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Title: Facilitating protein solubility by use of peptide extensions

Abstract

Expression vectors for expression of a protein or polypeptide of interest as a fusion product composed of the protein or polypeptide of interest fused at one terminus to a solubility enhancing peptide extension are provided. Sequences encoding the peptide extensions are provided. The invention further comprises antibodies which bind specifically to one or more of the solubility enhancing peptide extensions.

Inventors:
; ;
Issue Date:
Research Org.:
BNL (Brookhaven National Laboratory (BNL), Upton, NY (United States))
Sponsoring Org.:
USDOE
OSTI Identifier:
1093445
Patent Number(s):
8,535,908
Application Number:
12/684,195
Assignee:
Brookhaven Science Associates, LLC (Upton, NY)
DOE Contract Number:  
AC02-98CH10886
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Freimuth, Paul I, Zhang, Yian-Biao, and Howitt, Jason. Facilitating protein solubility by use of peptide extensions. United States: N. p., 2013. Web.
Freimuth, Paul I, Zhang, Yian-Biao, & Howitt, Jason. Facilitating protein solubility by use of peptide extensions. United States.
Freimuth, Paul I, Zhang, Yian-Biao, and Howitt, Jason. Tue . "Facilitating protein solubility by use of peptide extensions". United States. https://www.osti.gov/servlets/purl/1093445.
@article{osti_1093445,
title = {Facilitating protein solubility by use of peptide extensions},
author = {Freimuth, Paul I and Zhang, Yian-Biao and Howitt, Jason},
abstractNote = {Expression vectors for expression of a protein or polypeptide of interest as a fusion product composed of the protein or polypeptide of interest fused at one terminus to a solubility enhancing peptide extension are provided. Sequences encoding the peptide extensions are provided. The invention further comprises antibodies which bind specifically to one or more of the solubility enhancing peptide extensions.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2013},
month = {9}
}

Patent:

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