System and method for measuring particles in a sample stream of a flow cytometer using a low power laser source
Abstract
A system and method for analyzing a particle in a sample stream of a flow cytometer or the like. The system has a light source, such as a laser pointer module, for generating a low powered light beam and a fluidics apparatus which is configured to transport particles in the sample stream at substantially low velocity through the light beam for interrogation. Detectors, such as photomultiplier tubes, are configured to detect optical signals generated in response to the light beam impinging the particles. Signal conditioning circuitry is connected to each of the detectors to condition each detector output into electronic signals for processing and is designed to have a limited frequency response to filter high frequency noise from the detector output signals.
- Inventors:
- Issue Date:
- Research Org.:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1107599
- Patent Number(s):
- 8564776
- Application Number:
- 12/903,003
- Assignee:
- Los Alamos National Security, LLC (Los Alamos, NM)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC52-06NA25396
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Graves, Steven W, and Habbersett, Robert C. System and method for measuring particles in a sample stream of a flow cytometer using a low power laser source. United States: N. p., 2013.
Web.
Graves, Steven W, & Habbersett, Robert C. System and method for measuring particles in a sample stream of a flow cytometer using a low power laser source. United States.
Graves, Steven W, and Habbersett, Robert C. Tue .
"System and method for measuring particles in a sample stream of a flow cytometer using a low power laser source". United States. https://www.osti.gov/servlets/purl/1107599.
@article{osti_1107599,
title = {System and method for measuring particles in a sample stream of a flow cytometer using a low power laser source},
author = {Graves, Steven W and Habbersett, Robert C},
abstractNote = {A system and method for analyzing a particle in a sample stream of a flow cytometer or the like. The system has a light source, such as a laser pointer module, for generating a low powered light beam and a fluidics apparatus which is configured to transport particles in the sample stream at substantially low velocity through the light beam for interrogation. Detectors, such as photomultiplier tubes, are configured to detect optical signals generated in response to the light beam impinging the particles. Signal conditioning circuitry is connected to each of the detectors to condition each detector output into electronic signals for processing and is designed to have a limited frequency response to filter high frequency noise from the detector output signals.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2013},
month = {10}
}
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Works referenced in this record:
Development of a novel compact sonicator for cell disruption
journal, February 2005
- Borthwick, K. A. J.; Coakley, W. T.; McDonnell, M. B.
- Journal of Microbiological Methods, Vol. 60, Issue 2, p. 207-216
Method and apparatus for sorting particles with a moving catcher tube
patent, July 1991
- North, Jr., Howard L.
- US Patent Document 5,030,002
Apparatus and method employing incoherent light emitting semiconductor devices as particle detection light sources in a flow cytometer
patent, November 2004
- Hoffman, Robert A.; Chase, Eric
- US Patent Document 6,813,017
Ultrasonic particle-concentration for sheathless focusing of particles for analysis in a flow cytometer
journal, January 2006
- Goddard, Gregory; Martin, John C.; Graves, Steven W.
- Cytometry Part A, Vol. 69A, Issue 2, p. 66-74
Continuous cell washing and mixing driven by an ultrasound standing wave within a microfluidic channel
journal, January 2004
- Hawkes, Jeremy J.; Barber, Robert W.; Emerson, David R.
- Lab on a Chip, Vol. 4, Issue 5, p. 446-452
Theory of long wavelength acoustic radiation pressure
journal, October 1991
- Löfstedt, Ritva; Putterman, Seth
- The Journal of the Acoustical Society of America, Vol. 90, Issue 4, p. 2027-2033
Migration of suspended particles in plane stationary ultrasonic field
journal, January 1981
- Hiigashitani, Ko; Fukushima, Masahiro; Matsuno, Yoshizo
- Chemical Engineering Science, Vol. 36, Issue 12, p. 1877-1882
Increasing the luminescence of lanthanide complexes
journal, January 2006
- Leif, Robert C.; Vallarino, Lidia M.; Becker, Margie C.
- Cytometry Part A, Vol. 69A, Issue 8, p. 767-778
Using acoustic radiation force as a concentration method for erythrocytes
journal, July 1997
- Yasuda, Kenji; Haupt, Stephan Shuichi; Umemura, Shin-ichiro
- The Journal of the Acoustical Society of America, Vol. 102, Issue 1, p. 642-645
Optical detection system for flow cytometry
patent, April 2003
- Cabuz, Cleopatra; Zook, J. David; Cox, James Allen
- US Patent Document 6,549,275
Computational methods for the segmentation of images of objects from background in a flow imaging instrument
patent-application, May 2003
- Frost, Keith L.; Riley, James K.
- US Patent Application 10/200018; 20030086608
Particle Switching Systems and Methods Using Acoustic Radiation Pressure
patent-application, February 2009
- Ward, Michael D.; Stewart, Carleton C.; Kaduchak, Gregory
- US Patent Application 12/239410; 20090053686
Single particle high resolution spectral analysis flow cytometry
journal, January 2006
- Goddard, Gregory; Martin, John C.; Naivar, Mark
- Cytometry Part A, Vol. 69A, Issue 8, p. 842-851
System and method for measuring particles in a sample stream of a flow cytometer or the like
patent-application, May 2008
- Graves, Steven; Habbersett, Robert
- US Patent Application 11/593312; 20080106736
Scanning flow cytometry for individual particle analysis
journal, January 2000
- Maltsev, Valeri P.
- Review of Scientific Instruments, Vol. 71, Issue 1, p. 243-255
Optical detection system for flow cytometry
patent, August 2007
- Fritz, Bernard S.
- US Patent Document 7,262,838
Method and systems for dynamic range expansion
patent, April 2008
- Roth, Wayne D.
- US Patent Document 7,362,432
Cell–cell contact and membrane spreading in an ultrasound trap
journal, April 2004
- Coakley, W. T.; Bazou, D.; Morgan, J.
- Colloids and Surfaces B: Biointerfaces, Vol. 34, Issue 4, p. 221-230
Separation of dispersed phases from liquids in acoustically driven chambers
journal, February 1993
- Tolt, Thomas L.; Feke, Donald L.
- Chemical Engineering Science, Vol. 48, Issue 3, p. 527-540
Apparatus for using fluorescently labeled ligands in studying interaction of a native ligand and its receptor
patent, December 1994
- Yoshikami, Doju
- US Patent Document 5,376,551
Acoustic Radiation Pressure on a Rigid Sphere in a Viscous Fluid
journal, December 1994
- Doinikov, A. A.
- Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, Vol. 447, Issue 1931, p. 447-466
Measurement of Mammalian Erythrocyte Indices from Light Scattering with Scaning Flow Cytometer
conference, January 2003
- Semianov, K. A.; Tarasov, P. A.
- European Conference on Biomedical Optics, Diagnostic Optical Spectroscopy in Biomedicine II
Housing for a flow cytometry apparatus with particle unclogging feature
patent, December 1988
- North, Jr., Howard L.
- US Patent Document 4,790,653
Manipulating means utilizing ultrasonic wave energy for use with particulate material
patent, April 1991
- Schram, Cornelius J.
- US Patent Document 5,006,266
Manipulation of cells using an ultrasonic pressure field
journal, June 2005
- Haake, Albrecht; Neild, Adrian; Kim, Deok-Ho
- Ultrasound in Medicine & Biology, Vol. 31, Issue 6, p. 857-864
Data Analysis for a Dual-Channel Virus Counter
journal, April 2005
- Stoffel, Carrie L.; Rowlen, Kathy L.
- Analytical Chemistry, Vol. 77, Issue 7, p. 2243-2246
Apparatus for sterilizing a liquid with focused acoustic standing waves
patent, October 2008
- Zumeris, Jona; Levy, Jacob Y.; Hazan, Zadik
- US Patent Document 7,431,892
Device and Method for Noninvasive Ultrasonic Treatment of Fluids and Materials in Conduits and Cylindrical Containers
patent-application, February 2009
- Denslow, Kayte M.; Posakony, Gerald J.; Bond, Leonard J.
- US Patent Application 11/835854; 20090038932
Method and apparatus for separating particles by size
patent-application, April 2004
- Lal, Amit; Lee, Chung Hoon
- US Patent Application 10/263385; 20040065599
Near-Infrared Photo- and Electroluminescence of Alkoxy-Substituted Poly p-phenylene) and Nonconjugated Polymer/Lanthanide Tetraphenylporphyrin Blends
journal, July 2004
- Harrison, Benjamin S.; Foley, Timothy J.; Knefely, Alison S.
- Chemistry of Materials, Vol. 16, Issue 15, p. 2938-2947
Spatial light-scattering analysis as a means of characterizing and classifying non-spherical particles
journal, February 1998
- Kaye, Paul H.
- Measurement Science and Technology, Vol. 9, Issue 2, p. 141-149
Plasma preparation from whole blood using ultrasound
journal, June 2000
- Cousins, C. M.; Holownia, P.; Hawkes, J. J.
- Ultrasound in Medicine & Biology, Vol. 26, Issue 5, p. 881-888
Precise Measurements Of Particle Entrainment In A Standing-Wave Acoustic Field Between 20 And 3500 Hz
journal, December 2000
- González, Itzı́ar; Hoffmann, Thomas L.; Gallego, Juan A.
