Transformation of gram positive bacteria by sonoporation
Abstract
The present invention provides a sonoporation-based method that can be universally applied for delivery of compounds into Gram positive bacteria. Gram positive bacteria which can be transformed by sonoporation include, for example, Bacillus, Streptococcus, Acetobacterium, and Clostridium. Compounds which can be delivered into Gram positive bacteria via sonoporation include nucleic acids (DNA or RNA), proteins, lipids, carbohydrates, viruses, small organic and inorganic molecules, and nano-particles.
- Inventors:
- Issue Date:
- Research Org.:
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1126704
- Patent Number(s):
- 8669085
- Application Number:
- 12/657,885
- Assignee:
- UT-Battelle, LLC (Oak Ridge, TN)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- AC05-000R22725
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Yang, Yunfeng, and Li, Yongchao. Transformation of gram positive bacteria by sonoporation. United States: N. p., 2014.
Web.
Yang, Yunfeng, & Li, Yongchao. Transformation of gram positive bacteria by sonoporation. United States.
Yang, Yunfeng, and Li, Yongchao. Tue .
"Transformation of gram positive bacteria by sonoporation". United States. https://www.osti.gov/servlets/purl/1126704.
@article{osti_1126704,
title = {Transformation of gram positive bacteria by sonoporation},
author = {Yang, Yunfeng and Li, Yongchao},
abstractNote = {The present invention provides a sonoporation-based method that can be universally applied for delivery of compounds into Gram positive bacteria. Gram positive bacteria which can be transformed by sonoporation include, for example, Bacillus, Streptococcus, Acetobacterium, and Clostridium. Compounds which can be delivered into Gram positive bacteria via sonoporation include nucleic acids (DNA or RNA), proteins, lipids, carbohydrates, viruses, small organic and inorganic molecules, and nano-particles.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {3}
}
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