skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: In vivo spectral micro-imaging of tissue

Abstract

In vivo endoscopic methods an apparatuses for implementation of fluorescence and autofluorescence microscopy, with and without the use of exogenous agents, effectively (with resolution sufficient to image nuclei) visualize and categorize various abnormal tissue forms.

Inventors:
; ; ; ;
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1080282
Patent Number(s):
8320650
Application Number:
12/615,085
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA); The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
G - PHYSICS G02 - OPTICS G02B - OPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
DOE Contract Number:  
AC52-07NA27344
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Demos, Stavros G, Urayama, Shiro, Lin, Bevin, Saroufeem, Ramez, and Ghobrial, Moussa. In vivo spectral micro-imaging of tissue. United States: N. p., 2012. Web.
Demos, Stavros G, Urayama, Shiro, Lin, Bevin, Saroufeem, Ramez, & Ghobrial, Moussa. In vivo spectral micro-imaging of tissue. United States.
Demos, Stavros G, Urayama, Shiro, Lin, Bevin, Saroufeem, Ramez, and Ghobrial, Moussa. Tue . "In vivo spectral micro-imaging of tissue". United States. https://www.osti.gov/servlets/purl/1080282.
@article{osti_1080282,
title = {In vivo spectral micro-imaging of tissue},
author = {Demos, Stavros G and Urayama, Shiro and Lin, Bevin and Saroufeem, Ramez and Ghobrial, Moussa},
abstractNote = {In vivo endoscopic methods an apparatuses for implementation of fluorescence and autofluorescence microscopy, with and without the use of exogenous agents, effectively (with resolution sufficient to image nuclei) visualize and categorize various abnormal tissue forms.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2012},
month = {11}
}

Patent:

Save / Share:

Works referenced in this record:

Detection of preinvasive cancer cells
journal, July 2000


Laser-induced fluorescence spectroscopy of human colonic mucosa
journal, July 1990


Two-photon laser scanning fluorescence microscopy
journal, April 1990


Confocal Examination of Nonmelanoma Cancers in Thick Skin Excisions to Potentially Guide Mohs Micrographic Surgery Without Frozen Histopathology
journal, November 2001


Laser-induced autofluorescence microscopy of normal and tumor human colonic tissue
journal, January 2004


Second-harmonic imaging in the scanning optical microscope
journal, September 1978


Three-Dimensional Vibrational Imaging by Coherent Anti-Stokes Raman Scattering
journal, May 1999


Hyperspectral imaging of cells: toward real-time pathological assessment
conference, December 2003


Laser induced fluorescence spectroscopy from native cancerous and normal tissue
journal, December 1984


Spectroscopic Diagnosis Of Colonic Dysplasia
journal, June 1991


Characterization of human breast biopsy specimens with near-IR Raman spectroscopy
journal, February 1994


Cervical Precancer Detection Using a Multivariate Statistical Algorithm Based on Laser-Induced Fluorescence Spectra at Multiple Excitation Wavelengths
journal, October 1996