Method and system for the diagnosis of disease using retinal image content and an archive of diagnosed human patient data

Tobin, Kenneth W; Karnowski, Thomas P; Chaum, Edward

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Title: Method and system for the diagnosis of disease using retinal image content and an archive of diagnosed human patient data

Abstract

A method for diagnosing diseases having retinal manifestations including retinal pathologies includes the steps of providing a CBIR system including an archive of stored digital retinal photography images and diagnosed patient data corresponding to the retinal photography images, the stored images each indexed in a CBIR database using a plurality of feature vectors, the feature vectors corresponding to distinct descriptive characteristics of the stored images. A query image of the retina of a patient is obtained. Using image processing, regions or structures in the query image are identified. The regions or structures are then described using the plurality of feature vectors. At least one relevant stored image from the archive based on similarity to the regions or structures is retrieved, and an eye disease or a disease having retinal manifestations in the patient is diagnosed based on the diagnosed patient data associated with the relevant stored image(s).

Inventors:: Tobin, Kenneth W; Karnowski, Thomas P; Chaum, Edward

Issue Date:: 2013-08-06

Research Org.:: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1089392

Patent Number(s):: 8503749

Application Number:: 13/471,720

Assignee:: UT-Battelle, LLC (Oak Ridge, TN); University of Tennessee Research Foundation (Knoxville, TN)

Patent Classifications (CPCs):: A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS

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A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
A61B3/12 - for looking at the eye fundus, e.g. ophthalmoscopes

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DOE Contract Number:: AC05-00OR22725

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: 59 BASIC BIOLOGICAL SCIENCES

Citation Formats


                    Tobin, Kenneth W, Karnowski, Thomas P, and Chaum, Edward. Method and system for the diagnosis of disease using retinal image content and an archive of diagnosed human patient data.  United States: N. p., 2013. 
        Web.

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                    Tobin, Kenneth W, Karnowski, Thomas P, & Chaum, Edward. Method and system for the diagnosis of disease using retinal image content and an archive of diagnosed human patient data.  United States.

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                    Tobin, Kenneth W, Karnowski, Thomas P, and Chaum, Edward. Tue .  
        "Method and system for the diagnosis of disease using retinal image content and an archive of diagnosed human patient data".  United States.  https://www.osti.gov/servlets/purl/1089392.

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@article{osti_1089392,

  title        = {Method and system for the diagnosis of disease using retinal image content and an archive of diagnosed human patient data},

  author       = {Tobin, Kenneth W and Karnowski, Thomas P and Chaum, Edward},

  abstractNote = {A method for diagnosing diseases having retinal manifestations including retinal pathologies includes the steps of providing a CBIR system including an archive of stored digital retinal photography images and diagnosed patient data corresponding to the retinal photography images, the stored images each indexed in a CBIR database using a plurality of feature vectors, the feature vectors corresponding to distinct descriptive characteristics of the stored images. A query image of the retina of a patient is obtained. Using image processing, regions or structures in the query image are identified. The regions or structures are then described using the plurality of feature vectors. At least one relevant stored image from the archive based on similarity to the regions or structures is retrieved, and an eye disease or a disease having retinal manifestations in the patient is diagnosed based on the diagnosed patient data associated with the relevant stored image(s).},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2013},

  month        = {8}

}

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Title: Method and system for the diagnosis of disease using retinal image content and an archive of diagnosed human patient data

Abstract

Citation Formats

Methods of imaging based on wavelet retrieval of scenes patent, June 2004

System and method for eye screening patent, February 2003

Method for determining binocular balance and disorders of binocularity of an individual or clinical groups of individuals patent, September 2006

Content-based retrieval of ophthalmological images conference, January 1996

Method for analyzing the optic disc from stereo color photographs using vascular landmarks patent, July 2002

Apparatus and method for assessing retinal damage patent, April 2009

Method for localizing and isolating an errant process step patent, March 2003

Apparatus and method of diagnosis of optically identifiable ophthalmic conditions patent, August 2009

Perceptual similarity image retrieval patent, April 2006

Image query system and method patent, November 1996

Image control apparatus, image control method and program patent, April 2009

Retinal disease analyzer patent, April 2000

Medical image management system and method patent, January 2004

Computerized medical diagnostic system patent, March 1999

Computer readable recording medium recorded with diagnosis supporting program, diagnosis supporting apparatus and diagnosis supporting method patent, August 2005

Method for representing and comparing digital images patent, February 2004

Ocular fundus portion analyzer and ocular fundus portion analyzing method patent, March 2009

Computer assisted methods for diagnosing diseases patent, October 2001

Medical image management system patent, August 2005

Early glaucoma detection by Fourier transform analysis of digitized eye fundus images patent, August 1993

Method for indexing and retrieving manufacturing-specific digital imagery based on image content patent, June 2004

Automated background processing mammographic image data patent, May 2005

Retinal disease analyzer patent, February 1999

Resemblance retrieval apparatus, and recording medium for recording resemblance retrieval program patent, September 2001

Automatic detection of red lesions in digital color fundus photographs patent, January 2009

System and method for performing image-based diagnosis patent, September 2000

Collaborative diagnostic systems patent, April 2006

Computer aided diagnostic assistance for medical imaging patent, July 2007

Ophthalmologic image processor patent, August 2000

Spectral bio-imaging of the eye patent, April 2003

Method for verifying users and updating database, and face verification system using the same patent, March 2007

Medical media file management system and method patent, December 2007

Visual image database search engine which allows for different schema patent, June 1999

Image retrieval system using a query image patent, September 2001

Evaluating disease progression using magnetic resonance imaging patent, May 2003

Method for the reduction of image content redundancy in large image databases patent, March 2010

System and method for performing probabilistic classification and decision support using multidimensional medical image databases patent, December 2008

Method for generating a unique and consistent signal pattern for identification of an individual patent, January 2006

System and method for measuring image similarity based on semantic meaning patent, May 2006

Methods, devices and systems for assessing eye disease patent, May 2007

Similar image search system patent, May 2008

Automated diagnosis and image understanding with object extraction, object classification, and inferencing in retinal images conference, January 1996

Method and system for detecting a geometrically transformed copy of an image patent, June 2007

Analysis of fundus images patent, February 2006

Ophthalmological image processor patent, December 1993

Object based image retrieval patent, January 2009

Methods of imaging based on wavelet retrieval of scenes
patent, June 2004

System and method for eye screening
patent, February 2003

Method for determining binocular balance and disorders of binocularity of an individual or clinical groups of individuals
patent, September 2006

Content-based retrieval of ophthalmological images
conference, January 1996

Method for analyzing the optic disc from stereo color photographs using vascular landmarks
patent, July 2002

Apparatus and method for assessing retinal damage
patent, April 2009

Method for localizing and isolating an errant process step
patent, March 2003

Apparatus and method of diagnosis of optically identifiable ophthalmic conditions
patent, August 2009

Perceptual similarity image retrieval
patent, April 2006

Image query system and method
patent, November 1996

Image control apparatus, image control method and program
patent, April 2009

Retinal disease analyzer
patent, April 2000

Medical image management system and method
patent, January 2004

Computerized medical diagnostic system
patent, March 1999

Computer readable recording medium recorded with diagnosis supporting program, diagnosis supporting apparatus and diagnosis supporting method
patent, August 2005

Method for representing and comparing digital images
patent, February 2004

Ocular fundus portion analyzer and ocular fundus portion analyzing method
patent, March 2009

Computer assisted methods for diagnosing diseases
patent, October 2001

Medical image management system
patent, August 2005

Early glaucoma detection by Fourier transform analysis of digitized eye fundus images
patent, August 1993

Method for indexing and retrieving manufacturing-specific digital imagery based on image content
patent, June 2004

Automated background processing mammographic image data
patent, May 2005

Retinal disease analyzer
patent, February 1999

Resemblance retrieval apparatus, and recording medium for recording resemblance retrieval program
patent, September 2001

Automatic detection of red lesions in digital color fundus photographs
patent, January 2009

System and method for performing image-based diagnosis
patent, September 2000

Collaborative diagnostic systems
patent, April 2006

Computer aided diagnostic assistance for medical imaging
patent, July 2007

Ophthalmologic image processor
patent, August 2000

Spectral bio-imaging of the eye
patent, April 2003

Method for verifying users and updating database, and face verification system using the same
patent, March 2007

Medical media file management system and method
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Visual image database search engine which allows for different schema
patent, June 1999

Image retrieval system using a query image
patent, September 2001

Evaluating disease progression using magnetic resonance imaging
patent, May 2003

Method for the reduction of image content redundancy in large image databases
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System and method for performing probabilistic classification and decision support using multidimensional medical image databases
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Method for generating a unique and consistent signal pattern for identification of an individual
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Similar image search system
patent, May 2008

Automated diagnosis and image understanding with object extraction, object classification, and inferencing in retinal images
conference, January 1996

Method and system for detecting a geometrically transformed copy of an image
patent, June 2007

Analysis of fundus images
patent, February 2006

Ophthalmological image processor
patent, December 1993

Object based image retrieval
patent, January 2009