High temperature flow-through device for rapid solubilization and analysis
Abstract
Devices and methods for thermally lysing of biological material, for example vegetative bacterial cells and bacterial spores, are provided. Hot solution methods for solubilizing bacterial spores are described. Systems for direct analysis are disclosed including thermal lysers coupled to sample preparation stations. Integrated systems capable of performing sample lysis, labeling and protein fingerprint analysis of biological material, for example, vegetative bacterial cells, bacterial spores and viruses are provided.
- Inventors:
- Issue Date:
- Research Org.:
- SNL-L (Sandia National Laboratories, Livermore, CA (United States))
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1083601
- Patent Number(s):
- 8426135
- Application Number:
- 13/308,228
- Assignee:
- Sandia National Laboratories (Livermore, CA)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
C - CHEMISTRY C12 - BIOCHEMISTRY C12M - APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
West, Jason A. A., Hukari, Kyle W., Patel, Kamlesh D., Peterson, Kenneth A., and Renzi, Ronald F. High temperature flow-through device for rapid solubilization and analysis. United States: N. p., 2013.
Web.
West, Jason A. A., Hukari, Kyle W., Patel, Kamlesh D., Peterson, Kenneth A., & Renzi, Ronald F. High temperature flow-through device for rapid solubilization and analysis. United States.
West, Jason A. A., Hukari, Kyle W., Patel, Kamlesh D., Peterson, Kenneth A., and Renzi, Ronald F. Tue .
"High temperature flow-through device for rapid solubilization and analysis". United States. https://www.osti.gov/servlets/purl/1083601.
@article{osti_1083601,
title = {High temperature flow-through device for rapid solubilization and analysis},
author = {West, Jason A. A. and Hukari, Kyle W. and Patel, Kamlesh D. and Peterson, Kenneth A. and Renzi, Ronald F.},
abstractNote = {Devices and methods for thermally lysing of biological material, for example vegetative bacterial cells and bacterial spores, are provided. Hot solution methods for solubilizing bacterial spores are described. Systems for direct analysis are disclosed including thermal lysers coupled to sample preparation stations. Integrated systems capable of performing sample lysis, labeling and protein fingerprint analysis of biological material, for example, vegetative bacterial cells, bacterial spores and viruses are provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 23 00:00:00 EDT 2013},
month = {Tue Apr 23 00:00:00 EDT 2013}
}
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