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Title: Compositions, devices and methods for SERS and LSPR

Abstract

The present invention relates to compositions, devices and methods for detecting microorganisms (e.g., anthrax). In particular, the present invention provides portable, surface-enhanced Raman biosensors, and associated substrates, and methods of using the same, for use in rapidly detecting and identifying microorganisms (e.g., anthrax).

Inventors:
; ; ; ; ; ; ; ; ;
Issue Date:
Research Org.:
ANL (Argonne National Laboratory (ANL), Argonne, IL (United States))
Sponsoring Org.:
USDOE
OSTI Identifier:
1117699
Patent Number(s):
8,628,727
Application Number:
11/846,352
Assignee:
Northwestern University (Evanston, IL)
DOE Contract Number:  
FG02-03ER15457; W-31-109-ENG-38; AC02-06CH11357
Resource Type:
Patent
Resource Relation:
Patent File Date: 2007 Aug 28
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Citation Formats

Van Duyne, Richard P, Zhang, Xiaoyu, Zhao, Jing, Whitney, Alyson V, Elam, Jeffrey W, Schatz, George C, Stair, Peter C, Zou, Shengli, Young, Matthew, and Lyandres, Olga. Compositions, devices and methods for SERS and LSPR. United States: N. p., 2014. Web.
Van Duyne, Richard P, Zhang, Xiaoyu, Zhao, Jing, Whitney, Alyson V, Elam, Jeffrey W, Schatz, George C, Stair, Peter C, Zou, Shengli, Young, Matthew, & Lyandres, Olga. Compositions, devices and methods for SERS and LSPR. United States.
Van Duyne, Richard P, Zhang, Xiaoyu, Zhao, Jing, Whitney, Alyson V, Elam, Jeffrey W, Schatz, George C, Stair, Peter C, Zou, Shengli, Young, Matthew, and Lyandres, Olga. Tue . "Compositions, devices and methods for SERS and LSPR". United States. https://www.osti.gov/servlets/purl/1117699.
@article{osti_1117699,
title = {Compositions, devices and methods for SERS and LSPR},
author = {Van Duyne, Richard P and Zhang, Xiaoyu and Zhao, Jing and Whitney, Alyson V and Elam, Jeffrey W and Schatz, George C and Stair, Peter C and Zou, Shengli and Young, Matthew and Lyandres, Olga},
abstractNote = {The present invention relates to compositions, devices and methods for detecting microorganisms (e.g., anthrax). In particular, the present invention provides portable, surface-enhanced Raman biosensors, and associated substrates, and methods of using the same, for use in rapidly detecting and identifying microorganisms (e.g., anthrax).},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {1}
}

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Works referenced in this record:

Atomic force microscopy and surface‐enhanced Raman spectroscopy. I. Ag island films and Ag film over polymer nanosphere surfaces supported on glass
journal, August 1993

  • Van Duyne, R. P.; Hulteen, J. C.; Treichel, D. A.
  • The Journal of Chemical Physics, Vol. 99, Issue 3
  • DOI: 10.1063/1.465276

Localized Surface Plasmon Resonance Nanosensor:  A High-Resolution Distance-Dependence Study Using Atomic Layer Deposition
journal, November 2005

  • Whitney, Alyson V.; Elam, Jeffrey W.; Zou, Shengli
  • The Journal of Physical Chemistry B, Vol. 109, Issue 43
  • DOI: 10.1021/jp0540656

Vibrational spectra and structure of crystalline dipicolinic acid and calcium dipicolinate trihydrate
journal, January 1980


Octadecylthiol-modified surface-enhanced Raman spectroscopy substrates: a new method for the detection of aromatic compounds
journal, October 1992

  • Carron, Keith; Peitersen, Laura; Lewis, Mary
  • Environmental Science & Technology, Vol. 26, Issue 10
  • DOI: 10.1021/es00034a011

Reagentless Identification of Single Bacterial Spores in Aqueous Solution by Confocal Laser Tweezers Raman Spectroscopy
journal, February 2004

  • Chan, J. W.; Esposito, A. P.; Talley, C. E.
  • Analytical Chemistry, Vol. 76, Issue 3
  • DOI: 10.1021/ac0350155

Metal Film over Nanosphere (MFON) Electrodes for Surface-Enhanced Raman Spectroscopy (SERS):  Improvements in Surface Nanostructure Stability and Suppression of Irreversible Loss
journal, January 2002

  • Dick, Lisa A.; McFarland, Adam D.; Haynes, Christy L.
  • The Journal of Physical Chemistry B, Vol. 106, Issue 4
  • DOI: 10.1021/jp013638l

Introductory Lecture : Surface enhanced Raman spectroscopy: new materials, concepts, characterization tools, and applications
journal, January 2006

  • Dieringer, Jon A.; McFarland, Adam D.; Shah, Nilam C.
  • Faraday Discuss., Vol. 132
  • DOI: 10.1039/B513431P

Low-Level Detection of Viral Pathogens by a Surface-Enhanced Raman Scattering Based Immunoassay
journal, October 2005

  • Driskell, Jeremy D.; Kwarta, Karen M.; Lipert, Robert J.
  • Analytical Chemistry, Vol. 77, Issue 19
  • DOI: 10.1021/ac0504159

Viscous flow reactor with quartz crystal microbalance for thin film growth by atomic layer deposition
journal, August 2002

