Materials and methods for efficient lactic acid production
Abstract
The present invention provides derivatives of Escherichia coli constructed for the production of lactic acid. The transformed E. coli of the invention are prepared by deleting the genes that encode competing pathways followed by a growth-based selection for mutants with improved performance. These transformed E. coli are useful for providing an increased supply of lactic acid for use in food and industrial applications.
- Inventors:
- Issue Date:
- Research Org.:
- University of Florida Research Foundation, Inc. (Gainesville, FL)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1083310
- Patent Number(s):
- 8426191
- Application Number:
- 12/632,041
- Assignee:
- University of Florida Research Foundation, Inc. (Gainesville, FL)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
- DOE Contract Number:
- FG02-96ER20222; FG36-04GO14019
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Zhou, Shengde, Ingram, Lonnie O'Neal, Shanmugam, Keelnatham T, Yomano, Lorraine, Grabar, Tammy B, and Moore, Jonathan C. Materials and methods for efficient lactic acid production. United States: N. p., 2013.
Web.
Zhou, Shengde, Ingram, Lonnie O'Neal, Shanmugam, Keelnatham T, Yomano, Lorraine, Grabar, Tammy B, & Moore, Jonathan C. Materials and methods for efficient lactic acid production. United States.
Zhou, Shengde, Ingram, Lonnie O'Neal, Shanmugam, Keelnatham T, Yomano, Lorraine, Grabar, Tammy B, and Moore, Jonathan C. Tue .
"Materials and methods for efficient lactic acid production". United States. https://www.osti.gov/servlets/purl/1083310.
@article{osti_1083310,
title = {Materials and methods for efficient lactic acid production},
author = {Zhou, Shengde and Ingram, Lonnie O'Neal and Shanmugam, Keelnatham T and Yomano, Lorraine and Grabar, Tammy B and Moore, Jonathan C},
abstractNote = {The present invention provides derivatives of Escherichia coli constructed for the production of lactic acid. The transformed E. coli of the invention are prepared by deleting the genes that encode competing pathways followed by a growth-based selection for mutants with improved performance. These transformed E. coli are useful for providing an increased supply of lactic acid for use in food and industrial applications.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 23 00:00:00 EDT 2013},
month = {Tue Apr 23 00:00:00 EDT 2013}
}
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Materials and methods for efficient lactic acid production
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Works referencing / citing this record:
Materials and methods for efficient lactic acid production
patent, April 2013
- Zhou, Shengde; Ingram, Lonnie O'Neal; Shanmugam, Keelnatham T.
- US Patent Document 8,426,191
Materials and methods for efficient lactic acid production
patent, April 2013
- Zhou, Shengde; Ingram, Lonnie O'Neal; Shanmugam, Keelnatham T.
- US Patent Document 8,426,191