Methods for neutralizing anthrax or anthrax spores
Abstract
The present invention concerns methods, compositions and apparatus for neutralizing bioagents, wherein bioagents comprise biowarfare agents, biohazardous agents, biological agents and/or infectious agents. The methods comprise exposing the bioagent to an organic semiconductor and exposing the bioagent and organic semiconductor to a source of energy. Although any source of energy is contemplated, in some embodiments the energy comprises visible light, ultraviolet, infrared, radiofrequency, microwave, laser radiation, pulsed corona discharge or electron beam radiation. Exemplary organic semiconductors include DAT and DALM. In certain embodiments, the organic semiconductor may be attached to one or more binding moieties, such as an antibody, antibody fragment, or nucleic acid ligand. Preferably, the binding moiety has a binding affinity for one or more bioagents to be neutralized. Other embodiments concern an apparatus comprising an organic semiconductor and an energy source. In preferred embodiments, the methods, compositions and apparatus are used for neutralizing anthrax spores.
- Inventors:
- Issue Date:
- Research Org.:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1082844
- Patent Number(s):
- 8383036
- Application Number:
- 12/973,681
- Assignee:
- Conceptual Mindworks, Inc. (San Antonio, TX)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
- DOE Contract Number:
- AC06-76RL01830
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES
Citation Formats
Sloan, Mark A, Vivekandanda, Jeevalatha, Holwitt, Eric A, and Kiel, Johnathan L. Methods for neutralizing anthrax or anthrax spores. United States: N. p., 2013.
Web.
Sloan, Mark A, Vivekandanda, Jeevalatha, Holwitt, Eric A, & Kiel, Johnathan L. Methods for neutralizing anthrax or anthrax spores. United States.
Sloan, Mark A, Vivekandanda, Jeevalatha, Holwitt, Eric A, and Kiel, Johnathan L. Tue .
"Methods for neutralizing anthrax or anthrax spores". United States. https://www.osti.gov/servlets/purl/1082844.
@article{osti_1082844,
title = {Methods for neutralizing anthrax or anthrax spores},
author = {Sloan, Mark A and Vivekandanda, Jeevalatha and Holwitt, Eric A and Kiel, Johnathan L},
abstractNote = {The present invention concerns methods, compositions and apparatus for neutralizing bioagents, wherein bioagents comprise biowarfare agents, biohazardous agents, biological agents and/or infectious agents. The methods comprise exposing the bioagent to an organic semiconductor and exposing the bioagent and organic semiconductor to a source of energy. Although any source of energy is contemplated, in some embodiments the energy comprises visible light, ultraviolet, infrared, radiofrequency, microwave, laser radiation, pulsed corona discharge or electron beam radiation. Exemplary organic semiconductors include DAT and DALM. In certain embodiments, the organic semiconductor may be attached to one or more binding moieties, such as an antibody, antibody fragment, or nucleic acid ligand. Preferably, the binding moiety has a binding affinity for one or more bioagents to be neutralized. Other embodiments concern an apparatus comprising an organic semiconductor and an energy source. In preferred embodiments, the methods, compositions and apparatus are used for neutralizing anthrax spores.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2013},
month = {2}
}
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