  • Elam, J. W.; Groner, M. D.; George, S. M.
  • Review of Scientific Instruments, Vol. 73, Issue 8, p. 2981-2987
  • DOI: 10.1063/1.1490410

Rapid Dipicolinic Acid Extraction from Bacillus Spores Detected by Surface-Enhanced Raman Spectroscopy
journal, March 2004


PCR Assay To Detect Bacillus anthracis Spores in Heat-Treated Specimens
journal, February 2003


Detection of the Dipicolinic Acid Biomarker in Bacillus Spores Using Curie-Point Pyrolysis Mass Spectrometry and Fourier Transform Infrared Spectroscopy
journal, January 2000

  • Goodacre, Royston; Shann, Beverley; Gilbert, Richard J.
  • Analytical Chemistry, Vol. 72, Issue 1
  • DOI: 10.1021/ac990661i

Plasmon-Sampled Surface-Enhanced Raman Excitation Spectroscopy
journal, July 2003

  • Haynes, Christy L.; Van Duyne, Richard P.
  • The Journal of Physical Chemistry B, Vol. 107, Issue 30
  • DOI: 10.1021/jp027749b

Nanosphere lithography: A materials general fabrication process for periodic particle array surfaces
journal, May 1995

  • Hulteen, John C.; Van Duyne, Richard P.
  • Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films, Vol. 13, Issue 3, p. 1553-1558
  • DOI: 10.1116/1.579726

Detection of the Bacillus anthracis gyrA Gene by Using a Minor Groove Binder Probe
journal, January 2004


Discrimination of Bacteria Using Surface-Enhanced Raman Spectroscopy
journal, January 2004

  • Jarvis, Roger M.; Goodacre, Royston
  • Analytical Chemistry, Vol. 76, Issue 1
  • DOI: 10.1021/ac034689c

Sticking Probabilities in Adsorption of Alkanethiols from Liquid Ethanol Solution onto Gold
journal, November 2000

  • Jung, Linda S.; Campbell, Charles. T.
  • The Journal of Physical Chemistry B, Vol. 104, Issue 47
  • DOI: 10.1021/jp001649t

Sticking Probabilities in Adsorption from Liquid Solutions: Alkylthiols on Gold
journal, May 2000


Performance Assessment of Three Commercial Assays for Direct Detection of Bacillus anthracis Spores
journal, July 2003


Surface-Enhanced Raman Scattering Detected Temperature Programmed Desorption:  Optical Properties, Nanostructure, and Stability of Silver Film over SiO 2 Nanosphere Surfaces
journal, July 2001

  • Litorja, Maritoni; Haynes, Christy L.; Haes, Amanda J.
  • The Journal of Physical Chemistry B, Vol. 105, Issue 29
  • DOI: 10.1021/jp010333y

Wavelength-Scanned Surface-Enhanced Raman Excitation Spectroscopy
journal, June 2005

  • McFarland, Adam D.; Young, Matthew A.; Dieringer, Jon A.
  • The Journal of Physical Chemistry B, Vol. 109, Issue 22
  • DOI: 10.1021/jp050508u

Detection of Nitrate and Sulfate Anions by Normal Raman Spectroscopy and SERS of Cationic-Coated, Silver Substrates
journal, August 2000


Enhanced spore detection using dipicolinate extraction techniques
journal, March 2002

  • Pellegrino, Paul M.; Fell, Nicholas F.; Gillespie, James B.
  • Analytica Chimica Acta, Vol. 455, Issue 2, p. 167-177
  • DOI: 10.1016/S0003-2670(01)01613-0

Electromagnetic Mechanism of Surface-Enhanced Spectroscopy
book, June 2006

  • Schatz, George C.; Van Duyne, Richard P.; Chalmers, John M.
  • Handbook of Vibrational Spectroscopy
  • DOI: 10.1002/0470027320.s0601

Identification of Bacterial Spores Using Statistical Analysis of Fourier Transform Infrared Photoacoustic Spectroscopy Data
journal, August 2003

  • Thompson, Sandra E.; Foster, Nancy S.; Johnson, Timothy J.
  • Applied Spectroscopy, Vol. 57, Issue 8
  • DOI: 10.1366/000370203322258832

A Glucose Biosensor Based on Surface-Enhanced Raman Scattering:  Improved Partition Layer, Temporal Stability, Reversibility, and Resistance to Serum Protein Interference
journal, January 2004

  • Yonzon, Chanda Ranjit; Haynes, Christy L.; Zhang, Xiaoyu
  • Analytical Chemistry, Vol. 76, Issue 1
  • DOI: 10.1021/ac035134k

An electrochemical surface-enhanced Raman spectroscopy approach to anthrax detection
conference, November 2003

  • Zhang, Xiaoyu; Yonzon, Chanda R.; Van Duyne, Richard P.
  • Optical Science and Technology, SPIE's 48th Annual Meeting, SPIE Proceedings
  • DOI: 10.1117/12.508519

Rapid Detection of an Anthrax Biomarker by Surface-Enhanced Raman Spectroscopy
journal, March 2005

  • Zhang, Xiaoyu; Young, Matthew A.; Lyandres, Olga
  • Journal of the American Chemical Society, Vol. 127, Issue 12
  • DOI: 10.1021/ja043623b