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Title: Saccharide antifreeze compositions

Abstract

The invention provides an antifreeze glycolipid compounds and composition comprising a polysaccharide moiety of Formula I; ##STR00001## wherein D-Manp represents a D-mannopyranose moiety, D-Xylp represents a D-xylopyranose moiety, and n is about 5 to about 70; and one or more lipid moieties covalently linked to the polysaccharide moiety of Formula I or electrostatically associated with the polysaccaride moiety for Formula I. The antifreeze glycolipid compounds and compositions can be used for a variety of industrial, agricultural, medical, and cosmetic applications where recrystallization-inhibition, cyroprotection, or cryopreservation is desired. The antifreeze glycolipid compounds or compositions can be used as, for example, as cryoprotectants for tissue preservation and transplantation, improving the texture of processed frozen food and frozen meats, frostbit protection, crop protection, and green alternatives for land vehicle antifreeze and aircraft de-icing.

Inventors:
; ;
Issue Date:
Research Org.:
University of Notre Dame Du Lac, Notre Dame, IN, USA
Sponsoring Org.:
USDOE
OSTI Identifier:
1109476
Patent Number(s):
8604002
Application Number:
13/135,065
Assignee:
University of Notre Dame Du Lac (Notre Dame, IN)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C08 - ORGANIC MACROMOLECULAR COMPOUNDS C08B - POLYSACCHARIDES
DOE Contract Number:  
FG09-93ER20097
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Walters, Kent, Duman, John G, and Serianni, Anthony S. Saccharide antifreeze compositions. United States: N. p., 2013. Web.
Walters, Kent, Duman, John G, & Serianni, Anthony S. Saccharide antifreeze compositions. United States.
Walters, Kent, Duman, John G, and Serianni, Anthony S. Tue . "Saccharide antifreeze compositions". United States. https://www.osti.gov/servlets/purl/1109476.
@article{osti_1109476,
title = {Saccharide antifreeze compositions},
author = {Walters, Kent and Duman, John G and Serianni, Anthony S},
abstractNote = {The invention provides an antifreeze glycolipid compounds and composition comprising a polysaccharide moiety of Formula I; ##STR00001## wherein D-Manp represents a D-mannopyranose moiety, D-Xylp represents a D-xylopyranose moiety, and n is about 5 to about 70; and one or more lipid moieties covalently linked to the polysaccharide moiety of Formula I or electrostatically associated with the polysaccaride moiety for Formula I. The antifreeze glycolipid compounds and compositions can be used for a variety of industrial, agricultural, medical, and cosmetic applications where recrystallization-inhibition, cyroprotection, or cryopreservation is desired. The antifreeze glycolipid compounds or compositions can be used as, for example, as cryoprotectants for tissue preservation and transplantation, improving the texture of processed frozen food and frozen meats, frostbit protection, crop protection, and green alternatives for land vehicle antifreeze and aircraft de-icing.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Dec 10 00:00:00 EST 2013},
month = {Tue Dec 10 00:00:00 EST 2013}
}

Works referenced in this record:

A nonprotein thermal hysteresis-producing xylomannan antifreeze in the freeze-tolerant Alaskan beetle Upis ceramboides
journal, November 2009


Rhamnolipids: diversity of structures, microbial origins and roles
journal, March 2010