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Title: Group specific internal standard technology (GSIST) for simultaneous identification and quantification of small molecules

Reagents and methods are provided that permit simultaneous analysis of multiple diverse small molecule analytes present in a complex mixture. Samples are labeled with chemically identical but isotopically distince forms of the labeling reagent, and analyzed using mass spectrometry. A single reagent simultaneously derivatizes multiple small molecule analytes having different reactive functional groups.
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Purdue Research Foundation (West Lafayette, IN) GFO
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Resource Relation:
Patent File Date: 2009 May 01
Research Org:
Purdue Research Foundation, West Lafayette, IN, USA
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Country of Publication:
United States

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