skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Recombinant microorganisms for increased production of organic acids

Abstract

Disclosed are recombinant microorganisms for producing organic acids. The recombinant microorganisms express a polypeptide that has the enzymatic activity of an enzyme that is utilized in the pentose phosphate cycle. The recombinant microorganism may include recombinant Actinobacillus succinogenes that has been transformed to express a Zwischenferment (Zwf) gene. The recombinant microorganisms may be useful in fermentation processes for producing organic acids such as succinic acid and lactic acid. Also disclosed are novel plasmids that are useful for transforming microorganisms to produce recombinant microorganisms that express enzymes such as Zwf.

Inventors:
; ;
Issue Date:
Research Org.:
Michigan Biotechnology Institute (Lansing, MI)
Sponsoring Org.:
USDOE
OSTI Identifier:
1083279
Patent Number(s):
8431373
Application Number:
13/328,894
Assignee:
Michigan Biotechnology Institute (Lansing, MI)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
FC36-02GO12001
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Yi, Jian, Kleff, Susanne, and Guettler, Michael V. Recombinant microorganisms for increased production of organic acids. United States: N. p., 2013. Web.
Yi, Jian, Kleff, Susanne, & Guettler, Michael V. Recombinant microorganisms for increased production of organic acids. United States.
Yi, Jian, Kleff, Susanne, and Guettler, Michael V. Tue . "Recombinant microorganisms for increased production of organic acids". United States. https://www.osti.gov/servlets/purl/1083279.
@article{osti_1083279,
title = {Recombinant microorganisms for increased production of organic acids},
author = {Yi, Jian and Kleff, Susanne and Guettler, Michael V},
abstractNote = {Disclosed are recombinant microorganisms for producing organic acids. The recombinant microorganisms express a polypeptide that has the enzymatic activity of an enzyme that is utilized in the pentose phosphate cycle. The recombinant microorganism may include recombinant Actinobacillus succinogenes that has been transformed to express a Zwischenferment (Zwf) gene. The recombinant microorganisms may be useful in fermentation processes for producing organic acids such as succinic acid and lactic acid. Also disclosed are novel plasmids that are useful for transforming microorganisms to produce recombinant microorganisms that express enzymes such as Zwf.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2013},
month = {4}
}

Patent:

Save / Share: