Structure-sequence based analysis for identification of conserved regions in proteins
Abstract
Disclosed are computational methods, and associated hardware and software products for scoring conservation in a protein structure based on a computationally identified family or cluster of protein structures. A method of computationally identifying a family or cluster of protein structures in also disclosed herein.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1083788
- Patent Number(s):
- 8452542
- Application Number:
- 11/890,864
- Assignee:
- Lawrence Livermore National Security, LLC. (Livermore, CA)
- Patent Classifications (CPCs):
-
G - PHYSICS G16 - INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS G16B - BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Zemla, Adam T, Zhou, Carol E, Lam, Marisa W, Smith, Jason R, and Pardes, Elizabeth. Structure-sequence based analysis for identification of conserved regions in proteins. United States: N. p., 2013.
Web.
Zemla, Adam T, Zhou, Carol E, Lam, Marisa W, Smith, Jason R, & Pardes, Elizabeth. Structure-sequence based analysis for identification of conserved regions in proteins. United States.
Zemla, Adam T, Zhou, Carol E, Lam, Marisa W, Smith, Jason R, and Pardes, Elizabeth. Tue .
"Structure-sequence based analysis for identification of conserved regions in proteins". United States. https://www.osti.gov/servlets/purl/1083788.
@article{osti_1083788,
title = {Structure-sequence based analysis for identification of conserved regions in proteins},
author = {Zemla, Adam T and Zhou, Carol E and Lam, Marisa W and Smith, Jason R and Pardes, Elizabeth},
abstractNote = {Disclosed are computational methods, and associated hardware and software products for scoring conservation in a protein structure based on a computationally identified family or cluster of protein structures. A method of computationally identifying a family or cluster of protein structures in also disclosed herein.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue May 28 00:00:00 EDT 2013},
month = {Tue May 28 00:00:00 EDT 2013}
}
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