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Title: In vivo imaging of sulfotransferases

Abstract

Radiolabeled tracers for sulfotransferases (SULTs), their synthesis, and their use are provided. Included are substituted phenols, naphthols, coumarins, and flavones radiolabeled with .sup.18F, .sup.123I, .sup.124I, .sup.125I, or .sup.11C. Also provided are in vivo techniques for using these and other tracers as analytical and diagnostic tools to study sulfotransferase distribution and activity, in health and disease, and to evaluate therapeutic interventions.

Inventors:
; ; ;
Issue Date:
Research Org.:
The Regents of the University of California (Oakland, CA)
Sponsoring Org.:
USDOE
OSTI Identifier:
1083200
Patent Number(s):
8,372,380
Application Number:
12/594,197
Assignee:
The Regents of the University of California (Oakland, CA)
DOE Contract Number:  
FC02-02ER63420
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Barrio, Jorge R, Kepe, Vladimir, Small, Gary W, and Satyamurthy, Nagichettiar. In vivo imaging of sulfotransferases. United States: N. p., 2013. Web.
Barrio, Jorge R, Kepe, Vladimir, Small, Gary W, & Satyamurthy, Nagichettiar. In vivo imaging of sulfotransferases. United States.
Barrio, Jorge R, Kepe, Vladimir, Small, Gary W, and Satyamurthy, Nagichettiar. Tue . "In vivo imaging of sulfotransferases". United States. https://www.osti.gov/servlets/purl/1083200.
@article{osti_1083200,
title = {In vivo imaging of sulfotransferases},
author = {Barrio, Jorge R and Kepe, Vladimir and Small, Gary W and Satyamurthy, Nagichettiar},
abstractNote = {Radiolabeled tracers for sulfotransferases (SULTs), their synthesis, and their use are provided. Included are substituted phenols, naphthols, coumarins, and flavones radiolabeled with .sup.18F, .sup.123I, .sup.124I, .sup.125I, or .sup.11C. Also provided are in vivo techniques for using these and other tracers as analytical and diagnostic tools to study sulfotransferase distribution and activity, in health and disease, and to evaluate therapeutic interventions.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2013},
month = {2}
}

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Works referenced in this record:

The ATP-waiting conformation of rotating F1-ATPase revealed by single-pair fluorescence resonance energy transfer
journal, July 2003

  • Yasuda, R.; Masaike, T.; Adachi, K.
  • Proceedings of the National Academy of Sciences, Vol. 100, Issue 16
  • DOI: 10.1073/pnas.1637860100