Electrospray ion source with reduced analyte electrochemistry
Abstract
An electrospray ion (ESI) source and method capable of ionizing an analyte molecule without oxidizing or reducing the analyte of interest. The ESI source can include an emitter having a liquid conduit, a working electrode having a liquid contacting surface, a spray tip, a secondary working electrode, and a charge storage coating covering partially or fully the liquid contacting surface of the working electrode. The liquid conduit, the working electrode and the secondary working electrode can be in liquid communication. The electrospray ion source can also include a counter electrode proximate to, but separated from, said spray tip. The electrospray ion source can also include a power system for applying a voltage difference between the working electrodes and a counter-electrode. The power system can deliver pulsed voltage changes to the working electrodes during operation of said electrospray ion source to minimize the surface potential of the charge storage coating.
- Inventors:
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1088944
- Patent Number(s):
- 8497473
- Application Number:
- 13/207,783
- Assignee:
- UT-Battelle, LLC (Oak Ridge, TN)
- Patent Classifications (CPCs):
-
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Kertesz, Vilmos, and Van Berkel, Gary J. Electrospray ion source with reduced analyte electrochemistry. United States: N. p., 2013.
Web.
Kertesz, Vilmos, & Van Berkel, Gary J. Electrospray ion source with reduced analyte electrochemistry. United States.
Kertesz, Vilmos, and Van Berkel, Gary J. Tue .
"Electrospray ion source with reduced analyte electrochemistry". United States. https://www.osti.gov/servlets/purl/1088944.
@article{osti_1088944,
title = {Electrospray ion source with reduced analyte electrochemistry},
author = {Kertesz, Vilmos and Van Berkel, Gary J},
abstractNote = {An electrospray ion (ESI) source and method capable of ionizing an analyte molecule without oxidizing or reducing the analyte of interest. The ESI source can include an emitter having a liquid conduit, a working electrode having a liquid contacting surface, a spray tip, a secondary working electrode, and a charge storage coating covering partially or fully the liquid contacting surface of the working electrode. The liquid conduit, the working electrode and the secondary working electrode can be in liquid communication. The electrospray ion source can also include a counter electrode proximate to, but separated from, said spray tip. The electrospray ion source can also include a power system for applying a voltage difference between the working electrodes and a counter-electrode. The power system can deliver pulsed voltage changes to the working electrodes during operation of said electrospray ion source to minimize the surface potential of the charge storage coating.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jul 30 00:00:00 EDT 2013},
month = {Tue Jul 30 00:00:00 EDT 2013}
}
Works referenced in this record:
Combined electrophoresis-electrospray interface and method
patent, October 1994
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- US Patent Document RE34,757
Charged droplet sprayers
patent, November 2009
- Whitehouse, Craig M.; White, Thomas
- US Patent Document 7,619,216
Microscale Electrochemical Cell And Methods Incorporating The Cell
patent-application, July 2008
- Arnold, Don W.; Jiang, Guifeng; Hebert, Nicole E.
- US Patent Application 11/627877; 20080182136
Electrospray ion source with reduced analyte electrochemistry
patent, August 2011
- Kertesz, Vilmos; Van Berkel, Gary J.
- US Patent Document 8,003,937