- Journal of Aerosol Science, Vol. 31, Issue 12, p. 1461-1468
The effect of centreline particle concentration in a wave tube
journal, January 1996
- Vainshtein, P.; Fichman, M.; Shuster, K.
- Journal of Fluid Mechanics, Vol. 306, p. 31-42
Quantum mechanical representation of acoustic streaming and acoustic radiation pressure
journal, July 2001
- Sato, Masanori; Fujii, Toshitaka
- Physical Review E, Vol. 64, Issue 2, Article No. 026311
Acoustic filtration and sedimentation of soot particles
journal, December 1997
- Martin, K. M.; Ezekoye, O. A.
- Experiments in Fluids, Vol. 23, Issue 6, p. 483-488
System and Method for Acoustic Focusing Hardware and Implementations
patent-application, July 2009
- Kaduchak, Gregory; Ward, Michael D.
- US Patent Application 12/209084; 20090178716
A new immobilisation method to arrange particles in a gel matrix by ultrasound standing waves
journal, February 2005
- Gherardini, Lisa; Cousins, Caroline M.; Hawkes, Jeremy J.
- Ultrasound in Medicine & Biology, Vol. 31, Issue 2, p. 261-272
Microparticle manipulation in millimetre scale ultrasonic standing wave chambers
journal, August 1998
- Hawkes, Jeremy J.; Barrow, David; Coakley, W. Terence
- Ultrasonics, Vol. 36, Issue 9, p. 925-931
Light-scattering properties of individual erythrocytes
journal, January 1999
- Shvalov, Alexandr N.; Soini, Juhani T.; Chernyshev, Andrey V.
- Applied Optics, Vol. 38, Issue 1, p. 230-235
Medium Switching Systems and Methods Using Acoustic Radiation Pressure
patent-application, February 2009
- Ward, Michael D.; Stewart, Carleton C.; Kaduchak, Gregory
- US Patent Application 12/239390; 20090050573
Modelling of particle paths passing through an ultrasonic standing wave
journal, April 2004
- Townsend, R. J.; Hill, M.; Harris, N. R.
- Ultrasonics, Vol. 42, Issue 1-9, p. 319-324
Microchip-Based Cell Lysis and DNA Extraction from Sperm Cells for Application to Forensic Analysis
journal, March 2006
- Bienvenue, Joan M.; Duncalf, Natalie; Marchiarullo, Daniel
- Journal of Forensic Sciences, Vol. 51, Issue 2, p. 266-273
Progress in Lanthanides as Luminescent Probes
journal, July 2005
- Hemmilä, I.; Laitala, V.
- Journal of Fluorescence, Vol. 15, Issue 4, p. 529-542
Enhanced synchronized ultrasonic and flow-field fractionation of suspensions
journal, March 1994
- Mandralis, Z.; Feke, D. L.; Bolek, W.
- Ultrasonics, Vol. 32, Issue 2, p. 113-122
Non-contact micromanipulation method and apparatus
patent, May 2000
- Kozuka, Teruyuki; Mitome, Hideto; Tuziuti, Toru
- US Patent Document 6,055,859
The use of ultrasonic standing waves to enhance optical particle sizing equipment
journal, March 2000
- Holwill, Ian L. J.
- Ultrasonics, Vol. 38, Issue 1-8, p. 650-653
Sub-micron particle manipulation in an ultrasonic standing wave: Applications in detection of clinically important biomolecules
journal, January 2000
- Sobanski, Michael A.; Robert Tucker, C.; Thomas, Nerys E.
- Bioseparation, Vol. 9, Issue 6, p. 351-357
Method and device for determining particle size distribution and zeta potential in concentrated dispersions
patent, September 2002
- Dukhin, Andrei; Goetz, Philip J.
- US Patent Document 6,449,563
Method for Non-Contact Particle Manipulation and Control of Particle Spacing Along on Axis
patent-application, April 2009
- Goddard, Gregory Russ; Kaduchak, Gregory; Jett, James Hubert
- US Patent Application 11/923403; 20090107241
Ultrasonic trapping of paramecia and estimation of their locomotive force
journal, October 1997
- Saito, Mitsunori; Izumida, Shin-ya; Hirota, Jun
- Applied Physics Letters, Vol. 71, Issue 14, p. 1909-1911
Linear and nonlinear frequency shifts in acoustical resonators with varying cross sections
journal, July 2001
- Hamilton, Mark F.; Ilinskii, Yurii A.; Zabolotskaya, Evgenia A.
- The Journal of the Acoustical Society of America, Vol. 110, Issue 1, p. 109-119
Phthalocyanine and tetrabenztriazaporphyrin reagents
patent, September 1994
- Renzoni, George E.; Schindele, Deborah C.; Theodore, Louis J.
- US Patent Document 5,346,670
Cellular platforms for HTS: three case studies
journal, March 2002
- Johnston, Paul A.; Johnston, Patricia A.
- Drug Discovery Today, Vol. 7, Issue 6, p. 353-363
Resolving leukocytes using axial light loss
journal, July 1989
- Stewart, Carleton C.; Stewart, Sigrid J.; Habbersett, Robert C.
- Cytometry, Vol. 10, Issue 4, p. 426-432
Particle analysis in an acoustic cytometer
patent-application, June 2009
- Kaduchak, Gregory; Ward, Michael D.
- US Patent Application 12/283491; 20090162887
Multifunctional Encoded Particles for High-Throughput Biomolecule Analysis
journal, March 2007
- Pregibon, Daniel C.; Toner, Mehmet; Doyle, Patrick S.
- Science, Vol. 315, Issue 5817, p. 1393-1396
Ultrasonic transducer and manufacturing method thereof
patent-application, April 2006
- Sawada, Yukihiko
- US Patent Application 11/242414; 20060071580
Transport and harvesting of suspended particles using modulated ultrasound
journal, November 1991
- Whitworth, G.; Grundy, M. A.; Coakley, W. T.
- Ultrasonics, Vol. 29, Issue 6, p. 439-444
Remote acoustic wave sensors
patent, May 1981
- Lim, Teong C.; Staples, Edward J.
- US Patent Document 4,265,124
Acoustic Concentration of Particles in Fluid Flow
patent-application, February 2011
- Ward, Michael D.; Kaduchak, Gregory
- US Patent Document 12/903042; 20110024335
A silicon microfluidic ultrasonic separator
journal, October 2003
- Harris, N. R.; Hill, M.; Beeby, S.
- Sensors and Actuators B: Chemical, Vol. 95, Issue 1-3, p. 425-434
Ultrasonic separations in analytical biotechnology
journal, December 1997
- Terence Coakley, W.
- Trends in Biotechnology, Vol. 15, Issue 12, p. 506-511
Concentration and Fractionation of Small Particles in Liquid by Ultrasound
journal, May 1995
- Yasuda, Kenji; Umemura, Shin-ichiro; Takeda, Kazuo
- Japanese Journal of Applied Physics, Vol. 34, Issue Part 1, No. 5B, p. 2715-2720
Method and apparatus for separating particles by size
patent, September 2006
- Lal, Amit; Lee, Chung Hoon
- US Patent Document 7,108,137
Lanthanide-based luminescence probes and time-resolved luminescence bioassays
journal, May 2006
- Yuan, Jingli; Wang, Guilan
- TrAC Trends in Analytical Chemistry, Vol. 25, Issue 5, p. 490-500
Ultrasonic flowmeter and manufacturing method thereof
patent, December 2003
- Ohkawa, Michio
- US Patent Document 6,668,664
Mean force on a small sphere in a sound field in a viscous fluid
journal, January 2000
- Danilov, S. D.; Mironov, M. A.
- The Journal of the Acoustical Society of America, Vol. 107, Issue 1, p. 143-153
Field-assisted extraction of cells, particles and macromolecules
journal, February 2002
- Karumanchi, Raghavarao S. M. S.; Doddamane, Srinivas N.; Sampangi, Chethana
- Trends in Biotechnology, Vol. 20, Issue 2, p. 72-78
Acoustically driven particle separation method and apparatus
patent, February 1992
- Feke, Donald L.; Tolt, Thomas L.
- US Patent Document 5,085,783
Actuators for microfluidics without moving parts
patent, May 2003
- Shenderov, Alexander
- US Patent Document 6,565,727
Flow cytometer for differentiating small particles in suspension
patent, September 2006
- Wells, Mark A.
- US Patent Document 7,113,266
Apparatus for moving particles from a first fluid to a second fluid
patent-application, July 2006
- Hawkes, Jeremy John; Coakley, William Terence
- US Patent Application 10/530131; 20060163166
Analytical scale ultrasonic standing wave manipulation of cells and microparticles
journal, March 2000
- Coakley, W. T.; Hawkes, J. J.; Sobanski, M. A.
- Ultrasonics, Vol. 38, Issue 1-8, p. 638-641
Ultrasound, a new separation technique to harvest microalgae
journal, March 2003
- Bosma, Rouke; van Spronsen, Wim A.; Tramper, Johannes
- Journal of Applied Phycology, Vol. 15, Issue 2-3, p. 143-153
High resolution imaging fountain flow cytometry
patent, January 2007
- Johnson, Paul E.
