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Title: System and method for collisional activation of charged particles

Abstract

A collision cell is disclosed that provides ion activation in various selective modes. Ion activation is performed inside selected segments of a segmented quadrupole that provides maximum optimum capture and collection of fragmentation products. The invention provides collisional cooling of precursor ions as well as product fragments and further allows effective transmission of ions through a high pressure interface into a coupled mass analysis instrument.

Inventors:
; ;
Issue Date:
Research Org.:
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1096008
Patent Number(s):
8541737
Application Number:
12/769,268
Assignee:
Battelle Memorial Institute (Richland, WA)
Patent Classifications (CPCs):
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
DOE Contract Number:  
AC06-76RL01830
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Citation Formats

Ibrahim, Yehia M, Belov, Mikhail E, and Prior, David C. System and method for collisional activation of charged particles. United States: N. p., 2013. Web.
Ibrahim, Yehia M, Belov, Mikhail E, & Prior, David C. System and method for collisional activation of charged particles. United States.
Ibrahim, Yehia M, Belov, Mikhail E, and Prior, David C. Tue . "System and method for collisional activation of charged particles". United States. https://www.osti.gov/servlets/purl/1096008.
@article{osti_1096008,
title = {System and method for collisional activation of charged particles},
author = {Ibrahim, Yehia M and Belov, Mikhail E and Prior, David C},
abstractNote = {A collision cell is disclosed that provides ion activation in various selective modes. Ion activation is performed inside selected segments of a segmented quadrupole that provides maximum optimum capture and collection of fragmentation products. The invention provides collisional cooling of precursor ions as well as product fragments and further allows effective transmission of ions through a high pressure interface into a coupled mass analysis instrument.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Sep 24 00:00:00 EDT 2013},
month = {Tue Sep 24 00:00:00 EDT 2013}
}

Works referenced in this record:

Ion Mobility-Mass Spectrometer Interface for Collisional Activation of Mobility Separated Ions
journal, January 2009


High efficiency collision-induced dissociation in an RF-only quadrupole
journal, June 1979


The high-pressure segmented quadrupole collision cell (HP-SQCC) as an ion molecule reactor
journal, June 2005


A novel approach to collision-induced dissociation (CID) for ion mobility-mass spectrometry experiments
journal, June 2009


Segmented vane radio-frequency quadrupole linear accelerator
patent, July 1995


Improved Collisionally Activated Dissociation Efficiency and Mass Resolution on a Triple Quadrupole Mass Spectrometer System
journal, May 1995