skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Methods for attaching polymerizable ceragenins to water treatment membranes using silane linkages

Abstract

This invention relates to methods for chemically grafting and attaching ceragenin molecules to polymer substrates; methods for synthesizing ceragenin-containing copolymers; methods for making ceragenin-modified water treatment membranes and spacers; and methods of treating contaminated water using ceragenin-modified treatment membranes and spacers. Ceragenins are synthetically produced antimicrobial peptide mimics that display broad-spectrum bactericidal activity. Alkene-functionalized ceragenins (e.g., acrylamide-functionalized ceragenins) can be attached to polyamide reverse osmosis membranes using amine-linking, amide-linking, UV-grafting, or silane-coating methods. In addition, silane-functionalized ceragenins can be directly attached to polymer surfaces that have free hydroxyls.

Inventors:
; ; ;
Issue Date:
Research Org.:
SNL-A (Sandia National Laboratories, Albuquerque, NM (United States))
Sponsoring Org.:
USDOE
OSTI Identifier:
1092937
Patent Number(s):
8,530,002
Application Number:
12/986,221
Assignee:
Sandia Corporation (Albuquerque, NM) SNL-A
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Hibbs, Michael, Altman, Susan J., Jones, Howland D. T., and Savage, Paul B. Methods for attaching polymerizable ceragenins to water treatment membranes using silane linkages. United States: N. p., 2013. Web.
Hibbs, Michael, Altman, Susan J., Jones, Howland D. T., & Savage, Paul B. Methods for attaching polymerizable ceragenins to water treatment membranes using silane linkages. United States.
Hibbs, Michael, Altman, Susan J., Jones, Howland D. T., and Savage, Paul B. Tue . "Methods for attaching polymerizable ceragenins to water treatment membranes using silane linkages". United States. https://www.osti.gov/servlets/purl/1092937.
@article{osti_1092937,
title = {Methods for attaching polymerizable ceragenins to water treatment membranes using silane linkages},
author = {Hibbs, Michael and Altman, Susan J. and Jones, Howland D. T. and Savage, Paul B.},
abstractNote = {This invention relates to methods for chemically grafting and attaching ceragenin molecules to polymer substrates; methods for synthesizing ceragenin-containing copolymers; methods for making ceragenin-modified water treatment membranes and spacers; and methods of treating contaminated water using ceragenin-modified treatment membranes and spacers. Ceragenins are synthetically produced antimicrobial peptide mimics that display broad-spectrum bactericidal activity. Alkene-functionalized ceragenins (e.g., acrylamide-functionalized ceragenins) can be attached to polyamide reverse osmosis membranes using amine-linking, amide-linking, UV-grafting, or silane-coating methods. In addition, silane-functionalized ceragenins can be directly attached to polymer surfaces that have free hydroxyls.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2013},
month = {9}
}

Patent:

Save / Share: