Title: Methylocystis strain SB2 materials and methods

Abstract

The present disclosures provides isolated or purified compounds, each of which bind to a metal atom. Generally, the compounds are small in size (e.g., molecular weight of less than about 1 kDa) and peptidic in nature, inasmuch as the compounds comprise amino acids. In some embodiments, the compound comprises a structure of Formula I; M.sub.1-P.sub.1-M.sub.2-P.sub.2 wherein each of P.sub.1 and P.sub.2 is a peptide comprising at least two amino acids, M.sub.1 is a first metal binding moiety comprising a substituted imidazolone ring, M.sub.2 is a second metal binding moiety comprising a substituted oxazolone ring, and wherein M.sub.1 and M.sub.2 bind to a single metal atom. Also provided are related complexes, conjugates, cells which synthesize the compounds of the present disclosures, substantially homogenous cultures thereof, kits and compositions, and methods of making or using the materials of the present disclosures.

Inventors:

Semrau, Jeremy D; Gallagher, Warren; Yoon, Sukhwan; Im, Jeongdae; DiSpririto, Alan A; Lee, Sung-Woo; Hartsel, Scott; McEllistrem, Marcus T

Issue Date:

2014-01-14

Research Org.:

Iowa State University Research Foundation, Inc. (Ames, IA)

Sponsoring Org.:

USDOE

OSTI Identifier:

1117663

Patent Number(s):

8629239

Application Number:

13/198,669

Assignee:

Iowa State University Research Foundation, Inc. (Ames, IA); The Regents of the University of Michigan (Ann Arbor, MI); WiSys Technology Foundation (Madison, WI)

Patent Classifications (CPCs):

B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES

C - CHEMISTRY C02 - TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE C02F - TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE

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B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES

B82Y40/00 - Manufacture or treatment of nanostructures

C - CHEMISTRY C02 - TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE C02F - TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE

C02F1/683 - {by addition of complex-forming compounds}
C02F1/72 - by oxidation {
C02F2101/10 - Inorganic compounds
C02F2101/20 - Heavy metals or heavy metal compounds
C02F2101/22 - Chromium or chromium compounds, e.g. chromates
C02F3/341 - {Consortia of bacteria}

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07D - HETEROCYCLIC COMPOUNDS

C07D413/12 - linked by a chain containing hetero atoms as chain links

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {

C12P13/04 - Alpha- or beta- amino acids {
C12P3/00 - Preparation of elements or inorganic compounds except carbon dioxide {

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DOE Contract Number:  

FC26-05NT42431

Resource Type:

Patent

Resource Relation:

Patent File Date: 2011 Aug 04

Country of Publication:

United States

Language:

English

Subject:

59 BASIC BIOLOGICAL SCIENCES