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Title: Xylose utilization in recombinant zymomonas

Abstract

Xylose-utilizing Zymomonas strains studied were found to accumulate ribulose when grown in xylose-containing media. Engineering these strains to increase ribose-5-phosphate isomerase activity led to reduced ribulose accumulation, improved growth, improved xylose utilization, and increased ethanol production.

Inventors:
; ; ; ;
Issue Date:
Research Org.:
E I du Pont de Nemours and Company, Wilmington, DE, USA
Sponsoring Org.:
USDOE
OSTI Identifier:
1128545
Patent Number(s):
8,679,822
Application Number:
13/161,734
Assignee:
E I du Pont de Nemours and Company (Wilmington, DE)
DOE Contract Number:  
FC36-07GO17056
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Caimi, Perry G, McCole, Laura, Tao, Luan, Tomb, Jean-Francois, and Viitanen, Paul V. Xylose utilization in recombinant zymomonas. United States: N. p., 2014. Web.
Caimi, Perry G, McCole, Laura, Tao, Luan, Tomb, Jean-Francois, & Viitanen, Paul V. Xylose utilization in recombinant zymomonas. United States.
Caimi, Perry G, McCole, Laura, Tao, Luan, Tomb, Jean-Francois, and Viitanen, Paul V. Tue . "Xylose utilization in recombinant zymomonas". United States. https://www.osti.gov/servlets/purl/1128545.
@article{osti_1128545,
title = {Xylose utilization in recombinant zymomonas},
author = {Caimi, Perry G and McCole, Laura and Tao, Luan and Tomb, Jean-Francois and Viitanen, Paul V},
abstractNote = {Xylose-utilizing Zymomonas strains studied were found to accumulate ribulose when grown in xylose-containing media. Engineering these strains to increase ribose-5-phosphate isomerase activity led to reduced ribulose accumulation, improved growth, improved xylose utilization, and increased ethanol production.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {3}
}

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Works referenced in this record:

Metabolic Engineering of Xylos Fermentation
patent-application, October 2008


Pentose metabolism in Zymomonas mobilis wild-type and recombinant strains
journal, December 1992

  • Feldmann, SigrunD.; Sahm, Hermann; Sprenger, GeorgA.
  • Applied Microbiology and Biotechnology, Vol. 38, Issue 3
  • DOI: 10.1007/BF00170086

Genetic Engineering of Zymobacter palmae for Production of Ethanol from Xylose
journal, February 2007

  • Yanase, H.; Sato, D.; Yamamoto, K.
  • Applied and Environmental Microbiology, Vol. 73, Issue 8
  • DOI: 10.1128/AEM.02302-06

Metabolic Engineering of a Pentose Metabolism Pathway in Ethanologenic Zymomonas mobilis
journal, January 1995