- US Patent Document 7,161,665
Imaging and analyzing parameters of small moving objects such as cells
patent, January 2008
- Ortyn, William E.; Basiji, David A.
- US Patent Document 7,315,357
Design of Electro-Mechanical Transducer Elements
patent, August 1959
- Palo, Maurice M.
- US Patent Document 2,900,536
Quantum Dot-Encoded Mesoporous Beads with High Brightness and Uniformity: Rapid Readout Using Flow Cytometry
journal, April 2004
- Gao, Xiaohu; Nie, Shuming
- Analytical Chemistry, Vol. 76, Issue 8, p. 2406-2410
A laminar flow expansion chamber facilitating downstream manipulation of particles concentrated using an ultrasonic standing wave
journal, July 1998
- Hawkes, Jeremy J.; Barrow, David; Cefai, Joseph
- Ultrasonics, Vol. 36, Issue 8, p. 901-903
Ultrasonic analyte concentration and application in flow cytometry
patent-application, January 2010
- Kaduchak, Gregory; Goddard, Greg; Salzman, Gary
- US Patent Application 11/982042; 20100000325
Electroacoustic production of murine hybridomas
journal, May 1990
- Bardsley, D. W.; Liddell, J. E.; Coakley, W. T.
- Journal of Immunological Methods, Vol. 129, Issue 1, p. 41-47
Liquid flow cytometer
patent, April 1998
- Gjelsnes, Oddbj. o. slashed. rn; Tangen, Reidar E.
- US Patent Document 5,739,902
Method of using actuators for microfluidics without moving parts
patent, August 2007
- Shenderov, Alexander
- US Patent Document 7,255,780
Microfluidic tools for biological sample preparation
conference, January 2002
- Visuri, S. R.; Ness, K.; Dzenitis, J.
- 2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology
Acoustic/Pressure Wave-Driven Separation Device
patent-application, March 2008
- Bagajewicz, Miguel
- US Patent Application 11/850439; 20080053787
Acoustic radiation force on a spherical particle in a viscous heat-conducting fluid. II. Force on a rigid sphere
journal, February 1997
- Doinikov, Alexander A.
- The Journal of the Acoustical Society of America, Vol. 101, Issue 2, p. 722-730
Angular distribution of light scattered by single biological cells and oriented particle agglomerates
journal, January 2003
- Neukammer, Jörg; Gohlke, Carsten; Höpe, Andreas
- Applied Optics, Vol. 42, Issue 31, p. 6388-6397
Acoustic control of suspended particles in micro fluidic chips
journal, January 2004
- Nilsson, Andreas; Petersson, Filip; Jönsson, Henrik
- Lab Chip, Vol. 4, Issue 2, p. 131-135
Acoustic radiation force on a spherical particle in a viscous heat-conducting fluid. I. General formula
journal, February 1997
- Doinikov, Alexander A.
- The Journal of the Acoustical Society of America, Vol. 101, Issue 2, p. 713-721
Dielectric particle focusing
patent-application, April 2005
- Gascoyne, Peter R.C.; Vykoukal, Jody V.
- US Patent Application 10/781057; 20050072677
Hydrodynamic orientation of cells.
journal, July 1977
- Fulwyler, M. J.
- Journal of Histochemistry & Cytochemistry, Vol. 25, Issue 7, p. 781-783
Broadband radial vibrator transducer with multiple resonant frequencies
patent, August 1986
- Thompson, Stephen C.
- US Patent Document 4,604,542
Particle analyzer with spatially split wavelength filter
patent, June 1996
- Hoffman, Robert A.; Treytl, William J.
- US Patent Document 5,528,045
Strategy for selection of methods for separation of bioparticles from particle mixtures
journal, January 2006
- van Hee, P.; Hoeben, M. A.; van der Lans, R. G. J. M.
- Biotechnology and Bioengineering, Vol. 94, Issue 4, p. 689-709
Ultrasonically cleaned membrane filtration system
patent, March 2006
- Weavers, Linda Kay; Walker, Harold W.; Lamminen, Mikko O.
- US Patent Document 7,008,540
Fluorescent dyes, energy transfer couples and methods
patent, August 2006
- O'Neill, Roger A.; Fisher, Peter Virgil
- US Patent Document 7,091,348
Methods for Acoustic Particle Focusing in Biological Sample Analyzers
patent-application, January 2010
- Auer, Robert E.
- US Patent Application 12/486207; 20100009333
Up-converting reporters for biological and other assays using laser excitation techniques
patent, October 1997
- Zarling, David A.; Rossi, Michel J.; Peppers, Norman A.
- US Patent Document 5,674,698
Compact efficient and robust ultraviolet solid-state laser sources based on nonlinear frequency conversion in periodically poled materials
patent, August 2009
- Essaian, Stepan; Shchegrov, Andrei V.
- US Patent Document 7,570,676
Modelling of layered resonators for ultrasonic separation
journal, May 2002
- Hill, Martyn; Shen, Yijun; Hawkes, Jeremy J.
- Ultrasonics, Vol. 40, Issue 1-8, p. 385-392
Multiplexed analysis of clinical specimens apparatus and methods
patent, November 1999
- Chandler, Van S.; Fulton, R. Jerrold; Chandler, Mark
- US Patent Document 5,981,180
Electron rich aromatics as cure promoters for radiation curable compositions
patent, June 1985
- Lee, George A.
- US Patent Document 4,523,982
E6 diffraction catastrophe of the primary rainbow of oblate water drops: observations with white-light and laser illumination
journal, January 1994
- Kaduchak, Gregory; Marston, Philip L.; Simpson, Harry J.
- Applied Optics, Vol. 33, Issue 21, p. 4691-4696
Methods and apparatus for moving and separating materials exhibiting different physical properties
patent, July 1988
- Peterson, Stephen C.; Brimhall, Owen D.; McLaughlin, Thomas J.
- US Patent Document 4,759,775
Acoustic concentration of particles in fluid flow
patent-application, October 2008
- Ward, Michael D.; Kaduchak, Gregory
- US Patent Application 11/784936; 20080245745
Device and method for separation
patent, August 2005
- Laurell, Thomas; Allers, Mats; Jönsson, Henrik
- US Patent Document 6,929,750
Imaging flow cytometer nearly simultaneously capturing a plurality of images
patent, July 1997
- Maekawa, Yasunori; Kosaka, Tokihiro
- US Patent Document 5,644,388
Measuring the velocity of small moving objects such as cells
patent, March 2003
- Ortyn, William E.; Basiji, David A.; Bauer, Richard A.
- US Patent Document 6,532,061
Method and apparatus for determination of the concentration of particles in multi-component fluid systems
patent-application, May 2007
- Priev, Aba; Ponomarev, Viktor Petrovich
- US Patent Application 11/289628; 20070119239
Improved quartz crystal microbalance technique
journal, August 1984
- Benes, E.
- Journal of Applied Physics, Vol. 56, Issue 3, p. 608-626
Micro particle trapping by opposite phases ultrasonic travelling waves
journal, July 1998
- Yamakoshi, Yoshiki; Noguchi, Yuji
- Ultrasonics, Vol. 36, Issue 8, p. 873-878
Hydrodynamic orientation of sperm heads for flow cytometry
journal, July 1978
- Dean, P. N.; Pinkel, D.; Mendelsohn, M. L.
- Biophysical Journal, Vol. 23, Issue 1, p. 7-13
Retention and Viability Characteristics of Mammalian Cells in an Acoustically Driven Polymer Mesh
journal, January 2004
- Wang, Zhaowei; Grabenstetter, Paul; Feke, Donald L.
- Biotechnology Progress, Vol. 20, Issue 1, p. 384-387
Identification of cell asymmetry and orientation by light scattering.
journal, July 1977
- Loken, M. R.; Parks, D. R.; Herzenberg, L. A.
- Journal of Histochemistry & Cytochemistry, Vol. 25, Issue 7, p. 790-795
Particle separation using ultrasound can be used with human shed mediastinal blood
journal, January 2005
- Jönsson, Henrik; Nilsson, Andreas; Petersson, Filip
- Perfusion, Vol. 20, Issue 1, p. 39-43
Effect of Process Parameters on Ultrasonic Separation of Dispersed Particles in Liquid
journal, May 1999
- Hatanaka, Shin-ichi; Taki, Tomohito; Kuwabara, Mamoru
- Japanese Journal of Applied Physics, Vol. 38, Issue Part 1, No. 5B, p. 3096-3100
Method for non-contact particle manipulation and control of particle spacing along an axis
patent-application, June 2009
- Goddard, Gregory Russ; Kaduchak, Gregory; Jett, James Hubert
- US Patent Application 12/288896; 20090139332
Hyperbolic umbilic and E6 diffraction catastrophes associated with the secondary rainbow of oblate water drops: observations with laser illumination
journal, January 1994
- Kaduchak, Gregory; Marston, Philip L.
- Applied Optics, Vol. 33, Issue 21, p. 4697-4701
Kits for Systems and Methods Using Acoustic Radiation Pressure
patent-application, February 2009
- Ward, Michael D.; Elling, John W.; Kaduchak, Gregory
- US Patent Application 12/239501; 20090045107
PDMS-based opto-fluidic micro flow cytometer with two-color, multi-angle fluorescence detection capability using PIN photodiodes
journal, March 2004
- Tung, Yi-Chung; Zhang, Min; Lin, Chih-Ting
- Sensors and Actuators B: Chemical, Vol. 98, Issue 2-3, p. 356-367
Fractionation of mixed particulate solids according to compressibility using ultrasonic standing wave fields
journal, October 1995
- Gupta, Sanjay; Feke, Donald L.; Manas-Zloczower, Ica
- Chemical Engineering Science, Vol. 50, Issue 20, p. 3275-3284
Method and apparatus for flow cytometry
patent, June 2001
- Malachowski, George C.
- US Patent Document 6,248,590
Tensile strength and visible ultrasonic cavitation of superfluid4He
journal, November 1976
- Marston, Philip L.
- Journal of Low Temperature Physics, Vol. 25, Issue 3-4, p. 383-407
Acoustic radiation force on a spherical particle in a viscous heat-conducting fluid. III. Force on a liquid drop
journal, February 1997
- Doinikov, Alexander A.
- The Journal of the Acoustical Society of America, Vol. 101, Issue 2, p. 731-740
Blood Concentration by Superposition of Higher Harmonics of Ultrasound
journal, May 1997
- Yasuda, Kenji
- Japanese Journal of Applied Physics, Vol. 36, Issue Part 1, No. 5B, p. 3130-3135
Acoustic filter for separating and recycling suspended particles
patent, May 1997
- Trampler, Felix; Piret, James M.; Sonderhoff, Stefan A.
- US Patent Document 5,626,767
Free Flow Acoustophoresis: Microfluidic-Based Mode of Particle and Cell Separation
journal, July 2007
- Petersson, Filip; Åberg, Lena; Swärd-Nilsson, Ann-Margret
- Analytical Chemistry, Vol. 79, Issue 14, p. 5117-5123
Material suspension within an acoustically excited resonant chamber
patent, May 1975
- Fletcher, James; Wang, Taylor; Saffren, Melvin
- US Patent Document 3,882,732
Single fiber model of particle retention in an acoustically driven porous mesh
journal, March 2003
- Grossner, Michael T.; Penrod, Alan E.; Belovich, Joanne M.
- Ultrasonics, Vol. 41, Issue 2, p. 65-74
Ultrasonic analyte concentration and application in flow cytometry
patent, March 2008
- Kaduchak, Gregory; Goddard, Greg; Salzman, Gary
- US Patent Document 7,340,957
Focus: Beads and chips: new recipes for analysis
journal, October 2003
- Verpoorte, Elisabeth
- Lab on a Chip, Vol. 3, Issue 4, p. 60N-68N
Controlled sample orientation and rotation in an acoustic levitator
patent, October 1988
- Barmatz, Martin B.; Gaspar, Mark S.; Trinh, Eugene H.
- US Patent Document 4,777,823
Method and apparatus for analyzing cells in a whole blood sample
patent, May 2001
- Rodriguez, Carlos M.; Cano, Jose M.; Carrillo, Barbara
- US Patent Document 6,228,652
Preparation of three terbium complexes with p-aminobenzoic acid and investigation of crystal structure influence on luminescence property
journal, October 2004
- Ye, Chao-Hong; Sun, Hao-Ling; Wang, Xin-Yi
- Journal of Solid State Chemistry, Vol. 177, Issue 10, p. 3735-3742
Ultrasonic concentration of carrier particles
patent-application, March 2007
- Dayton, Paul; Ferrara, Katherine W.; Zhao, Shukui
- US Patent Application 11/356843; 20070071683
Micro-organism manipulation and microparticle arrangement by the use of ultrasonic standing waves
conference, November 2001
- Saito, Mitsunori; Kitamura, Norio; Terauchi, Masaki
- International Symposium on Microelectronics and MEMS
Positioning, displacement, and localization of cells using ultrasonic forces
journal, January 2005
- Haake, Albrecht; Neild, Adrian; Radziwill, Gerald
- Biotechnology and Bioengineering, Vol. 92, Issue 1, p. 8-14
The Small-Angle Light Scattering of Biological Cells: Theoretical Considerations
journal, August 1970
- Mullaney, P. F.; Dean, P. N.
- Biophysical Journal, Vol. 10, Issue 8, p. 764-772
Methods for manipulating moieties in microfluidic systems
patent, July 2006
- Wang, Xiaobo; Wu, Lei; Cheng, Jing
- US Patent Document 7,081,192
Process for the separation of substances from a liquid and device for effecting such a process
patent, November 1992
- Stuckart, Wolfgang
- US Patent Document 5,164,094
Microparticle concentration in short path length ultrasonic resonators: Roles of radiation pressure and acoustic streaming
journal, October 2004
- Kuznetsova, Larisa A.; Coakley, W. Terence
- The Journal of the Acoustical Society of America, Vol. 116, Issue 4, p. 1956-1966
Diazo Coupling Method for Covalent Attachment of Proteins to Solid Substrates
journal, March 2006
- Wu, Yang; Buranda, Tione; Metzenberg, Robert L.
- Bioconjugate Chemistry, Vol. 17, Issue 2, p. 359-365
Laser machining of electroactive ceramics
patent-application, January 2006
- Masters, Brett P.; Rodgers, John P.; van Schoor, Marthinus C.
- US Patent Application 11/138803; 20060006769
A differential amplifier circuit for reducing noise in axial light loss measurements
journal, July 1983
- Steinkamp, John A.
- Cytometry, Vol. 4, Issue 1, p. 83-87
Positioning of small particles by an ultrasound field excited by surface waves
journal, April 2004
- Haake, A.; Dual, J.
- Ultrasonics, Vol. 42, Issue 1-9, p. 75-80
Side drift of aerosols in two-dimensional resonant acoustic levitators
journal, November 1997
- Dain, Y.
- The Journal of the Acoustical Society of America, Vol. 102, Issue 5, p. 2549-2555
Compact efficient and robust ultraviolet
patent-application, November 2007
- Essian, Stepan; Shchegrov, Andrei
- US Patent Application 11/788918; 20070263693
Laser diode-excited biological particle detection system
patent, December 2004
- Ho, Jim
- US Patent Document 6,831,279
Selective Retention of Viable Cells in Ultrasonic Resonance Field Devices
journal, February 1996
- Gaida, Th.; Doblhoff-Dier, O.; Strutzenberger, K.
- Biotechnology Progress, Vol. 12, Issue 1, p. 73-76
Cell discrimination by multiangle light scattering.
journal, January 1976
- Loken, M. R.; Sweet, R. G.; Herzenberg, L. A.
- Journal of Histochemistry & Cytochemistry, Vol. 24, Issue 1, p. 284-291
Contactless micromanipulation of small particles by an ultrasound field excited by a vibrating body
journal, May 2005
- Haake, Albrecht; Dual, Jurg
- The Journal of the Acoustical Society of America, Vol. 117, Issue 5, p. 2752-2760
Operating Characteristics of Acoustically Driven Filtration Processes for Particulate Suspensions
journal, January 2000
- Hill, Daniel H.; Feke, Donald L.
- Separation Science and Technology, Vol. 35, Issue 9, p. 1363-1375
Method of non-contact micromanipulation using ultrasound
patent, November 1998
- Kozuka, Teruyuki; Mitome, Hideto; Tuziuti, Toru
- US Patent Document 5,831,166
Antibody production from hybrid cell line
patent, September 1982
- Galfre, Giovanni; Milstein, Cesar; Wright, Bradford
- US Patent Document 4,350,683
Classification of Spectroscopically Encoded Resins by Raman Mapping and Infrared Hyperspectral Imaging
journal, March 2006
- Fenniri, Hicham; Terreau, Owen; Chun, Sangki
- Journal of Combinatorial Chemistry, Vol. 8, Issue 2, p. 192-198
A Novel Ultrasonic Resonance Field Device for the Retention of Animal Cells
journal, July 1994
- Doblhoff-Dier, O.; Gaida, Th.; Katinger, H.
- Biotechnology Progress, Vol. 10, Issue 4, p. 428-432
Enhanced sedimentation of mammalian cells following acoustic aggregation
journal, August 1989
- Kilburn, D. G.; Clarke, D. J.; Coakley, W. T.
- Biotechnology and Bioengineering, Vol. 34, Issue 4, p. 559-562
Aerodynamic beam generator for large particles
patent, February 2002
- Brockmann, John E.; Torczynski, John R.; Dykhuizen, Ronald C.
- US Patent Document 6,348,687
Dual-laser, differential fluorescence correction method for reducing cellular background autofluorescence
journal, November 1986
- Steinkamp, John A.; Stewart, Carleton C.
- Cytometry, Vol. 7, Issue 6, p. 566-574
Layered piezoelectric resonators with an arbitrary number of electrodes (general one‐dimensional treatment)
journal, September 1991
- Nowotny, Helmut; Benes, Ewald; Schmid, Michael
- The Journal of the Acoustical Society of America, Vol. 90, Issue 3, p. 1238-1245
Separation of sperm and vaginal cells with flow cytometry for DNA typing after sexual assault
journal, October 1999
- Schoell, Wolfgang M. J.; Klintschar, Michael; Mirhashemi, Ramin
- Obstetrics & Gynecology, Vol. 94, Issue 4, p. 623-627
Dynamics of suspended particles in a two-dimensional high-frequency sonic field
journal, June 1995
- Dain, Y.; Fichman, M.; Gutfinger, C.
- Journal of Aerosol Science, Vol. 26, Issue 4, p. 575-594
An analytical system based on a compact flow cytometer for DNA fragment sizing and single-molecule detection
journal, January 2004
- Habbersett, Robert C.; Jett, James H.
- Cytometry, Vol. 60A, Issue 2, p. 125-134
Method and apparatus for manipulation of cells and cell-like structures focused electric fields in microfludic systems and use thereof
patent, March 2006
- Orwar, Owe; Karlsson, Mattias; Chiu, Daniel T.
- US Patent Document 7,018,819
Standing‐wave acoustic trap for nonintrusive positioning of microparticles
journal, October 1995
- Hertz, H. M.
- Journal of Applied Physics, Vol. 78, Issue 8, p. 4845-4849
Acoustic separation in a laminar flow
conference, January 1994
- Brodeur, P. H.
- 1994 Proceedings of IEEE Ultrasonics Symposium
Generalized rainbows and unfolded glories of oblate drops: organization for multiple internal reflections and extension of cusps into Alexander's dark band
journal, January 1994
- Marston, Philip L.; Kaduchak, Gregory
- Applied Optics, Vol. 33, Issue 21, p. 4702-4713
Carrier Medium Exchange through Ultrasonic Particle Switching in Microfluidic Channels
journal, March 2005
- Petersson, Filip; Nilsson, Andreas; Jönsson, Henrik
- Analytical Chemistry, Vol. 77, Issue 5, p. 1216-1221
Particle agglutination immunoassay apparatus
patent, April 1990
- Imai, Kazumichi; Tokinaga, Daizo; Yokosawa, Koichi
- US Patent Document 4,913,883
Pulsed laser fluorescence spectrometer
journal, October 1987
- Aleksandrov, M. L.; Mel'tsin, A. L.; Lisitsyn, I. V.
- Journal of Applied Spectroscopy, Vol. 47, Issue 4, p. 1087-1092
Acousto-optic modulator for optical fibers using Hertzian contact with a grooved transducer substrate
patent, February 1991
- Kino, Gordon S.; Xiao, Guo Q.; Khuri-Yakub, Butrus T.
- US Patent Document 4,991,923
Acoustic streaming generated by standing waves in two-dimensional channels of arbitrary width
journal, January 2003
- Hamilton, Mark F.; Ilinskii, Yurii A.; Zabolotskaya, Evgenia A.
- The Journal of the Acoustical Society of America, Vol. 113, Issue 1, p. 153-160
Evaluation of SDF-1/CXCR4-induced Ca2+ signaling by fluorometric imaging plate reader (FLIPR) and flow cytometry
journal, December 2002
- Princen, Katrien; Hatse, Sigrid; Vermeire, Kurt
- Cytometry, Vol. 51A, Issue 1, p. 35-45
Upper sound pressure limits on particle concentration in fields of ultrasonic standing-wave at megahertz frequencies
journal, January 1992
- Gould, Robert K.; Coakley, W. Terence; Grundy, Martin A.
- Ultrasonics, Vol. 30, Issue 4, p. 239-244
High efficiency fluorescence flow cell for capillary liquid chromatography or capillary electrophoresis
patent, July 1995
- Sapp, Edwin; Weinberger, Robert Michael
- US Patent Document 5,430,541
Multilayered piezoelectric resonator for the separation of suspended particles
patent, January 1998
- Trampler, Felix; Benes, Ewald; Burger, Wolfgang
- US Patent Document 5,711,888
High throughput analysis of samples in flowing liquid
patent, October 2001
- Ambrose, W. Patrick; Grace, W. Kevin; Goodwin, Peter M.
- US Patent Document 6,309,886
Particle Quantifying Systems and Methods Using Acoustic Radiation Pressure
patent-application, February 2009
- Ward, Michael D.; Kaduchak, Gregory
- US Patent Application 12/239513; 20090042310
Acoustic concentration of particles in piezoelectric tubes: Theoretical modeling of the effect of cavity shape and symmetry breaking
journal, October 2004
- Kogan, Shulim; Kaduchak, Gregory; Sinha, Dipen N.
- The Journal of the Acoustical Society of America, Vol. 116, Issue 4, p. 1967-1974
Method of manufacturing a multi-layer semiconductor nanoparticle, and a multi-layer semiconductor nanoparticle manufactured by the method
patent, June 2005
- Sato, Keiichi; Kuwabata, Susumu
- US Patent Document 6,911,082
Coustic Concentration Method and Device and a Reaction Method
patent-application, September 2009
- Gauer, Christoph; Mann, Wolfgang
- US Patent Application 12/083792; 20090227042
On the drift of aerosol particles in sonic fields
journal, September 1992
- Vainshtein, P.; Fichman, M.; Pnueli, D.
- Journal of Aerosol Science, Vol. 23, Issue 6, p. 631-637
Dynamic Characterization of Particles with Flow Cytometry
patent-application, December 2009
- Matula, Thomas J.; Swalwell, Jarred
- US Patent Application 12/497281; 20090316151
Blue LED Excitable Temperature Sensors Based on a New Europium(III) Chelate
journal, February 2008
- Borisov, Sergey M.; Klimant, Ingo
- Journal of Fluorescence, Vol. 18, Issue 2, p. 581-589
Inorganic phosphors as new luminescent labels for immunocytochemistry and time-resolved microscopy
journal, January 1990
- Beverloo, H. B.; van Schadewijk, A.; van Gelderen-Boele, S.
- Cytometry, Vol. 11, Issue 7, p. 784-792
Laser diode-excited biological particle detection system
patent-application, May 2003
- Ho, Jim Yew-Wah
- US Patent Application 09/993488; 20030098421
On the Possibility of Long-Wavelength Long-Lifetime High-Quantum-Yield Luminophores
journal, January 2001
- Lakowicz, Joseph R.; Piszczek, Grzegorz; Kang, Jung Sook
- Analytical Biochemistry, Vol. 288, Issue 1, p. 62-75
Formation and growth of ice particles in stationary ultrasonic fields
journal, September 1998
- Bauerecker, Sigurd; Neidhart, Bernd
- The Journal of Chemical Physics, Vol. 109, Issue 10, p. 3709-3712
Particle manipulation
patent, December 2001
- Coakley, William Terence; Hawkes, Jeremy John; Barrow, David
- US Patent Document 6,332,541
The mean force acting on a small body in an axisymmetric sound field in a real medium
journal, January 1987
- Danilov, S. D.
- Fluid Dynamics, Vol. 21, Issue 5, p. 812-820
Coincidence in high-speed flow cytometry: Models and measurements
journal, January 1991
- Keij, Jan F.; Rotterdam, Ab Van; Groenewegen, Ad C.
- Cytometry, Vol. 12, Issue 5, p. 398-404
Method for using an all solid-state fluorometer in industrial water system applications
patent, July 2001
- Alfano, Joseph C.; Fehr, Michael; Godfrey, Martin R.
- US Patent Document 6,255,118
Consumable tube for use with a flow cytometry-based hematology system
patent, June 2006
- Roche, John W.; Hansen, W. Peter; Coleman, Michelle L.
- US Patent Document 7,064,823
Ultrasonic waves for fabricating lattice structure in composite materials
conference, September 1999
- Saito, Mitsunori; Itagaki, Kazuhiro; Imanishi, Yoshihiro
- SPIE's International Symposium on Optical Science, Engineering, and Instrumentation
Acoustic positioning and orientation prediction
patent, October 1990
- Barmatz, Martin B.; Aveni, Glenn; Putterman, Seth J.
- US Patent Document 4,964,303
Pulseless liquid supply system for flow cytometry
patent, June 1999
- North, Jr., Howard L.
- US Patent Document 5,915,925
Ultrasonic flow meter and ultrasonic sensor
patent-application, May 2005
- Ishikawa, Hiroaki; Shimizu, Kazuyoshi; Sekine, Ayumi
- US Patent Application 10/965158; 20050097968
Continuous separation of lipid particles from erythrocytes by means of laminar flow and acoustic standing wave forces
journal, January 2005
- Petersson, Filip; Nilsson, Andreas; Holm, Cecilia
- Lab on a Chip, Vol. 5, Issue 1, p. 20-22
Acoustically aided separation of oil droplets from aqueous emulsions
journal, August 2004
- Pangu, Gautam D.; Feke, Donald L.
- Chemical Engineering Science, Vol. 59, Issue 15, p. 3183-3193
Method for energy barrier equalization of magnetic recording media and media obtained thereby
patent, August 2004
- Brockie, Richard Michael; Richter, Hans J.
