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Title: Transformation of gram positive bacteria by sonoporation

Abstract

The present invention provides a sonoporation-based method that can be universally applied for delivery of compounds into Gram positive bacteria. Gram positive bacteria which can be transformed by sonoporation include, for example, Bacillus, Streptococcus, Acetobacterium, and Clostridium. Compounds which can be delivered into Gram positive bacteria via sonoporation include nucleic acids (DNA or RNA), proteins, lipids, carbohydrates, viruses, small organic and inorganic molecules, and nano-particles.

Inventors:
;
Issue Date:
Research Org.:
ORNL (Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States))
Sponsoring Org.:
USDOE
OSTI Identifier:
1126704
Patent Number(s):
8,669,085
Application Number:
12/657,885
Assignee:
UT-Battelle, LLC (Oak Ridge, TN)
DOE Contract Number:  
AC05-000R22725
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Yang, Yunfeng, and Li, Yongchao. Transformation of gram positive bacteria by sonoporation. United States: N. p., 2014. Web.
Yang, Yunfeng, & Li, Yongchao. Transformation of gram positive bacteria by sonoporation. United States.
Yang, Yunfeng, and Li, Yongchao. Tue . "Transformation of gram positive bacteria by sonoporation". United States. https://www.osti.gov/servlets/purl/1126704.
@article{osti_1126704,
title = {Transformation of gram positive bacteria by sonoporation},
author = {Yang, Yunfeng and Li, Yongchao},
abstractNote = {The present invention provides a sonoporation-based method that can be universally applied for delivery of compounds into Gram positive bacteria. Gram positive bacteria which can be transformed by sonoporation include, for example, Bacillus, Streptococcus, Acetobacterium, and Clostridium. Compounds which can be delivered into Gram positive bacteria via sonoporation include nucleic acids (DNA or RNA), proteins, lipids, carbohydrates, viruses, small organic and inorganic molecules, and nano-particles.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {3}
}

Patent:

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