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Title: Selective incorporation of 5-hydroxytryptophan into proteins in mammalian cells

This invention provides methods and compositions for incorporation of an unnatural amino acid into a peptide using an orthogonal aminoacyl tRNA synthetase/tRNA pair. In particular, an orthogonal pair is provided to incorporate 5-hydroxy-L-tryptophan in a position encoded by an opal mutation.
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Issue Date:
OSTI Identifier:
The Scripps Research Institute (La Jolla, CA) OAK
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Research Org:
The Scripps Research Institute, La Jolla, CA, USA
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Country of Publication:
United States

Works referenced in this record:

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