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Title: Methylocystis strain SB2 materials and methods

Abstract

The present disclosures provides isolated or purified compounds, each of which bind to a metal atom. Generally, the compounds are small in size (e.g., molecular weight of less than about 1 kDa) and peptidic in nature, inasmuch as the compounds comprise amino acids. In some embodiments, the compound comprises a structure of Formula I; M.sub.1-P.sub.1-M.sub.2-P.sub.2 wherein each of P.sub.1 and P.sub.2 is a peptide comprising at least two amino acids, M.sub.1 is a first metal binding moiety comprising a substituted imidazolone ring, M.sub.2 is a second metal binding moiety comprising a substituted oxazolone ring, and wherein M.sub.1 and M.sub.2 bind to a single metal atom. Also provided are related complexes, conjugates, cells which synthesize the compounds of the present disclosures, substantially homogenous cultures thereof, kits and compositions, and methods of making or using the materials of the present disclosures.

Inventors:
; ; ; ; ; ; ;
Issue Date:
Research Org.:
Iowa State University Research Foundation, Inc. (Ames, IA)
Sponsoring Org.:
USDOE
OSTI Identifier:
1117663
Patent Number(s):
8,629,239
Application Number:
13/198,669
Assignee:
Iowa State University Research Foundation, Inc. (Ames, IA); The Regents of the University of Michigan (Ann Arbor, MI); WiSys Technology Foundation (Madison, WI)
DOE Contract Number:  
FC26-05NT42431
Resource Type:
Patent
Resource Relation:
Patent File Date: 2011 Aug 04
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Semrau, Jeremy D, Gallagher, Warren, Yoon, Sukhwan, Im, Jeongdae, DiSpririto, Alan A, Lee, Sung-Woo, Hartsel, Scott, and McEllistrem, Marcus T. Methylocystis strain SB2 materials and methods. United States: N. p., 2014. Web.
Semrau, Jeremy D, Gallagher, Warren, Yoon, Sukhwan, Im, Jeongdae, DiSpririto, Alan A, Lee, Sung-Woo, Hartsel, Scott, & McEllistrem, Marcus T. Methylocystis strain SB2 materials and methods. United States.
Semrau, Jeremy D, Gallagher, Warren, Yoon, Sukhwan, Im, Jeongdae, DiSpririto, Alan A, Lee, Sung-Woo, Hartsel, Scott, and McEllistrem, Marcus T. Tue . "Methylocystis strain SB2 materials and methods". United States. https://www.osti.gov/servlets/purl/1117663.
@article{osti_1117663,
title = {Methylocystis strain SB2 materials and methods},
author = {Semrau, Jeremy D and Gallagher, Warren and Yoon, Sukhwan and Im, Jeongdae and DiSpririto, Alan A and Lee, Sung-Woo and Hartsel, Scott and McEllistrem, Marcus T},
abstractNote = {The present disclosures provides isolated or purified compounds, each of which bind to a metal atom. Generally, the compounds are small in size (e.g., molecular weight of less than about 1 kDa) and peptidic in nature, inasmuch as the compounds comprise amino acids. In some embodiments, the compound comprises a structure of Formula I; M.sub.1-P.sub.1-M.sub.2-P.sub.2 wherein each of P.sub.1 and P.sub.2 is a peptide comprising at least two amino acids, M.sub.1 is a first metal binding moiety comprising a substituted imidazolone ring, M.sub.2 is a second metal binding moiety comprising a substituted oxazolone ring, and wherein M.sub.1 and M.sub.2 bind to a single metal atom. Also provided are related complexes, conjugates, cells which synthesize the compounds of the present disclosures, substantially homogenous cultures thereof, kits and compositions, and methods of making or using the materials of the present disclosures.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {1}
}

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