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Title: Methods for chromosome-specific staining

Methods and compositions for chromosome-specific staining are provided. Compositions comprise heterogeneous mixtures of labeled nucleic acid fragments having substantially complementary base sequences to unique sequence regions of the chromosomal DNA for which their associated staining reagent is specific. Methods include ways for making the chromosome-specific staining compositions of the invention, and methods for applying the staining compositions to chromosomes. 3 figs.
Inventors:
;
Issue Date:
OSTI Identifier:
106686
Assignee:
Univ. Of California, Oakland, CA (United States) PTO; SCA: 550200; PA: EDB-95:138125; SN: 95001460056
Patent Number(s):
US 5,447,841/A/
Application Number:
PAN: 7-627,707
Contract Number:
W-7405-ENG-48
Resource Relation:
Other Information: PBD: 5 Sep 1995
Research Org:
University of California
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; STAINS; SPECIFICITY; CHEMICAL COMPOSITION; CHROMOSOMES; DNA SEQUENCING; CYTOLOGICAL TECHNIQUES

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