura, Tao, Luan, Tomb, Jean-Francois, and Viitanen, Paul V. Tue . "Xylose utilization in recombinant zymomonas". United States. https://www.osti.gov/servlets/purl/1128545.
@article{osti_1128545,
title = {Xylose utilization in recombinant zymomonas},
author = {Caimi, Perry G and McCole, Laura and Tao, Luan and Tomb, Jean-Francois and Viitanen, Paul V},
abstractNote = {Xylose-utilizing Zymomonas strains studied were found to accumulate ribulose when grown in xylose-containing media. Engineering these strains to increase ribose-5-phosphate isomerase activity led to reduced ribulose accumulation, improved growth, improved xylose utilization, and increased ethanol production.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {3}
}

Works referenced in this record:

Recombinant zymomonas for pentose fermentation
patent, May 1996


Pentose fermentation by recombinant zymomonas
patent, January 1998


Zymomonas pentose-sugar fermenting strains and uses thereof
patent, May 2007


Ethanol production using xylitol synthesis mutant of xylose-utilizing zymomonas
patent, June 2010


Xylitol synthesis mutant of xylose-utilizing zymomonas for ethanol production
patent, June 2010


Zymomonas with improved ethanol production in medium containing concentrated sugars and acetate
patent, September 2010


High expression Zymomonas promoters
patent, August 2011


Zymomonas with improved xylose utilization
patent, August 2011


Metabolic Engineering of Xylos Fermentation
patent-application, October 2008


Zymomonas with Improved Xylose Utilizations in Stress Conditions
patent-application, January 2011


Zymomonas with Improved Arabinose Utilization
patent-application, June 2011


Pentose metabolism in Zymomonas mobilis wild-type and recombinant strains
journal, December 1992


Genetic Engineering of Zymobacter palmae for Production of Ethanol from Xylose
journal, February 2007


Metabolic Engineering of a Pentose Metabolism Pathway in Ethanologenic Zymomonas mobilis
journal, January 1995


    Works referencing / citing this record:

    Xylose utilization in recombinant zymomonas
    patent, March 2014