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Title: Method for non-contact particle manipulation and control of particle spacing along an axis

Abstract

One or more of the embodiments of the present invention provide for a method of non-contact particle manipulation and control of particle spacing along an axis which includes axial and radial acoustic standing wave fields. Particles are suspended in an aqueous solution, and this solution then flows into the cylindrical flow channel. While the solution flows through the flow channel, the outer structure of the flow channel is vibrated at a resonant frequency, causing a radial acoustic standing wave field to form inside the flow channel in the solution. These radial acoustic standing waves focus the particles suspended in the solution to the center axis of the cylindrical flow channel. At the same time, a transducer is used to create an axial acoustic standing wave field in the flow channel parallel to the axis of the flow channel. This drives the particles, which are already being focused to the center axis of the flow channel, to nodes or anti-nodes of the axial standing wave at half-wavelength intervals, depending on whether the particles are more or less dense and more or less compressible than the surrounding fluid.

Inventors:
; ; ;
Issue Date:
Research Org.:
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1092905
Patent Number(s):
8528406
Application Number:
11/923,403
Assignee:
Los Alamos National Security, LLP (Los Alamos, NM)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC52-06NA25396
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS

Citation Formats

Goddard, Gregory Russ, Kaduchak, Gregory, Jett, James Hubert, and Graves, Steven Wayde. Method for non-contact particle manipulation and control of particle spacing along an axis. United States: N. p., 2013. Web.
Goddard, Gregory Russ, Kaduchak, Gregory, Jett, James Hubert, & Graves, Steven Wayde. Method for non-contact particle manipulation and control of particle spacing along an axis. United States.
Goddard, Gregory Russ, Kaduchak, Gregory, Jett, James Hubert, and Graves, Steven Wayde. Tue . "Method for non-contact particle manipulation and control of particle spacing along an axis". United States. https://www.osti.gov/servlets/purl/1092905.
@article{osti_1092905,
title = {Method for non-contact particle manipulation and control of particle spacing along an axis},
author = {Goddard, Gregory Russ and Kaduchak, Gregory and Jett, James Hubert and Graves, Steven Wayde},
abstractNote = {One or more of the embodiments of the present invention provide for a method of non-contact particle manipulation and control of particle spacing along an axis which includes axial and radial acoustic standing wave fields. Particles are suspended in an aqueous solution, and this solution then flows into the cylindrical flow channel. While the solution flows through the flow channel, the outer structure of the flow channel is vibrated at a resonant frequency, causing a radial acoustic standing wave field to form inside the flow channel in the solution. These radial acoustic standing waves focus the particles suspended in the solution to the center axis of the cylindrical flow channel. At the same time, a transducer is used to create an axial acoustic standing wave field in the flow channel parallel to the axis of the flow channel. This drives the particles, which are already being focused to the center axis of the flow channel, to nodes or anti-nodes of the axial standing wave at half-wavelength intervals, depending on whether the particles are more or less dense and more or less compressible than the surrounding fluid.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Sep 10 00:00:00 EDT 2013},
month = {Tue Sep 10 00:00:00 EDT 2013}
}

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Flow cytometer
patent, January 2009


Force field particle filter, combining ultrasound standing waves and laminar flow
journal, May 2001


Particle analysis in an acoustic cytometer
patent-application, June 2009


Flow cell apparatus
patent, November 1997