SE-72/AS-72 generator system based on Se extraction/ As reextraction
Abstract
The preparation of a .sup.72Se/.sup.72As radioisotope generator involves forming an acidic aqueous solution of an irradiated alkali bromide target such as a NaBr target, oxidizing soluble bromide in the solution to elemental bromine, removing the elemental bromine, evaporating the resulting solution to a residue, removing hydrogen chloride from the residue, forming an acidic aqueous solution of the residue, adding a chelator that selectively forms a chelation complex with selenium, and extracting the chelation complex from the acidic aqueous solution into an organic phase. As the .sup.72Se generates .sup.72As in the organic phase, the .sup.72As may be extracted repeatedly from the organic phase with an aqueous acid solution.
- Inventors:
- Issue Date:
- Research Org.:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1092935
- Patent Number(s):
- 8529873
- Application Number:
- 13/216,964
- Assignee:
- Los Alamos National Security, LLC (Los Alamos, NM)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- DOE Contract Number:
- AC52-06NA25396
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Fassbender, Michael Ernst, and Ballard, Beau D. SE-72/AS-72 generator system based on Se extraction/ As reextraction. United States: N. p., 2013.
Web.
Fassbender, Michael Ernst, & Ballard, Beau D. SE-72/AS-72 generator system based on Se extraction/ As reextraction. United States.
Fassbender, Michael Ernst, and Ballard, Beau D. Tue .
"SE-72/AS-72 generator system based on Se extraction/ As reextraction". United States. https://www.osti.gov/servlets/purl/1092935.
@article{osti_1092935,
title = {SE-72/AS-72 generator system based on Se extraction/ As reextraction},
author = {Fassbender, Michael Ernst and Ballard, Beau D},
abstractNote = {The preparation of a .sup.72Se/.sup.72As radioisotope generator involves forming an acidic aqueous solution of an irradiated alkali bromide target such as a NaBr target, oxidizing soluble bromide in the solution to elemental bromine, removing the elemental bromine, evaporating the resulting solution to a residue, removing hydrogen chloride from the residue, forming an acidic aqueous solution of the residue, adding a chelator that selectively forms a chelation complex with selenium, and extracting the chelation complex from the acidic aqueous solution into an organic phase. As the .sup.72Se generates .sup.72As in the organic phase, the .sup.72As may be extracted repeatedly from the organic phase with an aqueous acid solution.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2013},
month = {9}
}
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
An isotope generator for 72As
journal, November 1978
- Al-Kouraishi, S. H.; Boswell, G. G. J.
- The International Journal of Applied Radiation and Isotopes, Vol. 29, Issue 11
Proton beam simulation with MCNPX: Gallium metal activation estimates below 30MeV relevant to the bulk production of 68Ge and 65Zn
journal, August 2007
- Fassbender, M.; Arzumanov, A.; Jamriska, D. J.
- Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 261, Issue 1-2
Speciation of selenium(IV) and selenium(VI) in environmental samples by the combination of graphite furnace atomic absorption spectrometric determination and solid phase extraction on Diaion HP-2MG
journal, February 2007
- Saygi, Kadriye O.; Melek, Esra; Tuzen, Mustafa
- Talanta, Vol. 71, Issue 3
Derivatives of lipoic acid, their preparation, their use as medicaments and the pharmaceutical compositions containing them
patent, May 2005
- Harnett, Jeremiah; Auguet, Michel; Chabrier de Lassauhyere, Pierre-Etienne
- US Patent Document 6,887,891
A no-carrier-added 72 Se/ 72 As radionuclide generator based on solid phase extraction
journal, September 2005
- Jennewein, M.; Qaim, Syed M.; Kulkarni, P. V.
- Radiochimica Acta, Vol. 93, Issue 9-10
Removal of selenium from water by complexation with polymeric dithiocarbamates
patent, April 1996
- Miller, Thomas M.; Goodman, Walter H.
- US Patent Document 5,510,040
1,2-Dithiolane derivatives
patent, October 2000
- Pershadsingh, Harrihar A.; Avery, Mitchell A.
- US Patent Document 6,127,394
Production of selenium-72 and arsenic-72
patent, April 1995
- Phillips, Dennis R.
- US Patent Document 5,405,589
Extracting information from the molten salt database
journal, December 2006
- Gadzuric, Slobodan; Suh, Changwon; Gaune-Escard, Marcelle
- Metallurgical and Materials Transactions A, Vol. 37, Issue 12
Radionuclide generator systems
journal, July 1974
- Lebowitz, E.; Richards, P.
- Seminars in Nuclear Medicine, Vol. 4, Issue 3
Studies on bulky residual group substituted arsenic(III) dithiocarbamate structures
journal, May 2003
- Wenclawiak, Bernd W.; Uttich, Stephan; Deiseroth, Hans Jörg
- Inorganica Chimica Acta, Vol. 348
Production of 73Se via (p, 3n) and (d, 4n) reactions on arsenic
journal, January 1988
- Mushtaq, A.; Qaim, S. M.; Stöcklin, G.
- International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, Vol. 39, Issue 10
Dithiocarbamate polymers
patent, November 1992
- Sparapany, John W.; Collins, John H.
- US Patent Document 5,164,095
Process for the production of radioisotopes of selenium
patent, November 1999
- Zhuikov, Boris L.; Kokhanyuk, Vladimir Mikhailovich
- US Patent Document 5,987,087
Production of selenium-72 and arsenic-72
patent, April 1993
- Phillips, Dennis R.
- US Patent Document 5,204,072
Production of selenium-72 and arsenic-72
patent, December 1994
- Phillips, Dennis R.
- US Patent Document 5,371,372