- US Patent Document 6,773,556
Ultrasonic Micromanipulator Using Visual Feedback
journal, May 1996
- Takeuchi, Masao; Abe, Hidetaka; Yamanouchi, Kazuhiko
- Japanese Journal of Applied Physics, Vol. 35, Issue Part 1, No. 5B, p. 3244-3247
Acoustic micromanipulation using a multi-electrode transducer
conference, January 1996
- Kozuka, T.; Tuziuti, T.; Mitome, H.
- MHS'96 Proceedings of the Seventh International Symposium on Micro Machine and Human Science
Single particle aerodynamic relaxation time analyzer
journal, June 1977
- Mazumder, M. K.; Kirsch, K. J.
- Review of Scientific Instruments, Vol. 48, Issue 6, p. 622-624
Separation of particles from a fluid by wave action
patent-application, February 2006
- Ferren, Bran; Hillis, W. Daniel; Sweeney, Elizabeth A.
- US Patent Application 10/919077; 20060034733
Batch and semicontinuous aggregation and sedimentation of hybridoma cells by acoustic resonance fields
journal, March 1995
- Pui, Phylis W. S.; Trampler, Felix; Sonderhoff, Stefan A.
- Biotechnology Progress, Vol. 11, Issue 2, p. 146-152
Method and apparatus for separating particulate from a flowing fluid
patent, November 1997
- Dickinson, Stuart C.; Kuklinski, Robert
- US Patent Document 5,688,406
Liquid/liquid fiber-optic fluorescence detector and absorbance analyzer
patent, September 1989
- Bach, David T.
- US Patent Document 4,867,559
Method and apparatus for acoustically driven media filtration
patent, April 2001
- Feke, Donald L.; Gupta, Sanjay; Mandralis, Zenon Ioannis
- US Patent Document 6,221,258
Methods, compositions, and automated systems for separating rare cells from fluid samples
patent, September 2005
- Yamanishi, Douglas; Hujsak, Paul; Yang, Zhaohuai
- US Patent Document 6,949,355
Design and characterization of a compact dual channel virus counter
journal, January 2005
- Stoffel, Carrie L.; Kathy, Robin Finch; Rowlen, Kathy L.
- Cytometry Part A, Vol. 65A, Issue 2, p. 140-147
Impedance spectroscopy flow cytometry: On-chip label-free cell differentiation
journal, January 2005
- Cheung, Karen; Gawad, Shady; Renaud, Philippe
- Cytometry Part A, Vol. 65A, Issue 2, p. 124-132
Ruthenium(II) complex with a notably long excited state lifetime
journal, January 2000
- Tyson, Daniel S.; Bialecki, Jason; Castellano, Felix N.
- Chemical Communications, Vol. 0, Issue 23, p. 2355-2356
On the Acoustic Radiation Pressure on Spheres
journal, November 1934
- King, L. V.
- Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, Vol. 147, Issue 861, p. 212-240
Continuous Flow Microfluidic Device for Rapid Erythrocyte Lysis
journal, November 2004
- Sethu, Palaniappan; Anahtar, Melis; Moldawer, Lyle L.
- Analytical Chemistry, Vol. 76, Issue 21, p. 6247-6253
Method and apparatus for performing phase fluorescence lifetime measurements in flow cytometry
patent, April 1996
- Lakowicz, Joseph R.; Berndt, Klaus W.; Hoffman, Robert A.
- US Patent Document 5,504,337
Particle handling apparatus for handling particles in fluid by acoustic radiation pressure
patent, April 2001
- Yasuda, Kenji; Umemura, Shin-ichiro; Kawabata, Kenichi
- US Patent Document 6,216,538
Cylindrical acoustic levitator/concentrator having non-circular cross-section
patent, November 2003
- Kaduchak, Gregory; Sinha, Dipen N.
- US Patent Document 6,644,118
Single half-wavelength ultrasonic particle filter: Predictions of the transfer matrix multilayer resonator model and experimental filtration results
journal, March 2002
- Hawkes, Jeremy J.; Coakley, W. Terence; Gröschl, Martin
- The Journal of the Acoustical Society of America, Vol. 111, Issue 3, p. 1259-1266
Ultrasonic four‐wave mixing mediated by an aqueous suspension of microspheres: Theoretical steady‐state properties
journal, September 1995
- Simpson, Harry J.; Marston, Philip L.
- The Journal of the Acoustical Society of America, Vol. 98, Issue 3, p. 1731-1741
Synthesis, Characterization, and Application of Eu(III), Tb(III), Sm(III), and Dy(III) Lanthanide Chelate Nanoparticle Labels
journal, April 2005
- Huhtinen, Petri; Kivelä, Mirja; Kuronen, Outi
- Analytical Chemistry, Vol. 77, Issue 8, p. 2643-2648
Screening method for red cell abnormality
patent, June 1986
- Hoffman, Robert A.; Kane, Richard; Price, Brandon J.
- US Patent Document 4,596,464
Extension of acoustic levitation to include the study of micron‐size particles in a more compressible host liquid
journal, May 1982
- Weiser, Mary Ann H.; Apfel, Robert E.
- The Journal of the Acoustical Society of America, Vol. 71, Issue 5, p. 1261-1268
Separation of a biocatalyst with ultrafiltration or filtration after bioconversion
journal, March 1997
- Meindersma, G. W.; Augeraud, J.; Vergossen, F. H. P.
- Journal of Membrane Science, Vol. 125, Issue 2, p. 333-349
Method and apparatus for detecting microparticles in fluid samples
patent, November 2004
- Goix, Philippe J.
- US Patent Document 6,816,257
Flow cytometry system with bubble detection
patent, July 2008
- Rich, Collin A.
- US Patent Document 7,403,125
Experimental and theoretical study of light scattering by individual mature red blood cells by use of scanning flow cytometry and a discrete dipole approximation
journal, January 2005
- Yurkin, Maxim A.; Semyanov, Konstantin A.; Tarasov, Peter A.
- Applied Optics, Vol. 44, Issue 25, p. 5249-5256
System for manipulating drops and bubbles using acoustic radiation pressure
patent, December 1999
- Oeftering, Richard C.
- US Patent Document 6,003,388
System for analyzing particles using multiple flow cytometry units
patent, July 2010
- Durack, Gary; Wallace, Jeffrey D.; Vandre, Gary P.
- US Patent Document 7,758,811
Acoustic Radiation Pressure of Plane Compressional Waves
journal, July 1953
- Borgnis, F. E.
- Reviews of Modern Physics, Vol. 25, Issue 3, p. 653-664
Control of a Standing Wave Field Using a Line-Focused Transducer for Two-Dimensional Manipulation of Particles
journal, May 1998
- Kozuka, Teruyuki; Tuziuti, Toru; Mitome, Hideto
- Japanese Journal of Applied Physics, Vol. 37, Issue Part 1, No. 5B, p. 2974-2978
Ultrasonic particle concentration in a line-driven cylindrical tube
journal, June 2005
- Goddard, Gregory; Kaduchak, Gregory
- The Journal of the Acoustical Society of America, Vol. 117, Issue 6, p. 3440-3447
A means for orienting flat cells in flow systems
journal, July 1978
- Stovel, R. T.; Sweet, R. G.; Herzenberg, L. A.
- Biophysical Journal, Vol. 23, Issue 1, p. 1-5
Optimization of high-sensitivity fluorescence detection
journal, September 1990
- Mathies, Richard A.; Peck, Konan.; Stryer, Lubert.
- Analytical Chemistry, Vol. 62, Issue 17, p. 1786-1791
Method and apparatus for separating particles
patent, July 1993
- Benes, Ewald; Hager, Ferdinand
- US Patent Document 5,225,089
Ultrasonic Micromanipulation of Small Particles in Liquid
journal, May 1994
- Takeuchi, Masao; Yamanouchi, Kazuhiko
- Japanese Journal of Applied Physics, Vol. 33, Issue Part 1, No. 5B, p. 3045-3047
Fluorescence background discrimination by prebleaching.
journal, January 1979
- Hirschfeld, T.
- Journal of Histochemistry & Cytochemistry, Vol. 27, Issue 1, p. 96-101
Chemiluminescence-based static and flow cytometry
patent, July 1991
- Bronstein, Irena; Voyta, John
- US Patent Document 5,032,381
Control of flow cytometer having vacuum fluidics
patent, March 1995
- North, Jr., Howard L.; Uffenheimer, Kenneth F.
- US Patent Document 5,395,588
Fractionation of cell mixtures using acoustic and laminar flow fields
journal, January 2004
- Kumar, Manoj; Feke, Donald L.; Belovich, Joanne M.
- Biotechnology and Bioengineering, Vol. 89, Issue 2, p. 129-137
Bioanalytical measuring method using oxidases and lanthanoid-ligand complexes
patent, May 2006
- Durkop, Axel; Wolfbeis, Otto S.
- US Patent Document 7,052,864
Deoxyribonucleic acid concentration using acoustic radiation force
journal, February 1996
- Yasuda, Kenji; Kiyama, Masaharu; Umemura, Shin‐ichiro
- The Journal of the Acoustical Society of America, Vol. 99, Issue 2, p. 1248-1251
Transport analysis and model for the performance of an ultrasonically enhanced filtration process
journal, June 2005
- Grossner, Michael T.; Belovich, Joanne M.; Feke, Donald L.
