System for particle concentration and detection
Abstract
A new microfluidic system comprising an automated prototype insulator-based dielectrophoresis (iDEP) triggering microfluidic device for pathogen monitoring that can eventually be run outside the laboratory in a real world environment has been used to demonstrate the feasibility of automated trapping and detection of particles. The system broadly comprised an aerosol collector for collecting air-borne particles, an iDEP chip within which to temporarily trap the collected particles and a laser and fluorescence detector with which to induce a fluorescence signal and detect a change in that signal as particles are trapped within the iDEP chip.
- Inventors:
- Issue Date:
- Research Org.:
- Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1083037
- Patent Number(s):
- 8398839
- Application Number:
- 12/793,370
- Assignee:
- Sandia Corporation (Albuquerque, NM)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B03 - SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS B03C - MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Morales, Alfredo M., Whaley, Josh A., Zimmerman, Mark D., Renzi, Ronald F., Tran, Huu M., Maurer, Scott M., and Munslow, William D. System for particle concentration and detection. United States: N. p., 2013.
Web.
Morales, Alfredo M., Whaley, Josh A., Zimmerman, Mark D., Renzi, Ronald F., Tran, Huu M., Maurer, Scott M., & Munslow, William D. System for particle concentration and detection. United States.
Morales, Alfredo M., Whaley, Josh A., Zimmerman, Mark D., Renzi, Ronald F., Tran, Huu M., Maurer, Scott M., and Munslow, William D. Tue .
"System for particle concentration and detection". United States. https://www.osti.gov/servlets/purl/1083037.
@article{osti_1083037,
title = {System for particle concentration and detection},
author = {Morales, Alfredo M. and Whaley, Josh A. and Zimmerman, Mark D. and Renzi, Ronald F. and Tran, Huu M. and Maurer, Scott M. and Munslow, William D.},
abstractNote = {A new microfluidic system comprising an automated prototype insulator-based dielectrophoresis (iDEP) triggering microfluidic device for pathogen monitoring that can eventually be run outside the laboratory in a real world environment has been used to demonstrate the feasibility of automated trapping and detection of particles. The system broadly comprised an aerosol collector for collecting air-borne particles, an iDEP chip within which to temporarily trap the collected particles and a laser and fluorescence detector with which to induce a fluorescence signal and detect a change in that signal as particles are trapped within the iDEP chip.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 19 00:00:00 EDT 2013},
month = {Tue Mar 19 00:00:00 EDT 2013}
}
Works referenced in this record:
Sample concentration and impedance detection on a microfluidic polymer chip
journal, May 2008
- Sabounchi, Poorya; Morales, Alfredo M.; Ponce, Pierre
- Biomedical Microdevices, Vol. 10, Issue 5
Performance impact of dynamic surface coatings on polymeric insulator-based dielectrophoretic particle separators
journal, July 2007
- Davalos, Rafael V.; McGraw, Gregory J.; Wallow, Thomas I.
- Analytical and Bioanalytical Chemistry, Vol. 390, Issue 3
Modular optical detector system
patent, February 2006
- Horn, Brent A.; Renzi, Ronald F.
- US Patent Document 6,998,598
Dielectrophoresis Device and Method Having Non-uniform Arrays for Manipulating Particles
patent-application, October 2004
- Cummings, Eric B.; Fintschenko, Yolanda; Simmons, Blake
- US Patent Application 10/760139; 20040211669
Insulator-Based DEP With Impedance Measurements for Analyte Detection
patent-application, May 2008
- Davalos, Rafael V.; Simmons, Blake A.; Crocker, Robert W. Robert W.
- US Patent Application 11/556685; 20080105565