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Title: Compositions and methods for improved protein production

Abstract

The present invention relates to the identification of novel nucleic acid sequences, designated herein as 7p, 8k, 7E, 9G, 8Q and 203, in a host cell which effect protein production. The present invention also provides host cells having a mutation or deletion of part or all of the gene encoding 7p, 8k, 7E, 9G, 8Q and 203, which are presented in FIG. 1, and are SEQ ID NOS.: 1-6, respectively. The present invention also provides host cells further comprising a nucleic acid encoding a desired heterologous protein such as an enzyme.

Inventors:
 [1];  [2]
  1. San Carlos, CA
  2. San Francisco, CA
Issue Date:
Research Org.:
National Renewable Energy Lab. (NREL), Golden, CO (United States); Albany Research Center (ARC), Albany, OR (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1069103
Patent Number(s):
8216844
Application Number:
12/376,558
Assignee:
Danisco US Inc. (Palo Alto, CA)
Patent Classifications (CPCs):
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE Y02P - CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
AC36-99GO10337
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Bodie, Elizabeth A, and Kim, Steve. Compositions and methods for improved protein production. United States: N. p., 2012. Web.
Bodie, Elizabeth A, & Kim, Steve. Compositions and methods for improved protein production. United States.
Bodie, Elizabeth A, and Kim, Steve. Tue . "Compositions and methods for improved protein production". United States. https://www.osti.gov/servlets/purl/1069103.
@article{osti_1069103,
title = {Compositions and methods for improved protein production},
author = {Bodie, Elizabeth A and Kim, Steve},
abstractNote = {The present invention relates to the identification of novel nucleic acid sequences, designated herein as 7p, 8k, 7E, 9G, 8Q and 203, in a host cell which effect protein production. The present invention also provides host cells having a mutation or deletion of part or all of the gene encoding 7p, 8k, 7E, 9G, 8Q and 203, which are presented in FIG. 1, and are SEQ ID NOS.: 1-6, respectively. The present invention also provides host cells further comprising a nucleic acid encoding a desired heterologous protein such as an enzyme.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2012},
month = {7}
}

Patent:

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