- Chemical Engineering Science, Vol. 60, Issue 12, p. 3233-3238
Apparatus and method for removing fine particles from a liquid medium by ultrasonic waves
patent, October 1977
- Porath-Furedi, Asher
- US Patent Document 4,055,491
Ultrasonic deposition of cells on a surface
journal, April 2004
- Hawkes, Jeremy J.; Long, Michael J.; Coakley, W.Terence
- Biosensors and Bioelectronics, Vol. 19, Issue 9, p. 1021-1028
The selection of layer thicknesses to control acoustic radiation force profiles in layered resonators
journal, January 2003
- Hill, Martyn
- The Journal of the Acoustical Society of America, Vol. 114, Issue 5, Article No. 2654
Continuous particle size separation and size sorting using ultrasound in a microchannel
journal, January 2006
- Kapishnikov, Sergey; Kantsler, Vasiliy; Steinberg, Victor
- Journal of Statistical Mechanics: Theory and Experiment, Vol. 2006, Issue 01, Article No. P01012
Analyzing system using sheath flow of sample
patent, January 1992
- Miyake, Ryo; Ohki, Hiroshi; Yamazaki, Isao
- US Patent Document 5,079,959
Method and system for examining the composition of a fluid or solid sample using fluorescence and/or absorption spectroscopy
patent, February 1996
- Kenny, Jonathan; Taylor, Todd
- US Patent Document 5,491,344
Separation and concentration of biological cells and biological particles using a one-dimensional channel
patent-application, February 2007
- Chiu, Daniel T.; Kuo, Jason S.
- US Patent Application 11/202416; 20070037172
Synthetic polymer particles for use as standards and calibrators in flow cytometry
patent, June 2000
- Zelmanovic, David; Moskalski, William; DeClercq, Ronny
- US Patent Document 6,074,879
Seven-Color Time-Resolved Fluorescence Hybridization Analysis of Human Papilloma Virus Types
journal, November 1997
- Samiotaki, Martina; Kwiatkowski, Marek; Ylitalo, Nathalie
- Analytical Biochemistry, Vol. 253, Issue 2, p. 156-161
Trapping of microparticles in the near field of an ultrasonic transducer
journal, March 2005
- Lilliehorn, Tobias; Simu, Urban; Nilsson, Mikael
- Ultrasonics, Vol. 43, Issue 5, p. 293-303
Use of acoustic radiation pressure to concentrate small particles in an air flow
conference, January 2002
- Anderson, M. J.; Budwig, R. S.; Line, K. S.
- 2002 IEEE Ultrasonics Symposium
Method and apparatus for the indentification of particles
patent, April 1992
- Bezanson, Donald S.
- US Patent Document 5,106,187
Dispersive near-IR Raman spectrometer
patent, April 2002
- Wise, Kent L.; Cooper, John B.; Schoen, Christian
- US Patent Document 6,373,567
Biological sample mixing apparatus and method
patent, July 1989
- Lary, Todd P.; Quintana, Jorge A.; Miranda, Osvaldo
- US Patent Document 4,845,025
Bioluminescence bathyphotometer
patent, November 1993
- Ferer, Kenneth M.; Case, James F.; Widder, Edith A.
- US Patent Document 5,264,906
Method and apparatus for acoustically driven media filtration
patent, September 2004
- Feke, Donald L.; Gupta, Sanjay; Mandralis, Zenon Ioannis
- US Patent Document 6,797,158
Method for enumerating blood cells
patent, March 2001
- Deka, Chiranjit; Wyatt, James L.; Gordon, Kristie M.
- US Patent Document 6,197,593
Methods for sampling a liquid flow
patent, February 2008
- Pamula, Vamsee K.; Pollack, Michael G.; Paik, Philip
- US Patent Document 7,329,545
Fluorescence proximity assay
patent-application, March 2003
- Evans, David Mark
- US Patent Application 10/256091; 20030059850
Focusing of microparticles in microfluidic systems
patent, July 2003
- Wada, H. Garrett; Kopf-Sill, Anne R.; Alajoki, Marja Liisa
- US Patent Document 6,592,821
Non-destructive, non-contact handling method for biomaterials in micro-chamber by ultrasound
journal, June 2000
- Yasuda, Kenji
- Sensors and Actuators B: Chemical, Vol. 64, Issue 1-3, p. 128-135
Major signal increase in fluorescence microscopy through dark-state relaxation
journal, December 2006
- Donnert, Gerald; Eggeling, Christian; Hell, Stefan W.
- Nature Methods, Vol. 4, Issue 1, p. 81-86
Manipulation of in vitro toxicant sensors in an ultrasonic standing wave
journal, February 2004
- Morgan, J.; Spengler, J. F.; Kuznetsova, L.
- Toxicology in Vitro, Vol. 18, Issue 1, p. 115-120
Physical enviroment of 2-D animal cell aggregates formed in a short pathlength ultrasound standing wave trap
journal, March 2005
- Bazou, Despina; Kuznetsova, Larisa A.; Coakley, W. Terence
- Ultrasound in Medicine & Biology, Vol. 31, Issue 3, p. 423-430
Method and apparatus for acoustically demixing aqueous solutions
patent, July 2000
- Raghavarao, Karumanchi Sreesaila Mallikarjuna Srinivasa; Todd, Paul W.
- US Patent Document 6,090,295
New types of microspheres and microsphere-related materials for medical diagnostics
journal, October 2002
- Slomkowski, Stanislaw; Basinska, Teresa; Miksa, Beata
- Polymers for Advanced Technologies, Vol. 13, Issue 10-12, p. 905-918
Experimental study of streaming flows associated with ultrasonic levitators
journal, November 1994
- Trinh, E. H.; Robey, J. L.
- Physics of Fluids, Vol. 6, Issue 11, p. 3567-3579
Method for discriminating between unstained and absorbing dye stained cells
patent, January 1985
- Hoffman, Robert A.; Ip, Stephen H.
- US Patent Document 4,492,752
Acoustic radiation potential on a sphere in plane, cylindrical, and spherical standing wave fields
journal, March 1985
- Barmatz, M.; Collas, P.
- The Journal of the Acoustical Society of America, Vol. 77, Issue 3, p. 928-945
Method for analysis of subpopulations of cells
patent, January 1991
- Brosnan, Jeanne; Ault, Kenneth
- US Patent Document 4,987,086
A numerically stable global matrix method for cylindrically layered shells excited by ring forces
journal, June 1994
- Ricks, David C.; Schmidt, Henrik
- The Journal of the Acoustical Society of America, Vol. 95, Issue 6, p. 3339-3349
Compact acoustic levitation device for studies in fluid dynamics and material science in the laboratory and microgravity
journal, November 1985
- Trinh, E. H.
- Review of Scientific Instruments, Vol. 56, Issue 11, p. 2059-2065
A micro-particle positioning technique combining an ultrasonic manipulator and a microgripper
journal, June 2006
- Neild, Adrian; Oberti, Stefano; Beyeler, Felix
- Journal of Micromechanics and Microengineering, Vol. 16, Issue 8, p. 1562-1570
Ultrasonic manipulation of locomotive microorganisms and evaluation of their activity
journal, December 2002
- Saito, Mitsunori; Kitamura, Norio; Terauchi, Masaki
- Journal of Applied Physics, Vol. 92, Issue 12, p. 7581-7586
A computer-controlled system for the measurement of complete admittance spectra of piezoelectric resonators
journal, September 1990
- Schmid, M.; Benes, E.; Sedlaczek, R.
- Measurement Science and Technology, Vol. 1, Issue 9, p. 970-975
Sheathed particle flow controlled by differential pressure
patent, August 1991
- North, Jr., Howard L.
- US Patent Document 5,040,890
High solid infrared absorbing compositions
patent, September 1998
- Chiang, Chwan-Hwa; Dawson, William R.; Kinney, Layton F.
- US Patent Document 5,800,861
Single-collector experiments and modeling of acoustically aided mesh filtration
journal, January 2005
- Grossner, Michael T.; Feke, Donald L.; Belovich, Joanne M.
- AIChE Journal, Vol. 51, Issue 6, p. 1590-1598
Apparatus for directing particles in a fluid
patent, May 2008
- Hawkes, Jeremy John; Long, Michael; Coakley, William Terence
- US Patent Document 7,373,805
Device and method for separation
patent-application, April 2004
- Laurell, Thomas; Allers, Mats; Jonsson, Henrik
- US Patent Application 10/467843; 20040069717
Resonator frequency shift due to ultrasonically induced microparticle migration in an aqueous suspension: Observations and model for the maximum frequency shift
journal, June 1998
- Kwiatkowski, Christopher S.; Marston, Philip L.
- The Journal of the Acoustical Society of America, Vol. 103, Issue 6, p. 3290-3300
Particle separation using acoustic radiation force and elecrostatic force
journal, April 1996
- Yasuda, Kenji; Umemura, Shin‐ichiro; Takeda, Kazuo
- The Journal of the Acoustical Society of America, Vol. 99, Issue 4, p. 1965-1970
Multi-analyte diagnostic system and computer implemented process for same
patent-application, December 2003
- Chandler, Van S.
