Catheter based mid-infrared reflectance and reflectance generated absorption spectroscopy
Abstract
A method of characterizing conditions in a tissue, by (a) providing a catheter that has a light source that emits light in selected wavenumbers within the range of mid-IR spectrum; (b) directing the light from the catheter to an area of tissue at a location inside a blood vessel of a subject; (c) collecting light reflected from the location and generating a reflectance spectra; and (d) comparing the reflectance spectra to a reference spectra of normal tissue, whereby a location having an increased number of absorbance peaks at said selected wavenumbers indicates a tissue inside the blood vessel containing a physiological marker for atherosclerosis.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1107628
- Patent Number(s):
- 8571640
- Application Number:
- 10/582,422
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC03-76SF00098
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES
Citation Formats
Holman, Hoi-Ying N. Catheter based mid-infrared reflectance and reflectance generated absorption spectroscopy. United States: N. p., 2013.
Web.
Holman, Hoi-Ying N. Catheter based mid-infrared reflectance and reflectance generated absorption spectroscopy. United States.
Holman, Hoi-Ying N. Tue .
"Catheter based mid-infrared reflectance and reflectance generated absorption spectroscopy". United States. https://www.osti.gov/servlets/purl/1107628.
@article{osti_1107628,
title = {Catheter based mid-infrared reflectance and reflectance generated absorption spectroscopy},
author = {Holman, Hoi-Ying N},
abstractNote = {A method of characterizing conditions in a tissue, by (a) providing a catheter that has a light source that emits light in selected wavenumbers within the range of mid-IR spectrum; (b) directing the light from the catheter to an area of tissue at a location inside a blood vessel of a subject; (c) collecting light reflected from the location and generating a reflectance spectra; and (d) comparing the reflectance spectra to a reference spectra of normal tissue, whereby a location having an increased number of absorbance peaks at said selected wavenumbers indicates a tissue inside the blood vessel containing a physiological marker for atherosclerosis.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Oct 29 00:00:00 EDT 2013},
month = {Tue Oct 29 00:00:00 EDT 2013}
}
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