Visual-servoing optical microscopy
Abstract
The present invention provides methods and devices for the knowledge-based discovery and optimization of differences between cell types. In particular, the present invention provides visual servoing optical microscopy, as well as analysis methods. The present invention provides means for the close monitoring of hundreds of individual, living cells over time; quantification of dynamic physiological responses in multiple channels; real-time digital image segmentation and analysis; intelligent, repetitive computer-applied cell stress and cell stimulation; and the ability to return to the same field of cells for long-term studies and observation. The present invention further provides means to optimize culture conditions for specific subpopulations of cells.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1107355
- Patent Number(s):
- 8548745
- Application Number:
- 13/107,601
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
G - PHYSICS G06 - COMPUTING G06K - RECOGNITION OF DATA
C - CHEMISTRY C12 - BIOCHEMISTRY C12M - APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
- DOE Contract Number:
- AC03-76SF00098
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Callahan, Daniel E, and Parvin, Bahram. Visual-servoing optical microscopy. United States: N. p., 2013.
Web.
Callahan, Daniel E, & Parvin, Bahram. Visual-servoing optical microscopy. United States.
Callahan, Daniel E, and Parvin, Bahram. Tue .
"Visual-servoing optical microscopy". United States. https://www.osti.gov/servlets/purl/1107355.
@article{osti_1107355,
title = {Visual-servoing optical microscopy},
author = {Callahan, Daniel E and Parvin, Bahram},
abstractNote = {The present invention provides methods and devices for the knowledge-based discovery and optimization of differences between cell types. In particular, the present invention provides visual servoing optical microscopy, as well as analysis methods. The present invention provides means for the close monitoring of hundreds of individual, living cells over time; quantification of dynamic physiological responses in multiple channels; real-time digital image segmentation and analysis; intelligent, repetitive computer-applied cell stress and cell stimulation; and the ability to return to the same field of cells for long-term studies and observation. The present invention further provides means to optimize culture conditions for specific subpopulations of cells.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2013},
month = {10}
}
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Works referenced in this record:
Miniaturized FRET assays and microfluidics: key components for ultra-high-throughput screening
journal, August 1999
- Mere, L.
- Drug Discovery Today, Vol. 4, Issue 8
Intracellular calcium dependence of gene expression in single T lymphocytes.
journal, March 1994
- Negulescu, P. A.; Shastri, N.; Cahalan, M. D.
- Proceedings of the National Academy of Sciences, Vol. 91, Issue 7
Swelling-activated chloride channels in multidrug-sensitive and -resistant cells.
journal, December 1994
- Ehring, G. R.; Osipchuk, Y. V.; Cahalan, M. D.
- Journal of General Physiology, Vol. 104, Issue 6
Visual servoing for online facilities
journal, July 1997
- Parvin, B.; Taylor, J. R.; Callahan, D. E.
- Computer, Vol. 30, Issue 7
Microcomputer-controlled device for delivering hormone stimulation to cell suspensions in perifusion: release of luteinising hormone from sheep pituitary cells
journal, May 1984
- McIntosh, J. E. A.; McIntosh, R. P.; Kean, R. J.
- Medical & Biological Engineering & Computing, Vol. 22, Issue 3
Leginon: a system for fully automated acquisition of 1000 electron micrographs a day
journal, July 1999
- Potter, C. S.; Chu, H.; Frey, B.
- Ultramicroscopy, Vol. 77, Issue 3-4
A Collaborative Framework for Distributed Microscopy
conference, January 1998
- Parvin, B.; Taylor, J.; Cong, G.
- SC98 - High Performance Networking and Computing Conference, Proceedings of the IEEE/ACM SC98 Conference
Mitogen-induced oscillations of cytosolic Ca2+ and transmembrane Ca2+ current in human leukemic T cells.
journal, November 1989
- Lewis, R. S.; Cahalan, M. D.
- Cell Regulation, Vol. 1, Issue 1