- US Patent Application 10/442130; 20030235919
Manipulating particulate matter
patent, October 1989
- Schram, Cornelius J.
- US Patent Document 4,877,516
Particle Fusing Systems and Methods Using Acoustic Radiation Pressure
patent-application, February 2009
- Ward, Michael D.; Kaduchak, Gregory
- US Patent Application 12/239483; 20090042239
Method and apparatus for the generation of ultrasonic energy fields within circular structures containing a liquid
patent, May 2004
- Poniatowski, John; Poniatowski, Susan E.; Walkinshaw, John W.
- US Patent Document 6,736,904
High sensitivity fluorescent single particle and single molecule detection apparatus and method
patent, December 1990
- Mathies, Richard A.; Peck, Konan; Stryer, Lubert
- US Patent Document 4,979,824
SPART analyzer: its application to aerodynamic size distribution measurement
journal, January 1979
- Mazumder, M. K.; Ware, R. E.; Wilson, J. D.
- Journal of Aerosol Science, Vol. 10, Issue 6, p. 561-569
Modelling in the design of a flow-through ultrasonic separator
journal, March 2000
- Hill, Martyn; Wood, Robert J. K.
- Ultrasonics, Vol. 38, Issue 1-8, p. 662-665
Manipulation of Fluid Objects with Acoustic Radiation Pressure
journal, January 2006
- Marston, Philip L.; Thiessen, David B.
- Annals of the New York Academy of Sciences, Vol. 1027, Issue 1, p. 414-434
Sensors and methods for high-sensitivity optical particle counting and sizing
patent, September 2004
- Nicoli, David F.; Toumbas, Paul
- US Patent Document 6,794,671
Apparatus for separating particles utilizing engineered acoustic contrast capture particles
patent-application, October 2008
- Kaduchak, Gregory; Ward, Michael D.
- US Patent Application 11/784928; 20080245709
Apparatus for monitoring substances in organisms
patent, August 1998
- Goix, Philippe J.
- US Patent Document 5,798,222
Particle column formation in a stationary ultrasonic field
journal, January 1992
- Whitworth, Glenn; Coakley, W. T.
- The Journal of the Acoustical Society of America, Vol. 91, Issue 1, p. 79-85
Ultrasonic analyte concentration and application in flow cytometry
patent-application, February 2006
- Kaduchak, Gregory; Goddard, Greg; Salzman, Gary
- US Patent Application 10/979065; 20060021437
Particle Characterization and Separation by a Coupled Acoustic−Gravity Field
journal, July 2001
- Masudo, Takashi; Okada, Tetsuo
- Analytical Chemistry, Vol. 73, Issue 14, p. 3467-3471
Acoustic agglomeration of a glycol fog aerosol: Influence of particle concentration and intensity of the sound field at two frequencies
journal, June 1995
- Capéran, Ph.; Somers, J.; Richter, K.
- Journal of Aerosol Science, Vol. 26, Issue 4, p. 595-612
Method and apparatus for field flow fractionation
patent, August 1981
- Kirkland, Joseph J.; Yau, Wallace W.
- US Patent Document 4,285,810
Cylindrical acoustic levitator/concentrator
patent, October 2002
- Kaduchak, Gregory; Sinha, Dipen N.
- US Patent Document 6,467,350
Ultrasonic monitor of material composition and particle size
patent, May 2006
- Cobb, Wesley N.
- US Patent Document 7,047,809
Ultrasonic separation in microfluidic capillaries
conference, January 2003
- Araz, M. K.; Lee, Chung-Hoon; Lal, A.
- IEEE Symposium on Ultrasonics, 2003
Virus removal in a membrane separation process
journal, May 1998
- Otaki, Masahiro; Yano, Kazuyoshi; Ohgaki, Shinichiro
- Water Science and Technology, Vol. 37, Issue 10
Low acceleration method of flow cytometry
patent, August 2003
- Buchanan, Kris; Herickhoff, Lisa A.
- US Patent Document 6,604,435
Apparatuses and methods for field flow fractionation of particles using acoustic and other forces
patent, April 2005
- Wang, Xiao-Bo; Cheng, Jing; Wu, Lei
- US Patent Document 6,881,314
Mathematical modeling of the movement of suspended particles subjected to acoustic and flow fields
journal, June 2005
- Aboobaker, N.; Blackmore, D.; Meegoda, J.
- Applied Mathematical Modelling, Vol. 29, Issue 6, p. 515-532
Particle Analyzing Systems and Methods Using Acoustic Radiation Pressure
patent-application, January 2009
- Ward, Michael D.; Kaduchak, Gregory
- US Patent Application 12/239453; 20090029870
High throughput particle analysis: Combining dielectrophoretic particle focussing with confocal optical detection
journal, February 2006
- Holmes, David; Morgan, Hywel; Green, Nicolas G.
- Biosensors and Bioelectronics, Vol. 21, Issue 8, p. 1621-1630
Acoustic particle separation
patent, June 1985
- Barmatz, Martin B.; Stoneburner, James D.; Jacobi, Nathan
- US Patent Document 4,523,682
Apparatus and method for volumetric capillary cytometry
patent, August 1996
- Baer, Thomas M.; Dietz, Louis J.; Dubrow, Robert S.
- US Patent Document 5,547,849
Apparatuses, Systems, Methods, And Computer Readable Media For Acoustic Flow Cytometry.
patent-application, June 2011
- Kaduchak, Gregory; Ward, Michael; Bradford, Jolene
- US Patent Application 12/955282; 20110134426
Cavitation bubble-driven cell and particle behavior in an ultrasound standing wave
journal, January 2005
- Kuznetsova, Larisa A.; Khanna, Sanjay; Amso, Nazar N.
- The Journal of the Acoustical Society of America, Vol. 117, Issue 1, p. 104-112
Time-resolved flow cytometry for the measurement of lanthanide chelate fluorescence: I. Concept and theoretical evaluation
journal, July 1994
- Condrau, Marc A.; Schwendener, Reto A.; Niederer, Peter
- Cytometry, Vol. 16, Issue 3, p. 187-194
Trapping of heavy gases in stationary ultrasonic fields
journal, September 2002
- Tuckermann, Rudolf; Neidhart, Bernd; Lierke, Ernst G.
- Chemical Physics Letters, Vol. 363, Issue 3-4, p. 349-354
Human nonsecretory plasmacytoid cell line
patent, February 1984
- Ritts, Jr., Roy E.
- US Patent Document 4,434,230
Time-resolved flow cytometry for the measurement of lanthanide chelate fluorescence: II. Instrument design and experimental results
journal, July 1994
- Condrau, Marc A.; Schwendener, Reto A.; Zimmermann, Marcel
- Cytometry, Vol. 16, Issue 3, p. 195-205
Separation devices based on forced coincidence response of fluid‐filled pipes
journal, June 1992
- Tolt, Thomas L.; Feke, Donald L.
- The Journal of the Acoustical Society of America, Vol. 91, Issue 6, p. 3152-3156
Acoustic Positioning for Space Processing of Materials Science Samples in Mirror Furnaces
conference, January 1983
- Lierke, E. G.; Grossbach, R.; Flogel, K.
- 1983 Ultrasonics Symposium
Multilayered piezoelectric resonator for the separation of suspended particles
patent, June 1996
- Trampler, Felix; Benes, Ewald; Burger, Wolfgang
- US Patent Document 5,527,460
Fluorescence detection instrument with reflective transfer legs for color decimation
patent, January 2004
- Oostman, Jr., Clifford A.; Blasenheim, Barry
- US Patent Document 6,683,314
Design, modeling and characterization of microfluidic devices for ultrasonic manipulation
journal, February 2007
- Neild, Adrian; Oberti, Stefano; Dual, Jürg
- Sensors and Actuators B: Chemical, Vol. 121, Issue 2, p. 452-461
Acoustically driven collection of suspended particles within porous media
journal, March 1997
- Gupta, Sanjay; Feke, Donald L.
- Ultrasonics, Vol. 35, Issue 2, p. 131-139
Using Optical Scattering to Measure Properties of Ultrasound Contrast Agent Shells
patent-application, May 2007
- Matula, Thomas; Guan, Jingfeng
- US Patent Application 11/531998; 20070098232
Particle Imaging Systems and Methods Using Acoustic Radiation Pressure
patent-application, February 2009
- Kaduchak, Gregory; Stewart, Carleton C.; Ward, Michael D.
- US Patent Application 12/239467; 20090048805
Force field particle filter, combining ultrasound standing waves and laminar flow
journal, May 2001
- Hawkes, Jeremy J.; Coakley, W. Terence
- Sensors and Actuators B: Chemical, Vol. 75, Issue 3, p. 213-222
Particle analysis in an acoustic cytometer
patent-application, June 2009
- Kaduchak, Gregory; Ward, Michael D.
- US Patent Application 12/283461; 20090158823
Flow cell apparatus
patent, November 1997
- Matsumoto, Mariko; Yamazaki, Isao; Miyake, Ryo
- US Patent Document 5,690,895